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Basal cell carcinoma of the vulva: a case report and systematic review of the literature

dc.contributor.authorRenati, Sruthi
dc.contributor.authorHenderson, Christopher
dc.contributor.authorAluko, Ashley
dc.contributor.authorBurgin, Susan
dc.date.accessioned2019-08-09T17:14:38Z
dc.date.availableWITHHELD_13_MONTHS
dc.date.available2019-08-09T17:14:38Z
dc.date.issued2019-08
dc.identifier.citationRenati, Sruthi; Henderson, Christopher; Aluko, Ashley; Burgin, Susan (2019). "Basal cell carcinoma of the vulva: a case report and systematic review of the literature." International Journal of Dermatology 58(8): 892-902.
dc.identifier.issn0011-9059
dc.identifier.issn1365-4632
dc.identifier.urihttps://hdl.handle.net/2027.42/150570
dc.description.abstractThe vulva is an unusual site for basal cell carcinoma (BCC). Vulvar BCC accounts for <1% of all BCCs and <5% of all vulvar malignancies. We report the case of an 83 year‐old woman who presented with a 2‐month history of a tender labial growth, with histopathology confirming nodular BCC. We conducted a systematic literature review of the characteristics of reported cases of vulvar BCCs. A comprehensive systematic review of articles indexed for MEDLINE and Embase yielded 96 reports describing 437 patients with 446 BCCs of the vulva. The mean age at presentation was 70 (range 20–100). Most women had no underlying vulvar disease. Approximately 60% of cases were of the nodular subtype. Treatment approach varied widely with over half of cases treated with wide local or local excision. Mohs micrographic surgery (MMS) for vulvar BCC was first reported in 1988 with seven total MMS cases reported. Twenty‐three cases of recurrence have been reported; 21 of these cases after local excision but none following MMS. Vulvar BCC is a rarely reported cancer that affects older women predominantly. MMS represents a promising treatment for BCC in this anatomic location.
dc.publisherWiley Periodicals, Inc.
dc.titleBasal cell carcinoma of the vulva: a case report and systematic review of the literature
dc.typeArticle
dc.rights.robotsIndexNoFollow
dc.subject.hlbsecondlevelDermatology
dc.subject.hlbtoplevelHealth Sciences
dc.description.peerreviewedPeer Reviewed
dc.description.bitstreamurlhttps://deepblue.lib.umich.edu/bitstream/2027.42/150570/1/ijd14307.pdf
dc.description.bitstreamurlhttps://deepblue.lib.umich.edu/bitstream/2027.42/150570/2/ijd14307_am.pdf
dc.identifier.doi10.1111/ijd.14307
dc.identifier.sourceInternational Journal of Dermatology
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dc.owningcollnameInterdisciplinary and Peer-Reviewed


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