Imbalance of Hsp70 family variants fosters tau accumulation
dc.contributor.author | Jinwal, Umesh K. | |
dc.contributor.author | Akoury, Elias | |
dc.contributor.author | Abisambra, Jose F. | |
dc.contributor.author | O’Leary, John C. | |
dc.contributor.author | Thompson, Andrea D. | |
dc.contributor.author | Blair, Laura J. | |
dc.contributor.author | Jin, Ying | |
dc.contributor.author | Bacon, Justin | |
dc.contributor.author | Nordhues, Bryce A. | |
dc.contributor.author | Cockman, Matthew | |
dc.contributor.author | Zhang, Juan | |
dc.contributor.author | Li, Pengfei | |
dc.contributor.author | Zhang, Bo | |
dc.contributor.author | Borysov, Sergiy | |
dc.contributor.author | Uversky, Vladimir N. | |
dc.contributor.author | Biernat, Jacek | |
dc.contributor.author | Mandelkow, Eckhard | |
dc.contributor.author | Gestwicki, Jason E. | |
dc.contributor.author | Zweckstetter, Markus | |
dc.contributor.author | Dickey, Chad A. | |
dc.date.accessioned | 2020-03-17T18:31:25Z | |
dc.date.available | 2020-03-17T18:31:25Z | |
dc.date.issued | 2013-04 | |
dc.identifier.citation | Jinwal, Umesh K.; Akoury, Elias; Abisambra, Jose F.; O’Leary, John C.; Thompson, Andrea D.; Blair, Laura J.; Jin, Ying; Bacon, Justin; Nordhues, Bryce A.; Cockman, Matthew; Zhang, Juan; Li, Pengfei; Zhang, Bo; Borysov, Sergiy; Uversky, Vladimir N.; Biernat, Jacek; Mandelkow, Eckhard; Gestwicki, Jason E.; Zweckstetter, Markus; Dickey, Chad A. (2013). "Imbalance of Hsp70 family variants fosters tau accumulation." The FASEB Journal 27(4): 1450-1459. | |
dc.identifier.issn | 0892-6638 | |
dc.identifier.issn | 1530-6860 | |
dc.identifier.uri | https://hdl.handle.net/2027.42/154405 | |
dc.publisher | Federation of American Societies for Experimental Biology | |
dc.publisher | Wiley Periodicals, Inc. | |
dc.subject.other | CHIP | |
dc.subject.other | Hsc70 | |
dc.subject.other | Alzheimer’s | |
dc.subject.other | Hsp72 | |
dc.subject.other | chaperones | |
dc.title | Imbalance of Hsp70 family variants fosters tau accumulation | |
dc.type | Article | |
dc.rights.robots | IndexNoFollow | |
dc.subject.hlbsecondlevel | Biology | |
dc.subject.hlbtoplevel | Science | |
dc.description.peerreviewed | Peer Reviewed | |
dc.description.bitstreamurl | https://deepblue.lib.umich.edu/bitstream/2027.42/154405/1/fsb2027004018.pdf | |
dc.identifier.doi | 10.1096/fj.12-220889 | |
dc.identifier.source | The FASEB Journal | |
dc.identifier.citedreference | Ballinger, C. A., Connell, P., Wu, Y., Hu, Z., Thompson, L. J., Yin, L. Y., and Patterson, C. ( 1999 ) Identification of CHIP, a novel tetratricopeptide repeat‐containing protein that interacts with heat shock proteins and negatively regulates chaperone functions. Mol. Cell. Biol. 19, 4535 – 4545 | |
dc.identifier.citedreference | Dou, F., Netzer, W. J., Tanemura, K., Li, F., Hartl, F. U., Takashima, A., Gouras, G. K., Greengard, P., and Xu, H. ( 2003 ) Chaperones increase association of tau protein with microtubules. Proc. Natl. Acad. Sci. U. S. A. 100, 721 – 726 | |
