Determination of Binding Thermodynamics
dc.contributor.author | Dedon, Peter C. | |
dc.date.accessioned | 2018-05-15T20:16:05Z | |
dc.date.available | 2018-05-15T20:16:05Z | |
dc.date.issued | 2000-02 | |
dc.identifier.citation | Dedon, Peter C. (2000). "Determination of Binding Thermodynamics." Current Protocols in Nucleic Acid Chemistry 00(1): 8.2.1-8.2.8. | |
dc.identifier.issn | 1934-9270 | |
dc.identifier.issn | 1934-9289 | |
dc.identifier.uri | https://hdl.handle.net/2027.42/143787 | |
dc.description.abstract | This unit serves as a starting point for exploring the thermodynamic properties of interactions between small molecules and DNA. It covers the determination of simple, apparent association/dissociation constants. The concentration of DNA‐bound ligand and free ligand are determined and a binding constant is extracted from these data. Data gathering and curve fitting are discussed. | |
dc.publisher | Wiley Periodicals, Inc. | |
dc.publisher | JAI Press | |
dc.title | Determination of Binding Thermodynamics | |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | |
dc.subject.hlbsecondlevel | Chemical Engineering | |
dc.subject.hlbsecondlevel | Public Health | |
dc.subject.hlbsecondlevel | Biological Chemistry | |
dc.subject.hlbsecondlevel | Chemistry | |
dc.subject.hlbtoplevel | Health Sciences | |
dc.subject.hlbtoplevel | Science | |
dc.subject.hlbtoplevel | Engineering | |
dc.description.peerreviewed | Peer Reviewed | |
dc.description.bitstreamurl | https://deepblue.lib.umich.edu/bitstream/2027.42/143787/1/cpnc0802.pdf | |
dc.identifier.doi | 10.1002/0471142700.nc0802s00 | |
dc.identifier.source | Current Protocols in Nucleic Acid Chemistry | |
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dc.identifier.citedreference | Yu, L., Golik, J., Harrison, R., and Dedon, P. 1994. The deoxyfucose‐anthranilate of esperamicin A1 confers intercalative DNA binding and causes a switch in the chemistry of bistranded DNA lesions. J. Am. Chem. Soc. 116: 9733 ‐ 9738. | |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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