A phase 1 and randomized controlled phase 2 trial of the safety and efficacy of the combination of gemcitabine and docetaxel with ontuxizumab (MORAb‐004) in metastatic soft‐tissue sarcomas
dc.contributor.author | Jones, Robin L. | |
dc.contributor.author | Chawla, Sant P. | |
dc.contributor.author | Attia, Steven | |
dc.contributor.author | Schöffski, Patrick | |
dc.contributor.author | Gelderblom, Hans | |
dc.contributor.author | Chmielowski, Bartosz | |
dc.contributor.author | Le Cesne, Axel | |
dc.contributor.author | Van Tine, Brian A. | |
dc.contributor.author | Trent, Jonathan C. | |
dc.contributor.author | Patel, Shreyaskumar | |
dc.contributor.author | Wagner, Andrew J. | |
dc.contributor.author | Chugh, Rashmi | |
dc.contributor.author | Heyburn, John W. | |
dc.contributor.author | Weil, Susan C. | |
dc.contributor.author | Wang, Wenquan | |
dc.contributor.author | Viele, Kert | |
dc.contributor.author | Maki, Robert G. | |
dc.date.accessioned | 2019-07-03T19:56:18Z | |
dc.date.available | WITHHELD_13_MONTHS | |
dc.date.available | 2019-07-03T19:56:18Z | |
dc.date.issued | 2019-07-15 | |
dc.identifier.citation | Jones, Robin L.; Chawla, Sant P.; Attia, Steven; Schöffski, Patrick ; Gelderblom, Hans; Chmielowski, Bartosz; Le Cesne, Axel; Van Tine, Brian A.; Trent, Jonathan C.; Patel, Shreyaskumar; Wagner, Andrew J.; Chugh, Rashmi; Heyburn, John W.; Weil, Susan C.; Wang, Wenquan; Viele, Kert; Maki, Robert G. (2019). "A phase 1 and randomized controlled phase 2 trial of the safety and efficacy of the combination of gemcitabine and docetaxel with ontuxizumab (MORAb‐004) in metastatic soft‐tissue sarcomas." Cancer (14): 2445-2454. | |
dc.identifier.issn | 0008-543X | |
dc.identifier.issn | 1097-0142 | |
dc.identifier.uri | https://hdl.handle.net/2027.42/149695 | |
dc.publisher | John Wiley & Sons Inc | |
dc.subject.other | MORAb‐004 | |
dc.subject.other | endosialin | |
dc.subject.other | ontuxizumab | |
dc.subject.other | sarcomas | |
dc.subject.other | tumor endothelial marker 1 (TEM‐1) | |
dc.title | A phase 1 and randomized controlled phase 2 trial of the safety and efficacy of the combination of gemcitabine and docetaxel with ontuxizumab (MORAb‐004) in metastatic soft‐tissue sarcomas | |
dc.type | Article | |
dc.rights.robots | IndexNoFollow | |
dc.subject.hlbsecondlevel | Public Health | |
dc.subject.hlbsecondlevel | Oncology and Hematology | |
dc.subject.hlbtoplevel | Health Sciences | |
dc.description.peerreviewed | Peer Reviewed | |
dc.description.bitstreamurl | https://deepblue.lib.umich.edu/bitstream/2027.42/149695/1/cncr32084_am.pdf | |
dc.description.bitstreamurl | https://deepblue.lib.umich.edu/bitstream/2027.42/149695/2/cncr32084.pdf | |
dc.identifier.doi | 10.1002/cncr.32084 | |
dc.identifier.source | Cancer | |
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dc.identifier.citedreference | Maki RG, Wathen JK, Patel SR, et al. Randomized phase II study of gemcitabine and docetaxel compared with gemcitabine alone in patients with metastatic soft tissue sarcomas: results of Sarcoma Alliance for Research Through Collaboration Study 002. J Clin Oncol. 2007; 25: 2755 ‐ 2763. | |
dc.identifier.citedreference | Rybinski K, Imtiyaz HZ, Mittica B, et al. Targeting endosialin/CD248 through antibody‐mediated internalization results in impaired pericyte maturation and dysfunctional tumor microvasculature. Oncotarget. 2015; 6: 25429 ‐ 25440. | |
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dc.identifier.citedreference | Dickson MA, D’Adamo DR, Keohan ML, et al. Phase II trial of gemcitabine and docetaxel with bevacizumab in soft tissue sarcoma. Sarcoma. 2015; 2015: 532478. | |
dc.identifier.citedreference | Hensley ML, Blessing JA, Degeest K, et al. Fixed‐dose rate gemcitabine plus docetaxel as second‐line therapy for metastatic uterine leiomyosarcoma: a Gynecologic Oncology Group phase II trial. Gynecol Oncol. 2008; 109: 323 ‐ 328. | |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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