dc.identifier.citedreference | Koren, J., 3rd, Miyata, Y., Kiray, J., O’Leary, J. C., 3rd, Nguyen, L., Guo, J., Blair, L. J., Li, X., Jinwal, U. K., Cheng, J. Q., Gestwicki, J. E., and Dickey, C. A. ( 2012 ) Rhodacyanine derivative selectively targets cancer cells and overcomes tamoxifen resistance. PloS ONE 7, e35566 | |
dc.identifier.citedreference | Goldfarb, S. B., Kashlan, O. B., Watkins, J. N., Suaud, L., Yan, W., Kleyman, T. R., and Rubenstein, R. C. ( 2006 ) Differential effects of Hsc70 and Hsp70 on the intracellular trafficking and functional expression of epithelial sodium channels. Proc. Natl Acad. Sci. U. S. A. 103, 5817 – 5822 | |
dc.identifier.citedreference | Black, M. M., Chestnut, M. H., Pleasure, I. T., and Keen, J. H. ( 1991 ) Stable clathrin: uncoating protein (Hsc70) complexes in intact neurons and their axonal transport. J. Neurosci. 11, 1163 – 1172 | |
dc.identifier.citedreference | Williams, G. T., and Morimoto, R. I. ( 1990 ) Maximal stress‐induced transcription from the human HSP70 promoter requires interactions with the basal promoter elements independent of rotational alignment. Mol. Cell. Biol. 10, 3125 – 3136 | |
dc.identifier.citedreference | Tavaria, M., Gabriele, T., Kola, I., and Anderson, R. L. ( 1996 ) A hitchhiker’s guide to the human Hsp70 family. Cell Stress Chaperones 1, 23 – 28 | |
dc.identifier.citedreference | Qian, S. B., McDonough, H., Boellmann, F., Cyr, D. M., and Patterson, C. ( 2006 ) CHIP‐mediated stress recovery by sequential ubiquitination of substrates and Hsp70. Nature 440, 551 – 555 | |
dc.identifier.citedreference | Jinwal, U. K., Koren, J., 3rd, Borysov, S. I., Schmid, A. B., Abisambra, J. F., Blair, L. J., Johnson, A. G., Jones, J. R., Shults, C. L., O’Leary, J. C., 3rd, Jin, Y., Buchner, J., Cox, M. B., and Dickey, C. A. ( 2010 ) The Hsp90 cochaperone, FKBP51, increases Tau stability and polymerizes microtubules. J. Neurosci. 30, 591 – 599 | |
dc.identifier.citedreference | O’Leary, J. C., 3rd, Li, Q., Marinec, P., Blair, L. J., Congdon, E. E., Johnson, A. G., Jinwal, U. K., Koren, J., 3rd, Jones, J. R., Kraft, C., Peters, M., Abisambra, J. F., Duff, K. E., Weeber, E. J., Gestwicki, J. E., and Dickey, C. A. ( 2010 ) Phenothiazine‐mediated rescue of cognition in tau transgenic mice requires neuroprotection and reduced soluble tau burden. Mol. Neurodegener. 5, 45 | |
dc.identifier.citedreference | Dickey, C., Kraft, C., Jinwal, U., Koren, J., Johnson, A., Anderson, L., Lebson, L., Lee, D., Dickson, D., de Silva, R., Binder, L. I., Morgan, D., and Lewis, J. ( 2009 ) Aging analysis reveals slowed tau turnover and enhanced stress response in a mouse model of tauopathy. Am. J. Pathol. 174, 228 – 238 | |
dc.identifier.citedreference | Desai, A., Verma, S., Mitchison, T. J., and Walczak, C. E. ( 1999 ) Kin I kinesins are microtubule‐destabilizing enzymes. Cell 96, 69 – 78 | |
dc.identifier.citedreference | Budde, P. P., Desai, A., and Heald, R. ( 2006 ) Analysis of microtubule polymerization in vitro and during the cell cycle in Xenopus egg extracts. Methods 38, 29 – 34 | |
