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Attachment of Reporter and Conjugate Groups to the 3′ Termini of Oligonucleotides
dc.contributor.authorGreenberg, Marc M.
dc.date.accessioned2020-01-13T15:09:12Z
dc.date.available2020-01-13T15:09:12Z
dc.date.issued2000-10
dc.identifier.citationGreenberg, Marc M. (2000). "Attachment of Reporter and Conjugate Groups to the 3′ Termini of Oligonucleotides." Current Protocols in Nucleic Acid Chemistry 2(1): 4.5.1-4.5.19.
dc.identifier.issn1934-9270
dc.identifier.issn1934-9289
dc.identifier.urihttps://hdl.handle.net/2027.42/152752
dc.description.abstractConjugation of oligonucleotides at the 3 terminus is less common because this site is used for covalent linkage to solid‐phase oligonucleotide synthesis supports. However, 3‐oligonucleotide conjugates have several valuable physicochemical properties, including their ability to stabilize nucleic acid hybridization complexes and to retard the activity of exonucleases. This unit discusses methods for preparing oligonucleotides conjugated at the 3 terminus.
dc.publisherWiley Periodicals, Inc.
dc.publisherHumana Press
dc.titleAttachment of Reporter and Conjugate Groups to the 3′ Termini of Oligonucleotides
dc.typeArticle
dc.rights.robotsIndexNoFollow
dc.subject.hlbsecondlevelBiological Chemistry
dc.subject.hlbsecondlevelChemical Engineering
dc.subject.hlbsecondlevelChemistry
dc.subject.hlbsecondlevelPublic Health
dc.subject.hlbtoplevelHealth Sciences
dc.subject.hlbtoplevelEngineering
dc.subject.hlbtoplevelScience
dc.description.peerreviewedPeer Reviewed
dc.description.bitstreamurlhttps://deepblue.lib.umich.edu/bitstream/2027.42/152752/1/cpnc0405.pdf
dc.identifier.doi10.1002/0471142700.nc0405s02
dc.identifier.sourceCurrent Protocols in Nucleic Acid Chemistry
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dc.owningcollnameInterdisciplinary and Peer-Reviewed


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