Low eGFR is associated with dysexecutive and amnestic mild cognitive impairment
dc.contributor.author | Zammit, Andrea R. | |
dc.contributor.author | Katz, Mindy J. | |
dc.contributor.author | Zimmerman, Molly E. | |
dc.contributor.author | Bitzer, Markus | |
dc.contributor.author | Lipton, Richard B. | |
dc.date.accessioned | 2020-01-13T15:04:47Z | |
dc.date.available | 2020-01-13T15:04:47Z | |
dc.date.issued | 2015-06 | |
dc.identifier.citation | Zammit, Andrea R.; Katz, Mindy J.; Zimmerman, Molly E.; Bitzer, Markus; Lipton, Richard B. (2015). "Low eGFR is associated with dysexecutive and amnestic mild cognitive impairment." Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring 1(2): 152-159. | |
dc.identifier.issn | 2352-8729 | |
dc.identifier.issn | 2352-8729 | |
dc.identifier.uri | https://hdl.handle.net/2027.42/152560 | |
dc.description.abstract | BackgroundFew studies have explored the association between renal function and major subtypes of mild cognitive impairment (MCI).MethodsThe sample was from the Einstein Aging Study. The estimated glomerular filtration rate (eGFR, calculated in mL/min/1.73 m2 units) was classified into low (<45), moderate (45–59), and high (≥60). Separate binary logistic regression models were run to determine if eGFR is associated with amnestic MCI (aMCI) and dysexecutive MCI (dMCI).ResultsOf 622 eligible participants 65 (10.5%) had low eGFR, 43 (7.1%) had aMCI, and 46 (7.6) had dMCI. Low eGFR was independently associated with dMCI and aMCI in fully adjusted models.ConclusionAt cross‐section low eGFR is associated with a higher risk of both dMCI and aMCI. eGFR may contribute to the development of these cognitive states directly. Alternatively, low eGFR may be a marker for risk factors that influence both the kidney and the brain, such as coronary microvascular disease. | |
dc.publisher | War Department, Adjutant General’s Office | |
dc.publisher | Wiley Periodicals, Inc. | |
dc.subject.other | Renal function | |
dc.subject.other | Dysexecutive MCI | |
dc.subject.other | Amnestic MCI | |
dc.title | Low eGFR is associated with dysexecutive and amnestic mild cognitive impairment | |
dc.type | Article | |
dc.rights.robots | IndexNoFollow | |
dc.subject.hlbsecondlevel | Neurology and Neurosciences | |
dc.subject.hlbtoplevel | Health Sciences | |
dc.description.peerreviewed | Peer Reviewed | |
dc.description.bitstreamurl | https://deepblue.lib.umich.edu/bitstream/2027.42/152560/1/dad2jdadm201412002.pdf | |
dc.identifier.doi | 10.1016/j.dadm.2014.12.002 | |
dc.identifier.source | Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring | |
dc.identifier.citedreference | A.F. Jorm, P.A. Jacomb. The informant questionnaire on cognitive decline in the elderly (IQCODE): socio‐demographic correlates, reliability, validity and some norms. Psychol Med. 19: 1989; 1015 – 1022 | |
dc.identifier.citedreference | S.L. Seliger, D.S. Siscovick, C.O. Steham‐Breen, D.L. Gillen, A. Fitzpatrick, A. Bleyer, et al. Moderate renal impairment and risk of dementia among older adults: the Cardiovascular Health Cognition Study. J Am Soc Nephrol. 15: 2004; 1904 – 1911 | |
dc.identifier.citedreference | K. Yaffe, L. Ackerson, M. Kurella Tamura, P. Le Blanc, J.W. Kusek, A.R. Sehgal, et al. Chronic kidney disease and cognitive function in older adults: findings from the chronic renal insufficiency cohort cognitive study. J Am Geriatr Soc. 58: 2010; 338 – 345 | |