dc.identifier.citedreference | Mukrasch, M. D., Biernat, J., von Bergen, M., Griesinger, C., Mandelkow, E., and Zweckstetter, M. ( 2005 ) Sites of tau important for aggregation populate β‐structure and bind to microtubules and polyanions. J. Biol. Chem. 280, 24978 – 24986 | |
dc.identifier.citedreference | Delaglio, F., Grzesiek, S., Vuister, G. W., Zhu, G., Pfeifer, J., and Bax, A. ( 1995 ) NMRPipe: a multidimensional spectral processing system based on UNIX pipes. J. Biomol. NMR 6, 277 – 293 | |
dc.identifier.citedreference | Vranken, W. F., Boucher, W., Stevens, T. J., Fogh, R. H., Pajon, A., Llinas, M., Ulrich, E. L., Markley, J. L., Ionides, J., and Laue, E. D. ( 2005 ) The CCPN data model for NMR spectroscopy: development of a software pipeline. Proteins 59, 687 – 696 | |
dc.identifier.citedreference | Abisambra, J. F., Blair, L. J., Hill, S. E., Jones, J. R., Kraft, C., Rogers, J., Koren, J., 3rd, Jinwal, U. K., Lawson, L., Johnson, A. G., Wilcock, D., O’Leary, J. C., Jansen‐West, K., Muschol, M., Golde, T. E., Weeber, E. J., Banko, J., and Dickey, C. A. ( 2010 ) Phosphorylation dynamics regulate Hsp27‐mediated rescue of neuronal plasticity deficits in tau transgenic mice. J. Neurosci. 30, 15374 – 15382 | |
dc.identifier.citedreference | Ricci, L., and Williams, K. P. ( 2008 ) Development of fluorescence polarization assays for the molecular chaperone Hsp70 family members: Hsp72 and DnaK. Curr. Chem. Genomics 2, 90 – 95 | |
dc.identifier.citedreference | Westerheide, S. D., Bosman, J. D., Mbadugha, B. N., Kawahara, T. L., Matsumoto, G., Kim, S., Gu, W., Devlin, J. P., Silverman, R. B., and Morimoto, R. I. ( 2004 ) Celastrols as inducers of the heat shock response and cytoprotection. J. Biol. Chem. 279, 56053 – 56060 | |
dc.identifier.citedreference | Jo, H., Loison, F., Hattori, H., Silberstein, L. E., Yu, H., and Luo, H. R. ( 2010 ) Natural product Celastrol destabilizes tubulin heterodimer and facilitates mitotic cell death triggered by microtubule‐targeting anti‐cancer drugs. PloS ONE 5, e10318 | |
dc.identifier.citedreference | Wang, Y., Martinez‐Vicente, M., Kruger, U., Kaushik, S., Wong, E., Mandelkow, E. M., Cuervo, A. M., and Mandelkow, E. ( 2009 ) Tau fragmentation, aggregation and clearance: the dual role of lysosomal processing. Hum. Mol. Genet. 18, 4153 – 4170 | |
dc.identifier.citedreference | Sarkar, M., Kuret, J., and Lee, G. ( 2008 ) Two motifs within the tau microtubule‐binding domain mediate its association with the hsc70 molecular chaperone. J. Neurosci. Res. 86, 2763 – 2773 | |
dc.identifier.citedreference | Dolan, P. J., and Johnson, G. V. ( 2010 ) A caspase cleaved form of tau is preferentially degraded through the autophagy pathway. J. Biol. Chem. 285, 21978 – 21987 | |
dc.identifier.citedreference | Rudiger, S., Buchberger, A., and Bukau, B. ( 1997 ) Interaction of Hsp70 chaperones with substrates. Nat. Struc. Biol. 4, 342 – 349 | |
dc.identifier.citedreference | Zhu, X., Zhao, X., Burkholder, W. F., Gragerov, A., Ogata, C. M., Gottesman, M. E., and Hendrickson, W. A. ( 1996 ) Structural analysis of substrate binding by the molecular chaperone DnaK. Science 272, 1606 – 1614 | |
