Optimization of percutaneous biopsy for diagnosis and pretreatment risk assessment of neuroblastoma
dc.contributor.author | Overman, Richard E. | |
dc.contributor.author | Kartal, Tanvi T. | |
dc.contributor.author | Cunningham, Aaron J. | |
dc.contributor.author | Fialkowski, Elizabeth A. | |
dc.contributor.author | Naik‐mathuria, Bindi J. | |
dc.contributor.author | Vasudevan, Sanjeev A. | |
dc.contributor.author | Malek, Marcus M. | |
dc.contributor.author | Kalsi, Ranjeet | |
dc.contributor.author | Le, Hau D. | |
dc.contributor.author | Stafford, Linda Cherney | |
dc.contributor.author | Lautz, Timothy B. | |
dc.contributor.author | Many, Benjamin T. | |
dc.contributor.author | Jones, Rachel E. | |
dc.contributor.author | Bütter, Andreana | |
dc.contributor.author | Davidson, Jacob | |
dc.contributor.author | Williams, Andrew | |
dc.contributor.author | Dasgupta, Roshni | |
dc.contributor.author | Lewis, Jana | |
dc.contributor.author | Troutt, Misty | |
dc.contributor.author | Aldrink, Jennifer H. | |
dc.contributor.author | Mansfield, Sara A. | |
dc.contributor.author | Lal, Dave R. | |
dc.contributor.author | Xiao, Jerry | |
dc.contributor.author | Meyers, Rebecka L. | |
dc.contributor.author | Short, Scott S. | |
dc.contributor.author | Newman, Erika A. | |
dc.date.accessioned | 2020-04-02T18:39:56Z | |
dc.date.available | WITHHELD_14_MONTHS | |
dc.date.available | 2020-04-02T18:39:56Z | |
dc.date.issued | 2020-05 | |
dc.identifier.citation | Overman, Richard E.; Kartal, Tanvi T.; Cunningham, Aaron J.; Fialkowski, Elizabeth A.; Naik‐mathuria, Bindi J. ; Vasudevan, Sanjeev A.; Malek, Marcus M.; Kalsi, Ranjeet; Le, Hau D.; Stafford, Linda Cherney; Lautz, Timothy B.; Many, Benjamin T.; Jones, Rachel E.; Bütter, Andreana ; Davidson, Jacob; Williams, Andrew; Dasgupta, Roshni; Lewis, Jana; Troutt, Misty; Aldrink, Jennifer H.; Mansfield, Sara A.; Lal, Dave R.; Xiao, Jerry; Meyers, Rebecka L.; Short, Scott S.; Newman, Erika A. (2020). "Optimization of percutaneous biopsy for diagnosis and pretreatment risk assessment of neuroblastoma." Pediatric Blood & Cancer 67(5): n/a-n/a. | |
dc.identifier.issn | 1545-5009 | |
dc.identifier.issn | 1545-5017 | |
dc.identifier.uri | https://hdl.handle.net/2027.42/154667 | |
dc.description.abstract | BackgroundImage- guided percutaneous core needle biopsy (PCNB) is increasingly utilized to diagnose solid tumors. The objective of this study is to determine whether PCNB is adequate for modern biologic characterization of neuroblastoma.ProcedureA multi- institutional retrospective study was performed by the Pediatric Surgical Oncology Research Collaborative on children with neuroblastoma at 12 institutions over a 3- year period. Data collected included demographics, clinical details, biopsy technique, complications, and adequacy of biopsies for cytogenetic markers utilized by the Children’s Oncology Group for risk stratification.ResultsA total of 243 children were identified with a diagnosis of neuroblastoma: 79 (32.5%) tumor excision at diagnosis, 94 (38.7%) open incisional biopsy (IB), and 70 (28.8%) PCNB. Compared to IB, there was no significant difference in ability to accurately obtain a primary diagnosis by PCNB (95.7%Â vs 98.9%, PÂ =Â .314) or determine MYCN copy number (92.4%Â vs 97.8%, PÂ =Â .111). The yield for loss of heterozygosity and tumor ploidy was lower with PCNB versus IB (56.1%Â vs 90.9%, PÂ <Â .05; and 58.0%Â vs. 88.5%, PÂ <Â .05). Complications did not differ between groups (2.9 % vs 3.3%, PÂ =Â 1.000), though the PCNB group had fewer blood transfusions and lower opioid usage. Efficacy of PCNB was improved for loss of heterozygosity when a pediatric pathologist evaluated the fresh specimen for adequacy.ConclusionsPCNB is a less invasive alternative to open biopsy for primary diagnosis and MYCN oncogene status in patients with neuroblastoma. Our data suggest that PCNB could be optimized for complete genetic analysis by standardized protocols and real- time pathology assessment of specimen quality. | |
dc.publisher | Wiley Periodicals, Inc. | |
dc.subject.other | percutaneous biopsy | |
dc.subject.other | surgery | |
dc.subject.other | neuroblastoma | |
dc.subject.other | neuroblastoma biology | |
dc.subject.other | tumor biology | |
dc.subject.other | solid tumors | |
dc.title | Optimization of percutaneous biopsy for diagnosis and pretreatment risk assessment of neuroblastoma | |
dc.type | Article | |
dc.rights.robots | IndexNoFollow | |
dc.subject.hlbsecondlevel | Pediatrics | |
dc.subject.hlbtoplevel | Health Sciences | |
dc.description.peerreviewed | Peer Reviewed | |
dc.description.bitstreamurl | https://deepblue.lib.umich.edu/bitstream/2027.42/154667/1/pbc28153_am.pdf | |
dc.description.bitstreamurl | https://deepblue.lib.umich.edu/bitstream/2027.42/154667/2/pbc28153.pdf | |
