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Prospective cohort study of influenza vaccine effectiveness among healthcare personnel in Lima, Peru: Estudio Vacuna de Influenza Peru, 2016- 2018

dc.contributor.authorWesley, Meredith G.
dc.contributor.authorSoto, Giselle
dc.contributor.authorArriola, Carmen Sofia
dc.contributor.authorGonzales, Miriam
dc.contributor.authorNewes‐adeyi, Gabriella
dc.contributor.authorRomero, Candice
dc.contributor.authorVeguilla, Vic
dc.contributor.authorLevine, Min Z.
dc.contributor.authorSilva, Maria
dc.contributor.authorFerdinands, Jill M.
dc.contributor.authorDawood, Fatimah S.
dc.contributor.authorReynolds, Sue B.
dc.contributor.authorHirsch, Avital
dc.contributor.authorKatz, Mark
dc.contributor.authorMatos, Eduardo
dc.contributor.authorTicona, Eduardo
dc.contributor.authorCastro, Juan
dc.contributor.authorCastillo, Maria
dc.contributor.authorBravo, Eduar
dc.contributor.authorCheung, Angela
dc.contributor.authorPhadnis, Rachel
dc.contributor.authorMartin, Emily Toth
dc.contributor.authorTinoco, Yeny
dc.contributor.authorNeyra Quijandria, Joan Manuel
dc.contributor.authorAzziz‐baumgartner, Eduardo
dc.contributor.authorThompson, Mark G.
dc.contributor.authorSambhara, Suryaprakash
dc.date.accessioned2020-07-02T20:34:02Z
dc.date.availableWITHHELD_13_MONTHS
dc.date.available2020-07-02T20:34:02Z
dc.date.issued2020-07
dc.identifier.citationWesley, Meredith G.; Soto, Giselle; Arriola, Carmen Sofia; Gonzales, Miriam; Newes‐adeyi, Gabriella ; Romero, Candice; Veguilla, Vic; Levine, Min Z.; Silva, Maria; Ferdinands, Jill M.; Dawood, Fatimah S.; Reynolds, Sue B.; Hirsch, Avital; Katz, Mark; Matos, Eduardo; Ticona, Eduardo; Castro, Juan; Castillo, Maria; Bravo, Eduar; Cheung, Angela; Phadnis, Rachel; Martin, Emily Toth; Tinoco, Yeny; Neyra Quijandria, Joan Manuel; Azziz‐baumgartner, Eduardo ; Thompson, Mark G.; Sambhara, Suryaprakash (2020). "Prospective cohort study of influenza vaccine effectiveness among healthcare personnel in Lima, Peru: Estudio Vacuna de Influenza Peru, 2016- 2018." Influenza and Other Respiratory Viruses 14(4): 391-402.
dc.identifier.issn1750-2640
dc.identifier.issn1750-2659
dc.identifier.urihttps://hdl.handle.net/2027.42/155966
dc.description.abstractBackgroundThe Estudio Vacuna de Influenza Peru (VIP) cohort aims to describe the frequency of influenza virus infection, identify predictors of vaccine acceptance, examine the effects of repeated influenza vaccination on immunogenicity, and evaluate influenza vaccine effectiveness among HCP.MethodsThe VIP cohort prospectively followed HCP in Lima, Peru, during the 2016- 2018 influenza seasons; a fourth year is ongoing. Participants contribute blood samples before and after the influenza season and after influenza vaccination (for vaccinees). Weekly surveillance is conducted to identify acute respiratory or febrile illnesses (ARFI). When an ARFI is identified, participants self- collect nasal swabs that are tested for influenza viruses by real- time reverse transcriptase- polymerase chain reaction. Influenza vaccination status and 5- year vaccination history are ascertained. We analyzed recruitment and enrollment results for 2016- 2018 and surveillance participation for 2016- 2017.ResultsIn the first 3 years of the cohort, VIP successfully contacted 92% of potential participants, enrolled 76% of eligible HCP, and retained >90% of participants across years. About half of participants are medical assistants (54%), and most provide - hands- on- medical care (76%). Sixty- nine percent and 52% of participants completed surveillance for >70% of weeks in years 1 and 2, respectively. Fewer weeks of completed surveillance was associated with older age (- ¥50 years), being a medical assistant, self- rated health of fair or poor, and not receiving the influenza vaccine during the current season (P- values < .05).ConclusionsThe VIP cohort provides an opportunity to address knowledge gaps about influenza virus infection, vaccination uptake, effectiveness and immunogenicity among HCP.
dc.publisherWiley Periodicals, Inc.
dc.subject.otherhealthcare personnel
dc.subject.otherinfluenza
dc.subject.otherinfluenza vaccine
dc.titleProspective cohort study of influenza vaccine effectiveness among healthcare personnel in Lima, Peru: Estudio Vacuna de Influenza Peru, 2016- 2018
dc.typeArticle
dc.rights.robotsIndexNoFollow
dc.subject.hlbsecondlevelMicrobiology and Immunology
dc.subject.hlbtoplevelHealth Sciences
dc.description.peerreviewedPeer Reviewed
dc.description.bitstreamurlhttps://deepblue.lib.umich.edu/bitstream/2027.42/155966/1/irv12737.pdf
dc.description.bitstreamurlhttps://deepblue.lib.umich.edu/bitstream/2027.42/155966/2/irv12737_am.pdf
dc.identifier.doi10.1111/irv.12737
dc.identifier.sourceInfluenza and Other Respiratory Viruses
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dc.owningcollnameInterdisciplinary and Peer-Reviewed


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