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The role of age in treatmentâ related adverse events in patients with head and neck cancer: A systematic review
dc.contributor.authorCoca‐pelaz, Andrés
dc.contributor.authorHalmos, Gyorgy B.
dc.contributor.authorStrojan, Primož
dc.contributor.authorBree, Remco
dc.contributor.authorBossi, Paolo
dc.contributor.authorBradford, Carol R.
dc.contributor.authorRinaldo, Alessandra
dc.contributor.authorVander Poorten, Vincent
dc.contributor.authorSanabria, Alvaro
dc.contributor.authorTakes, Robert P.
dc.contributor.authorFerlito, Alfio
dc.date.accessioned2019-06-20T17:04:17Z
dc.date.availableWITHHELD_14_MONTHS
dc.date.available2019-06-20T17:04:17Z
dc.date.issued2019-07
dc.identifier.citationCoca‐pelaz, Andrés ; Halmos, Gyorgy B.; Strojan, Primož ; Bree, Remco; Bossi, Paolo; Bradford, Carol R.; Rinaldo, Alessandra; Vander Poorten, Vincent; Sanabria, Alvaro; Takes, Robert P.; Ferlito, Alfio (2019). "The role of age in treatmentâ related adverse events in patients with head and neck cancer: A systematic review." Head & Neck 41(7): 2410-2429.
dc.identifier.issn1043-3074
dc.identifier.issn1097-0347
dc.identifier.urihttps://hdl.handle.net/2027.42/149496
dc.description.abstractHead and neck squamous cell carcinoma (HNSCC) is often diagnosed in advanced stage and therefore requires aggressive, multimodal treatment. Elderly patients are often excluded from standard therapy regimens purely based on age. This clinical review aims to collect all published data in the literature on treatment modality selection in elderly patients and on ageâ related adverse events following treatment of HNSCC. We performed a literature search for articles on the treatment of HNSCC in elderly patients. Most of the articles were retrospective studies with the consequent limitations. It can be concluded that age is not an absolute contraindication for intensive treatment and comorbidity is an important predictor of outcome, but not the only one. Despite the existence of multiple tools for pretreatment evaluation, there are not consistent data on their use.
dc.publisherJohn Wiley & Sons, Inc.
dc.subject.otherpostoperative complications
dc.subject.othertoxicity
dc.subject.otherhead and neck cancer
dc.subject.otherelderly
dc.subject.othercomorbidity
dc.subject.otheradverse events
dc.subject.otherprognosis
dc.titleThe role of age in treatmentâ related adverse events in patients with head and neck cancer: A systematic review
dc.typeArticle
dc.rights.robotsIndexNoFollow
dc.subject.hlbsecondlevelOtolaryngology
dc.subject.hlbtoplevelHealth Sciences
dc.description.peerreviewedPeer Reviewed
dc.description.bitstreamurlhttps://deepblue.lib.umich.edu/bitstream/2027.42/149496/1/hed25696_am.pdf
dc.description.bitstreamurlhttps://deepblue.lib.umich.edu/bitstream/2027.42/149496/2/hed25696.pdf
dc.identifier.doi10.1002/hed.25696
dc.identifier.sourceHead & Neck
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dc.owningcollnameInterdisciplinary and Peer-Reviewed


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