dc.identifier.doi | 10.1002/pbc.28153 | |
dc.identifier.source | Pediatric Blood & Cancer | |
dc.identifier.citedreference | Monclair T, Brodeur GM, Ambros PF, et al. The International Neuroblastoma Risk Group (INRG) staging system: an INRG Task Force report. J Clin Oncol. 2009; 27 ( 2 ): 298 - 303. | |
dc.identifier.citedreference | Kim J, Sun Z, Adam MA, et al. Predictors of nodal metastasis in pediatric differentiated thyroid cancer. J Pediatr Surg. 2017; 52 ( 1 ): 120 - 123. | |
dc.identifier.citedreference | Newman EA, Abdessalam S, Aldrink JH, et al. Update on neuroblastoma. Neuroblastoma; neuroblastoma biology; tumor biology; surgery; solid tumors; percutaneous biopsy. J Pediatr Surg. 2019; 54 ( 3 ): 383 - 389. | |
dc.identifier.citedreference | López- Terrada D, Alaggio R, De Dávila MT, et al. Towards an international pediatric liver tumor consensus classification: proceedings of the Los Angeles COG liver tumors symposium. Mod Pathol. 2014; 27 ( 3 ): 472 - 491. | |
dc.identifier.citedreference | Lim IIP, Bondoc AJ, Geller JI, Tiao GM. Hepatoblastoma- the evolution of biology, surgery, and transplantation. Children. 2018; 6 ( 1 ): 1. | |
dc.identifier.citedreference | Schleiermacher G, Janoueix- Lerosey I, Ribeiro A, et al. Accumulation of segmental alterations determines progression in neuroblastoma. J Clin Oncol. 2010; 28 ( 19 ): 3122 - 3130. | |
dc.identifier.citedreference | Riley RD, Heney D, Jones DR, et al. A systematic review of molecular and biological tumor markers in neuroblastoma. Clin Cancer Res. 2004; 10 ( 1 Pt 1 ): 4 - 12. | |
dc.identifier.citedreference | Harris PA, Thielke R, Gonzalez N, Conde JG, Taylor R, Payne J. Research electronic data capture (REDCap)- a metadata- driven methodology and workflow process for providing translational research informatics support. J Biomed Inform. 2008; 42 ( 2 ): 377 - 381. | |
dc.identifier.citedreference | Sklair- Levy M, Lebensart PD, Applbaum YH, et al. Percutaneous image- guided needle biopsy in children: summary of our experience with 57 children. Pediatr Radiol. 2001; 31 ( 10 ): 732 - 736. | |
dc.identifier.citedreference | Metz T, Heider A, Vellody R, et al. Image- guided percutaneous core needle biopsy of soft- tissue masses in the pediatric population. Pediatr Radiol. 2016; 46 ( 8 ): 1173 - 1178. | |
dc.identifier.citedreference | Hoffer A, Chung T, Diller L, Kozakewich H, Fletcher A, Shamberger C. Percutaneous biopsy for prognostic testing of neuroblastoma. Radiology. 1996; 200: 213 - 216. | |
dc.identifier.citedreference | Gupta A, Kumar A, Walters S, Chait P, Irwin MS, Gerstle JT. Analysis of needle versus open biopsy for the diagnosis of advanced stage pediatric neuroblastoma. Pediatr Blood Cancer. 2006; 47 ( 7 ): 875 - 879. | |
dc.identifier.citedreference | Campagna G, Rosenfeld E, Foster J, et al. Evolving biopsy techniques for the diagnosis of neuroblastoma in children. J Pediatr Surg. 2018; 53 ( 11 ): 2235 - 2239. | |
dc.identifier.citedreference | Hassan SF, Mathur S, Magliaro TJ, et al. Needle core vs open biopsy for diagnosis of intermediate- and high- risk neuroblastoma in children. J Pediatr Surg. 2012; 47 ( 6 ): 1261 - 1266. | |
dc.identifier.citedreference | Mullassery D, Sharma V, Salim A, et al. Open versus needle biopsy in diagnosing neuroblastoma. J Pediatr Surg. 2014; 49 ( 10 ): 1505 - 1507. | |
dc.identifier.citedreference | Simon T, Matthay KK, Castel V, et al. The International Neuroblastoma Risk Group (INRG) classification System: an INRG Task Force report. J Clin Oncol. 2008; 27 ( 2 ): 289 - 297. | |
dc.identifier.citedreference | Weldon CB, Madenci AL, Tiao GM, et al. Evaluation of the diagnostic biopsy approach for children with hepatoblastoma: a report from the Children’s Oncology Group AHEP 0731 Liver Tumor Committee. J Pediatr Surg. 2019. https://doi:10.1016/j.jpedsurg.2019.05.004. | |
dc.identifier.citedreference | Pohlig F, Kirchhoff C, Lenze U, et al. Percutaneous core needle biopsy versus open biopsy in diagnostics of bone and soft tissue sarcoma: a retrospective study. Eur J Med Res. 2012; 17 ( 1 ): 29. | |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
Files in this item
Remediation of Harmful Language
The University of Michigan Library aims to describe library materials in a way that respects the people and communities who create, use, and are represented in our collections. Report harmful or offensive language in catalog records, finding aids, or elsewhere in our collections anonymously through our metadata feedback form. More information at Remediation of Harmful Language.
Accessibility
If you are unable to use this file in its current format, please select the Contact Us link and we can modify it to make it more accessible to you.