dc.identifier.citedreference | Sahara, N., Murayama, M., Mizoroki, T., Urushitani, M., Imai, Y., Takahashi, R., Murata, S., Tanaka, K., and Takashima, A. ( 2005 ) In vivo evidence of CHIP up‐regulation attenuating tau aggregation. J. Neurochem. 94, 1254 – 1263 | |
dc.identifier.citedreference | Hammond, G. L., Lai, Y. K., and Markert, C. L. ( 1982 ) Diverse forms of stress lead to new patterns of gene expression through a common and essential metabolic pathway. Proc. Natl. Acad. Sci. U. S. A. 79, 3485 – 3488 | |
dc.identifier.citedreference | Fawcett, T. W., Sylvester, S. L., Sarge, K. D., Morimoto, R. I., and Holbrook, N. J. ( 1994 ) Effects of neurohormonal stress and aging on the activation of mammalian heat shock factor 1. J. Biol. Chem. 269, 32272 – 32278 | |
dc.identifier.citedreference | Heydari, A. R., Wu, B., Takahashi, R., Strong, R., and Richardson, A. ( 1993 ) Expression of heat shock protein 70 is altered by age and diet at the level of transcription. Mol. Cell. Biol. 13, 2909 – 2918 | |
dc.identifier.citedreference | Von Bergen, M., Friedhoff, P., Biernat, J., Heberle, J., Mandelkow, E. M., and Mandelkow, E. ( 2000 ) Assembly of tau protein into Alzheimer paired helical filaments depends on a local sequence motif ((306)VQIVYK(311)) forming beta structure. Proc. Natl. Acad. Sci. U. S. A. 97, 5129 – 5134 | |
dc.identifier.citedreference | Von Bergen, M., Barghorn, S., Li, L., Marx, A., Biernat, J., Mandelkow, E. M., and Mandelkow, E. ( 2001 ) Mutations of tau protein in frontotemporal dementia promote aggregation of paired helical filaments by enhancing local beta‐structure. J. Biol. Chem. 276, 48165 – 48174 | |
dc.identifier.citedreference | Goldschmidt, L., Teng, P. K., Riek, R., and Eisenberg, D. ( 2010 ) Identifying the amylome, proteins capable of forming amyloidlike fibrils. Proc. Natl. Acad. Sci. U. S. A. 107, 3487 – 3492 | |
dc.identifier.citedreference | Song, Y., Wu, Y. X., Jung, G., Tutar, Y., Eisenberg, E., Greene, L. E., and Masison, D. C. ( 2005 ) Role for Hsp70 chaperone in Saccharomyces cerevisiae prion seed replication. Eukaryot. Cell 4, 289 – 297 | |
dc.identifier.citedreference | Eisenberg, D., Nelson, R., Sawaya, M. R., Balbirnie, M., Sambashivan, S., Ivanova, M. I., Madsen, A. O., and Riekel, C. ( 2006 ) The structural biology of protein aggregation diseases: fundamental questions and some answers. Acc. Chem. Res. 39, 568 – 575 | |
dc.identifier.citedreference | Cuervo, A. M., and Dice, J. F. ( 1996 ) A receptor for the selective uptake and degradation of proteins by lysosomes. Science 273, 501 – 503 | |
dc.identifier.citedreference | Dickey, C. A., Dunmore, J., Lu, B., Wang, J. W., Lee, W. C., Kamal, A., Burrows, F., Eckman, C., Hutton, M., and Petrucelli, L. ( 2006 ) HSP induction mediates selective clearance of tau phosphorylated at proline‐directed Ser/Thr sites but not KXGS (MARK) sites. FASEB J. 20, 753 – 755 | |
dc.identifier.citedreference | Dickey, C. A., Kamal, A., Lundgren, K., Klosak, N., Bailey, R. M., Dunmore, J., Ash, P., Shoraka, S., Zlatkovic, J., Eckman, C. B., Patterson, C., Dickson, D. W., Nahman, N. S., Jr., Hutton, M., Burrows, F., and Petrucelli, L. ( 2007 ) The high‐affinity HSP90‐CHIP complex recognizes and selectively degrades phosphorylated tau client proteins. J. Clin. Invest. 117, 648 – 658 | |