dc.identifier.citedreference | A.M. Murray, D.S. Knopman. Cognitive impairment in CKD: no longer an occult burden. Am J Kidney Dis. 56: 2010; 615 – 618 | |
dc.identifier.citedreference | J.J. Manly, M.X. Tang, N. Schupf, Y. Stern, J.P.G. Vonsattel, R. Mayeux. Frequency and course of mild cognitive impairment in a multiethnic community. Ann Neurol. 63: 2008; 494 – 506 | |
dc.identifier.citedreference | R.C. Petersen, R.O. Roberts, D.S. Knopman, B.F. Boeve, M.D. Geda, R.J. Ivnik, et al. Mild cognitive impairment: ten years later. Arch Neurol. 66: 2009; 1447 – 1455 | |
dc.identifier.citedreference | J. Pa, A. Boxer, L.L. Chao, A. Gazzaley, K. Freeman, J. Kramer, et al. Clinical‐neuroimaging characteristics of dysexecutive mild cognitive impairment. Ann Neurol. 65: 2009; 414 – 423 | |
dc.identifier.citedreference | A.S. Levey, J.P. Bosch, J. Breyer Lewis, T. Green, N. Rogers, D. Roth. A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. Ann Intern Med. 130: 1999; 461 – 470 | |
dc.identifier.citedreference | M. Cirillo, P. Anastasio, N.G. De Santo. Relationship of gender, age and body mass index to errors in predicting kidney function. Nephrol Dial Transplant. 20: 2005; 1791 – 1798 | |
dc.identifier.citedreference | C. Helmer, B. Stengel, M. Metzger, M. Froissart, Z. Massy, C. Tzourio, et al. Chronic kidney disease, cognitive decline, and incident dementia: the 3C Study. Neurology. 77: 2011; 2043 – 2051 | |
dc.identifier.citedreference | S. Artero, R. Petersen, J. Touchon, K. Ritchie. Revised criteria for mild cognitive impairment: validation within a longitudinal population study. Dement Geriatr Cogn Disord. 22: 2006; 465 – 470 | |
dc.identifier.citedreference | D. Wechsler. Wechsler Memory Scale—Revised. 1987; The Psychological Corporation: San Antonio, Texas | |
dc.identifier.citedreference | H. Buschke. Cued recall in amnesia. J Clin Neuropsychol. 6: 1984; 433 – 440 | |
dc.identifier.citedreference | J.C. Morris, A. Heyman, R.C. Mohs, J.P. Hughes, G. van Belle, G. Fillenbaum, et al. The consortium to establish a registry for Alzheimer’s disease (CERAD). Part I. Clinical and neuropsychological assessment of Alzheimer’s disease. Neurology. 39: 1989; 1159 – 1165 | |
dc.identifier.citedreference | M.P. Lawton, E.M. Brody. Assessment of older people: self‐maintaining and instrumental activities of daily living. Gerontologist. 9: 1969; 179 – 186 | |
dc.identifier.citedreference | J.I. Sheikh, J.A. Yesavage. Geriatric depression scale (GDS); recent evidence and development of a shorter version. Gerontologist. 5: 1986; 165 – 173 | |
dc.identifier.citedreference | M.J. Katz, R.B. Lipton, C.B. Hall, M.E. Zimmerman, A.E. Sanders, J. Verghese, et al. Age‐specific and sex‐specific prevalence and incidence of mild cognitive impairment, dementia, and Alzheimer dementia in blacks and whites: a report from the Einstein Aging Study. Alzheimer Dis Assoc Disord. 26: 2012; 335 – 343 | |
dc.identifier.citedreference | S. Sadigh‐Eteghad, M. Talebi, M. Farhoudi. Association of apolipoprotein E epsilon 4 allele with sporadic late onset Alzheimer’s disease: a meta‐analysis. Neurosciences (Riyadh). 17: 2012; 321 – 326 | |
dc.identifier.citedreference | M.F. Elias, P.K. Elias, S.L. Seliger, S.S. Narsipur, G.A. Dore, M.A. Robbins. Chronic kidney disease, creatinine and cognitive functioning. Nephrol Dial Transplant. 24: 2009; 2446 – 2452 | |
