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Using race to estimate glomerular filtration and its impact in kidney transplantation

dc.contributor.authorKuppachi, Sarat
dc.contributor.authorNorman, Silas P.
dc.contributor.authorLentine, Krista L.
dc.contributor.authorAxelrod, David A.
dc.date.accessioned2021-02-04T21:50:22Z
dc.date.available2022-02-04 16:50:20en
dc.date.available2021-02-04T21:50:22Z
dc.date.issued2021-01
dc.identifier.citationKuppachi, Sarat; Norman, Silas P.; Lentine, Krista L.; Axelrod, David A. (2021). "Using race to estimate glomerular filtration and its impact in kidney transplantation." Clinical Transplantation (1): n/a-n/a.
dc.identifier.issn0902-0063
dc.identifier.issn1399-0012
dc.identifier.urihttps://hdl.handle.net/2027.42/166197
dc.description.abstractSince direct measurement of glomerular filtration rate (GFR) is time‐consuming and more expensive, estimated GFR (eGFR) based on measured laboratory values is widely used to determine kidney function. Commonly used formulae to calculate eGFR are dependent on variables, which include filtration markers like serum creatinine and patient characteristics including race. Medical algorithms which utilize race are increasingly being scrutinized, as race is recognized to be a social construct rather than a biologic one. eGFR calculations have important implications for kidney transplantation, both in the listing of candidates as well as in the evaluation of potential kidney donors. This review considers the specific implications of race‐based eGFR calculations on recipient evaluation and on decisions related to living kidney donation. We suggest a potential policy solution to ensure that racial and ethnic minority patients are not disadvantaged by eGFR as a result of current calculation methods.
dc.publisherWiley Periodicals, Inc.
dc.subject.otherdisparities
dc.subject.otherOrgan Procurement and Transplantation Network
dc.subject.otherrace
dc.subject.otherliving
dc.subject.otherglomerular filtration rate
dc.subject.otherethnicity
dc.subject.otherdonors and donation
dc.titleUsing race to estimate glomerular filtration and its impact in kidney transplantation
dc.typeArticle
dc.rights.robotsIndexNoFollow
dc.subject.hlbsecondlevelMedicine (General)
dc.subject.hlbtoplevelHealth Sciences
dc.description.peerreviewedPeer Reviewed
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/166197/1/ctr14136.pdf
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/166197/2/ctr14136_am.pdf
dc.identifier.doi10.1111/ctr.14136
dc.identifier.doihttps://dx.doi.org/10.7302/120
dc.identifier.sourceClinical Transplantation
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dc.working.doi10.7302/120en
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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