Alternative option labeling impacts decision- making in noninvasive prenatal screening
dc.contributor.author | Fisher, Camille F. | |
dc.contributor.author | Birkeland, Laura E. | |
dc.contributor.author | Reiser, Catherine A. | |
dc.contributor.author | Zhao, Qianqian | |
dc.contributor.author | Palmer, Christina G. S. | |
dc.contributor.author | Zikmund‐fisher, Brian J. | |
dc.contributor.author | Petty, Elizabeth M. | |
dc.date.accessioned | 2021-01-05T18:46:49Z | |
dc.date.available | WITHHELD_12_MONTHS | |
dc.date.available | 2021-01-05T18:46:49Z | |
dc.date.issued | 2020-12 | |
dc.identifier.citation | Fisher, Camille F.; Birkeland, Laura E.; Reiser, Catherine A.; Zhao, Qianqian; Palmer, Christina G. S.; Zikmund‐fisher, Brian J. ; Petty, Elizabeth M. (2020). "Alternative option labeling impacts decision- making in noninvasive prenatal screening." Journal of Genetic Counseling 29(6): 910-918. | |
dc.identifier.issn | 1059-7700 | |
dc.identifier.issn | 1573-3599 | |
dc.identifier.uri | https://hdl.handle.net/2027.42/163878 | |
dc.description.abstract | Prenatal genetic screening should be an informed, autonomous patient choice. Extrinsic factors which influence patient decision- making threaten the ethical basis of prenatal genetic screening. Prior research in the area of medical decision- making has identified that labeling may have unanticipated effects on patient perceptions and decision- making processes. This Internet- administered study explored the impact of option labeling on the noninvasive prenatal screening (NIPS) selections of US adults. A total of 1,062 participants were recruited through Amazon Mechanical Turk (MTurk) and randomly assigned to one of three possible label sets reflecting provider- derived and industry- derived option labels used in prenatal screening. Multinomial logistic regression analysis showed option labeling had a statistically significant impact on the NIPS selections of study participants (p = .0288). Outcomes of the Satisfaction with Decision Scale (SWD) indicated option labels did not play a role in participant satisfaction with screening selection. The results of this study indicate a need for further evaluation of the impact NIPS option labeling has on patient screening decisions in real- world clinical interactions. Clinical providers and testing laboratories offering NIPS should give careful consideration to the option labels used with prenatal screening so as to minimize influence on patient screening selection and decision- making processes. | |
dc.publisher | Wiley Periodicals, Inc. | |
dc.subject.other | labeling | |
dc.subject.other | decision- making | |
dc.subject.other | genetic counseling | |
dc.subject.other | noninvasive prenatal screening | |
dc.subject.other | options | |
dc.subject.other | prenatal diagnosis | |
dc.subject.other | prenatal whole genome sequencing | |
dc.title | Alternative option labeling impacts decision- making in noninvasive prenatal screening | |
dc.type | Article | |
dc.rights.robots | IndexNoFollow | |
dc.subject.hlbsecondlevel | Human Genetics | |
dc.subject.hlbtoplevel | Health Sciences | |
dc.description.peerreviewed | Peer Reviewed | |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/163878/1/jgc41191_am.pdf | |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/163878/2/jgc41191.pdf | |
dc.identifier.doi | 10.1002/jgc4.1191 | |
dc.identifier.source | Journal of Genetic Counseling | |
dc.identifier.citedreference | Korngiebel, D. M., McMullen, C. K., Amendola, L. M., Berg, J. S., Davis, J. V., Gilmore, M. J., - ¦ Wilfond, B. S. ( 2016 ). Generating a taxonomy for genetic conditions relevant to reproductive planning. American Journal of Medical Genetics Part A, 170 ( 3 ), 565 - 573. https://doi.org/10.1002/ajmg.a.37513 | |
dc.identifier.citedreference | Allen Chan, K. C. A., Jiang, P., Sun, K., Cheng, Y. K. Y., Tong, Y. K., Cheng, S. H., - ¦ Lo, Y. M. D. ( 2016 ). Second generation noninvasive fetal genome analysis reveals de novo mutations, single- base parental inheritance, and preferred DNA ends. Proceedings of the National Academy of Sciences of the United States of America, 113 ( 50 ), E8159 - E8168. https://doi.org/10.1073/pnas.1615800113 | |
dc.identifier.citedreference | Ariosa Diagnostics, Inc. ( 2016 ) Harmony prenatal screening flipbook. Retrieved from https://www.harmonytest.com/content/dam/rochessequence/harmony/worldwide/resources/Prenatal-Screening-Flipbook.pdf | |
dc.identifier.citedreference | Bayefsky, M. J., White, A., Wakim, P., Hull, S. C., Wasserman, D., Chen, S., & Berkman, B. E. ( 2016 ). Views of American OB/GYNs on the ethics of prenatal whole- genome sequencing. Prenatal Diagnosis, 36 ( 13 ), 1250 - 1256. https://doi.org/10.1002/pd.4968 | |
