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Aerodigestive adverse effects during intravenous pentamidine infusion for Pneumocystis jirovecii pneumonia prophylaxis
dc.contributor.authorSavaşan, Süreyya
dc.contributor.authorGeorge, Amy
dc.contributor.authorSokolowski, Catherine
dc.contributor.authorMcGraw, Bettina Joi
dc.contributor.authorRademacher, Hillary
dc.date.accessioned2020-12-02T14:38:05Z
dc.date.availableWITHHELD_14_MONTHS
dc.date.available2020-12-02T14:38:05Z
dc.date.issued2021-01
dc.identifier.citationSavaşan, Süreyya ; George, Amy; Sokolowski, Catherine; McGraw, Bettina Joi; Rademacher, Hillary (2021). "Aerodigestive adverse effects during intravenous pentamidine infusion for Pneumocystis jirovecii pneumonia prophylaxis." Pediatric Blood & Cancer 68(1): n/a-n/a.
dc.identifier.issn1545-5009
dc.identifier.issn1545-5017
dc.identifier.urihttps://hdl.handle.net/2027.42/163585
dc.description.abstractAerodigestive adverse effects (AD- AE) during intravenous pentamidine (IV- P) infusion for Pneumocystis jiroveci pneumonia prophylaxis are uncommon in retrospective chart review studies. We conducted a survey in patients on IV- P, which included 31 specific questions. Twenty- five patients were included in the analysis; AD- AE were observed in 22 (88%) with recurrence of symptoms in 88% participants with subsequent infusions. Five leading symptoms were congestion (48%), lip tingling (32%), nausea (28%), tongue tingling (24%), vomiting, and throat swelling (17%); multiple symptoms were reported in 72% of the patients. In conclusion, AD- AE of IV- P infusion are common, self- limited, and tend to be recurrent.
dc.publisherWiley Periodicals, Inc.
dc.subject.otheradverse reactions
dc.subject.otherintravenous
dc.subject.otherchildren
dc.subject.otheraero- digestive
dc.subject.otherpentamidine
dc.titleAerodigestive adverse effects during intravenous pentamidine infusion for Pneumocystis jirovecii pneumonia prophylaxis
dc.typeArticle
dc.rights.robotsIndexNoFollow
dc.subject.hlbsecondlevelPediatrics
dc.subject.hlbtoplevelHealth Sciences
dc.description.peerreviewedPeer Reviewed
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/163585/2/pbc28714_am.pdfen_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/163585/1/pbc28714.pdfen_US
dc.identifier.doi10.1002/pbc.28714
dc.identifier.sourcePediatric Blood & Cancer
dc.identifier.citedreferenceLevy ER, Musick L, Zinter MS, et al. Safe and effective prophylaxis with bimonthly intravenous pentamidine in the pediatric hematopoietic stem cell transplant population. Pediatr Infect Dis J. 2016; 35: 135 - 141.
dc.identifier.citedreferenceKruizinga MD, Bresters D, Smiers FJ, Lankester AC, Bredius RGM. The use of intravenous pentamidine for the prophylaxis of Pneumocystis pneumonia in pediatric patients. Pediatr Blood Cancer. 2017; 64. https://doi.org/10.1002/pbc.26453
dc.identifier.citedreferenceQuinn M, Fannin JT, Sciasci J, et al. Pentamidine for prophylaxis against Pneumocystis jirovecii pneumonia in pediatric oncology patients receiving immunosuppressive chemotherapy. Antimicrob Agents Chemother. 2018; 62: e00173 - 18.
dc.identifier.citedreferenceSettipane RA, Kaliner MA. Chapter 14: nonallergic rhinitis. Am J Rhinol Allergy. 2013; 27 ( Suppl 1 ): S48- S51.
dc.identifier.citedreferenceKosirog- Glowacki JL, Bressler LR. Cyclophosphamide- induced facial discomfort. Ann Pharmacother. 1994; 28: 197- 199.
dc.identifier.citedreferenceKalambay J, Ghazanfar H, Martes Pena KA, Munshi RA, Zhang G, Patel JY. Pathogenesis of drug induced non- allergic angioedema: a review of unusual etiologies. Cureus. 2017; 9: e1598.
dc.identifier.citedreferenceLiu Y, Smith CA, Panetta JC, et al Antibodies predict pegaspargase allergic reactions and failure of rechallenge. J Clin Oncol. 2019; 37: 2051 - 2061.
dc.identifier.citedreferenceClark A, Hemmelgarn T, Danziger- Isakov L, Teusink A. Intravenous pentamidine for Pneumocystis carinii/jiroveci pneumonia prophylaxis in pediatric transplant patients. Pediatr Transplant. 2015; 19: 326 - 331.
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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