dc.identifier.citedreference | Jinwal, U. K., Miyata, Y., Koren, J., 3rd, Jones, J. R., Trotter, J. H., Chang, L., O’Leary, J., Morgan, D., Lee, D. C., Shults, C. L., Rousaki, A., Weeber, E. J., Zuiderweg, E. R., Gestwicki, J. E., and Dickey, C. A. ( 2009 ) Chemical manipulation of hsp70 ATPase activity regulates tau stability. J. Neurosci. 29, 12079 – 12088 | |
dc.identifier.citedreference | Drewes, G., Ebneth, A., Preuss, U., Mandelkow, E. M., and Mandelkow, E. ( 1997 ) MARK, a novel family of protein kinases that phosphorylate microtubule‐associated proteins and trigger microtubule disruption. Cell 89, 297 – 308 | |
dc.identifier.citedreference | Li, X., Kumar, Y., Zempel, H., Mandelkow, E. M., Biernat, J., and Mandelkow, E. ( 2011 ) Novel diffusion barrier for axonal retention of Tau in neurons and its failure in neurodegeneration. EMBO J. 30, 4825 – 4837 | |
dc.identifier.citedreference | Jinwal, U. K., O’Leary, J. C., 3rd, Borysov, S. I., Jones, J. R., Li, Q., Koren, J., 3rd, Abisambra, J. F., Vestal, G. D., Lawson, L. Y., Johnson, A. G., Blair, L. J., Jin, Y., Miyata, Y., Gestwicki, J. E., and Dickey, C. A. ( 2010 ) Hsc70 rapidly engages tau after microtubule destabilization. J. Biol. Chem. 285, 16798 – 16805 | |
dc.identifier.citedreference | Ebneth, A., Godemann, R., Stamer, K., Illenberger, S., Trinczek, B., and Mandelkow, E. ( 1998 ) Overexpression of tau protein inhibits kinesin‐dependent trafficking of vesicles, mitochondria, and endoplasmic reticulum: implications for Alzheimer’s disease. J. Cell Biol. 143, 777 – 794 | |
dc.identifier.citedreference | Mattson, M. P. ( 1992 ) Effects of microtubule stabilization and destabilization on tau immunoreactivity in cultured hippocampal neurons. Brain Res. 582, 107 – 118 | |
dc.identifier.citedreference | Brion, J. P., Octave, J. N., and Couck, A. M. ( 1994 ) Distribution of the phosphorylated microtubule‐associated protein tau in developing cortical neurons. Neuroscience 63, 895 – 909 | |
dc.identifier.citedreference | Petrucelli, L., Dickson, D., Kehoe, K., Taylor, J., Snyder, H., Grover, A., De Lucia, M., McGowan, E., Lewis, J., Prihar, G., Kim, J., Dillmann, W. H., Browne, S. E., Hall, A., Voellmy, R., Tsuboi, Y., Dawson, T. M., Wolozin, B., Hardy, J., and Hutton, M. ( 2004 ) CHIP and Hsp70 regulate tau ubiquitination, degradation and aggregation. Hum. Mol. Genet. 13, 703 – 714 | |
dc.identifier.citedreference | Dickey, C. A., Yue, M., Lin, W. L., Dickson, D. W., Dunmore, J. H., Lee, W. C., Zehr, C., West, G., Cao, S., Clark, A. M., Caldwell, G. A., Caldwell, K. A., Eckman, C., Patterson, C., Hutton, M., and Petrucelli, L. ( 2006 ) Deletion of the ubiquitin ligase CHIP leads to the accumulation, but not the aggregation, of both endogenous phospho‐ and caspase‐3‐cleaved tau species. J. Neurosci. 26, 6985 – 6996 | |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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