dc.identifier.citedreference | A. Caroli, C. Teast, C. Geroldi, F. Nobili, L.R. Barnden, U. Guerra, et al. Cerebral perfusion correlates of conversion to Alzheimer’s disease in amnestic mild cognitive impairment. J Neurol. 254: 2007; 1698 – 1707 | |
dc.identifier.citedreference | L.J. Launer. Demonstrating the case that AD is a vascular disease: epidemiologic evidence. Ageing Res Rev. 1: 2002; 61 – 77 | |
dc.identifier.citedreference | R. Brookmeyer, S. Gray, C. Kawas. Projections of Alzheimer’s disease in the United States and the public health impact of delaying disease onset. Am J Public Health. 88: 1998; 1337 – 1342 | |
dc.identifier.citedreference | J.C. de la Torre. Vascular risk factor detection and control may prevent Alzheimer’s disease. Ageing Res Rev. 9: 2010; 218 – 225 | |
dc.identifier.citedreference | M. Kurella, G.M. Chertow, J. Luan, K. Yaffe. Cognitive impairment in chronic kidney disease. J Am Geriatr Soc. 52: 2004; 1863 – 1869 | |
dc.identifier.citedreference | M. Kurella, K. Yaffe, M.G. Shlipak, N.K. Wenger, G.M. Chertow. Chronic kidney disease and cognitive impairment in menopausal women. Am J Kidney Dis. 45: 2005; 66 – 76 | |
dc.identifier.citedreference | W.L. Thornton, R.J. Shapiro, S. Deria, S. Gelb, A. Hill. Differential impact of age on verbal memory and executive functioning in chronic kidney disease. J Int Neuropsychol Soc. 13: 2007; 344 – 353 | |
dc.identifier.citedreference | Y. Slinin, M.L. Paudel, A. Ishani, B.C. Taylor, K. Yaffe, A.M. Murray, et al. Kidney function and cognitive performance and decline in older men. J Am Geriatr Soc. 56: 2008; 2082 – 2088 | |
dc.identifier.citedreference | Army Individual Test Battery Manual of directions and scoring. 1944; War Department, Adjutant General’s Office: Washington, DC | |
dc.identifier.citedreference | D. Wechsler. Wechsler Adult Intelligence Scale—Third Edition. 1997; The Psychological Corporation: New York | |
dc.identifier.citedreference | Zammit, AR, Katz, MJ, Lai, JY, Zimmerman, ME, Bitzer, M, Lipton, RB. Renal function and cognitive composites of function in the Einstein Aging Study: a cross‐sectional analysis, in press. J Gerontol Med Sci. | |
dc.identifier.citedreference | R.C. Petersen, R. Doody, A. Kurz, R.C. Mohs, J.C. Morris, P.V. Rabbins, et al. Current concepts in mild cognitive impairment. JAMA. 58: 2001; 1985 – 1992 | |
dc.identifier.citedreference | E.D. Huey, J.J. Manly, M.X. Tang, N. Schupf, A.M. Brickman, M. Manoochehri, et al. Course and etiology of dysexecutive MCI in a community sample. Alzheimers Dement. 9: 2003; 632 – 639 | |
dc.identifier.citedreference | J.B. Post, A.B. Jegede, K. Morin, A.M. Spungen, E. Langhoff, M. Sano. Cognitive profile of chronic kidney disease and hemodialysis patients without dementia. Nephron Clin Pract. 116: 2010; c247 – c255 | |
dc.identifier.citedreference | K. Griva, J. Stygall, M. Hankins, A. Davenport, M. Harrison, S.P. Newman. Cognitive impairment and 7‐year mortality in dialysis patients. Am J Kidney Dis. 56: 2010; 693 – 703 10.1053/j.ajkd.2010.07.003 | |
dc.identifier.citedreference | S. Sánchez‐Román, F. Ostrosky‐Solís, L.E. Morales‐Buenrostro, M.G. Nogués‐Vizcaíno, J. Alberú, S.M. McClintock. Neurocognitive profile of an adult sample with chronic kidney disease. J Int Neuropsychol Soc. 17: 2011; 80 – 90 | |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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