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Genetic analysis of post‐epizootic amphibian chytrid strains in Bolivia: Adding a piece to the puzzle

dc.contributor.authorBurrowes, Patricia A.
dc.contributor.authorJames, Timothy Y.
dc.contributor.authorJenkinson, Thomas S.
dc.contributor.authorDe la Riva, Ignacio
dc.date.accessioned2020-10-01T23:30:50Z
dc.date.availableWITHHELD_12_MONTHS
dc.date.available2020-10-01T23:30:50Z
dc.date.issued2020-09
dc.identifier.citationBurrowes, Patricia A.; James, Timothy Y.; Jenkinson, Thomas S.; De la Riva, Ignacio (2020). "Genetic analysis of post‐epizootic amphibian chytrid strains in Bolivia: Adding a piece to the puzzle." Transboundary and Emerging Diseases 67(5): 2163-2171.
dc.identifier.issn1865-1674
dc.identifier.issn1865-1682
dc.identifier.urihttps://hdl.handle.net/2027.42/162756
dc.description.abstractThe evolutionary history and dispersal pattern of Batrachochytrium dendrobatidis (Bd), an emergent fungal pathogen responsible for the decline and extinctions of many species of amphibians worldwide, is still not well understood. In South America, the tropical Andes are known as an important site for amphibian diversification, but also for being a place where hosts are at greater risk of chytridiomycosis. In an attempt to understand the history and the geographic pattern of Bd‐associated amphibian declines in Bolivia, we isolated Bd from hosts at two locations that differ in their chronology of Bd prevalence and host survival outcome, the cloud forests of the Amazonian slopes of the Andes and Lake Titicaca in the altiplano. We genotyped Bd from both locations and sequenced the genome from the cloud forest isolate and then compared them to reference sequences of other Bd strains across the world. We found that the Bolivian chytrid isolates were nearly genotypically identical and that they belong to the global panzootic lineage (Bd‐GPL). The Bolivian Bd strain grouped with other tropical New World strains but was closest to those from the Brazilian Atlantic Forest. Our results extend the presence of Bd‐GPL to the central Andes in South America and report this hypervirulent strain at Lago Titicaca, where Bd has been detected since 1863, without evidence of amphibian declines. These findings suggest a more complex evolutionary history for this pathogen in Bolivia and may point to the existence of an old lineage of Bd that has since been extirpated following the arrival of the panzootic Bd‐GPL or that the timing of Bd‐GPL emergence is earlier than generally acknowledged.
dc.publisherAsociación Herpetológica Española
dc.publisherWiley Periodicals, Inc.
dc.subject.otheramphibian declines
dc.subject.otherchytridiomycosis
dc.subject.otheremergent infectious diseases
dc.subject.otherfungal disease
dc.subject.othergenotyping
dc.subject.otherBatrachochytrium dendrobatidis
dc.titleGenetic analysis of post‐epizootic amphibian chytrid strains in Bolivia: Adding a piece to the puzzle
dc.typeArticle
dc.rights.robotsIndexNoFollow
dc.subject.hlbsecondlevelEpidemiology
dc.subject.hlbtoplevelHealth Sciences
dc.description.peerreviewedPeer Reviewed
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/162756/2/tbed13568_am.pdfen_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/162756/1/tbed13568.pdfen_US
dc.identifier.doi10.1111/tbed.13568
dc.identifier.sourceTransboundary and Emerging Diseases
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dc.owningcollnameInterdisciplinary and Peer-Reviewed


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