dc.identifier.citedreference | Buhrmester, M., Kwang, T., & Gosling, S. D. ( 2011 ). Amazon- s Mechanical Turk: A new source of inexpensive, yet high quality, data? Perspectives in Psychological Science, 6 ( 1 ), 3 - 5. https://doi.org/10.1177/1745691610393980 | |
dc.identifier.citedreference | Cheung, J. H., Burns, D. K., Sinclair, R. R., & Sliter, M. ( 2016 ). Amazon Mechanical Turk in organizational psychology: An evaluation and practical recommendations. Journal of Business and Psychology, 32 ( 4 ), 347 - 361. https://doi.org/10.1007/s10869-016-9458-5 | |
dc.identifier.citedreference | Dolan, J. G., Cherkasky, O. A., Chin, N., & Veazie, P. J. ( 2015 ). Decision aids: The effect of labeling options on patient choices and decision- making. Medical Decision Making, 35 ( 8 ), 979 - 986. https://doi.org/10.1177/0272989X15598532 | |
dc.identifier.citedreference | Drury, S., Hill, M., & Chitty, L. S. ( 2016 ). Cell- free fetal DNA testing for prenatal diagnosis. Advances in Clinical Chemistry, 76, 1 - 35. https://doi.org/10.1016/bs.acc.2016.05.004 | |
dc.identifier.citedreference | Farrell, R. M., Hawkins, A., Barragan, D., Hudgins, L., & Taylor, J. ( 2015 ). Knowledge, understanding, and uptake of noninvasive prenatal testing among Latina women. Prenatal Diagnosis, 35 ( 8 ), 748 - 753. https://doi.org/10.1002/pd.4599 | |
dc.identifier.citedreference | Floyd, E., Allyse, M. A., & Michie, M. ( 2016 ). Spanish- and English- speaking pregnant women- s views of cfDNA and other prenatal screening: Practical and ethical reflections. Journal of Genetic Counseling, 25, 965 - 977. https://doi.org/10.1007/s10897-015-9928-3 | |
dc.identifier.citedreference | Hibbard, J. H., & Peters, E. ( 2003 ). Supporting informed consumer health care decisions: Data presentation approaches that facilitate the use of information in choice. Annual Review of Public Health, 24, 413 - 433. https://doi.org/10.1146/annurev.publhealth.24.100901.141005 | |
dc.identifier.citedreference | Ho, G. C., Shih, M., & Walters, D. J. ( 2012 ). Labels and leaders: The influence of framing on leadership emergence. The Leadership Quarterly, 23, 943 - 952. https://doi.org/10.1016/j.leaqua.2012.06.003 | |
dc.identifier.citedreference | Holmes- Rovner, M., Kroll, J., Schmitt, N., Rovner, D. R., Breer, M. L., Rothert, M. L., - ¦ Talarczyk, G. ( 1996 ). Patient satisfaction with health care decisions: The satisfaction with decision scale. Medical Decision Making, 16 ( 1 ), 58 - 64. https://doi.org/10.1177/0272989X9601600114 | |
dc.identifier.citedreference | Liu, L., Li, K., Fu, X., Chung, C., & Zhang, K. ( 2016 ). A forward look at noninvasive prenatal testing. Trends in Molecular Medicine, 22 ( 11 ), 958 - 968. https://doi.org/10.1016/j.molmed.2016.09.008 | |
dc.identifier.citedreference | Lubitz, R. J., Komaromy, M., Crawford, B., Beattie, M., Lee, R., Luce, J., & Ziegler, J. ( 2007 ). Development and pilot evaluation of novel genetic educational materials designed for an underserved patient population. Genetic Testing, 11 ( 3 ), 276 - 290. https://doi.org/10.1089/gte.2007.0012 | |
dc.identifier.citedreference | Morris, M. W., Carranza, E., & Fox, C. R. ( 2008 ). Mistaken identity: Activating conservative political identities induces - conservative- financial decisions. Psychological Science, 19 ( 11 ), 1154 - 1160. https://doi.org/10.1111/j.1467-9280.2008.02217.x | |
dc.identifier.citedreference | Peer, E., Vosgerau, J., & Acquisiti, A. ( 2014 ). Reputation as sufficient condition for data quality on Amazon Mechanical Turk. Behavior Research Methods, 46, 1023 - 1031. https://doi.org/10.3758/s13428-013-0434-y | |
dc.identifier.citedreference | Progenity, Inc. ( 2017 ). Preparent global panel performance. Retrieved from https://progenity.com/sites/default/files/resources/preparent_global_carrier_screen_risk_table_2016_10_20_102016version_final.pdf#view=Fit | |
dc.identifier.citedreference | Sequenom Laboratories. ( 2017 ). MaterniT21 PLUS core patient brochure. Retrieved from https://www.sequenom.com/uploads/collateral/MaterniT-21-PLUS-core-patient-brochure_Rep-1036-v1-0117.pdf | |
dc.identifier.citedreference | Zikmund- Fisher, B. J., Fagerlin, A., Keeton, K., & Ubel, P. A. ( 2007 ). Does labeling prenatal screening test results as negative or positive affect women- s responses? American Journal of Obstetrics and Gynecology, 197 ( 5 ), 528.e1 - 528.e6. | |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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