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Startle to neutral, not negative stimuli: A neurophysiological correlate of behavioral inhibition in young children
dc.contributor.authorPremo, Julie E.
dc.contributor.authorMannella, Kristin A.
dc.contributor.authorDuval, Elizabeth R.
dc.contributor.authorLiu, Yanni
dc.contributor.authorMorrison, Claire L.
dc.contributor.authorMoser, Jason S.
dc.contributor.authorMuzik, Maria
dc.contributor.authorRosenblum, Katherine L.
dc.contributor.authorFitzgerald, Kate D.
dc.date.accessioned2021-09-08T14:36:56Z
dc.date.available2022-08-08 10:36:55en
dc.date.available2021-09-08T14:36:56Z
dc.date.issued2021-07
dc.identifier.citationPremo, Julie E.; Mannella, Kristin A.; Duval, Elizabeth R.; Liu, Yanni; Morrison, Claire L.; Moser, Jason S.; Muzik, Maria; Rosenblum, Katherine L.; Fitzgerald, Kate D. (2021). "Startle to neutral, not negative stimuli: A neurophysiological correlate of behavioral inhibition in young children." Developmental Psychobiology 63(5): 1322-1329.
dc.identifier.issn0012-1630
dc.identifier.issn1098-2302
dc.identifier.urihttps://hdl.handle.net/2027.42/169324
dc.description.abstractA putative biomarker of anxiety risk, the startle response is typically enhanced by negative compared to neutral emotion modulation in adults, but remains understudied in children. To determine the extent to which neutral, negative, and positively valenced emotional conditions modulate startle response in early life, a child‐friendly film paradigm was used to vary emotion across these conditions during startle induction in sixty‐four 4‐ to 7‐year‐old children. Association of emotion‐modulated startle with parent‐reported anxiety symptom severity and child behavioral inhibition, a risk factor for anxiety problems, were assessed. Analyses revealed no difference in startle magnitude during negative compared to neutral film clips. By contrast, startle during both negative and neutral conditions was greater than startle during the positive condition. Larger startle magnitude during the neutral condition associated with higher levels of child behavioral inhibition (BI). These results are consistent with possible immaturity of startle response in young children, and suggest that startle amplitude in more emotionally ambiguous, neutral conditions could serve as an early biomarker for anxiety risk.
dc.publisherWiley Periodicals, Inc.
dc.publisherAseba
dc.subject.otherstartle response
dc.subject.otheranxiety
dc.subject.otherbehavioral inhibition
dc.subject.otherearly childhood
dc.titleStartle to neutral, not negative stimuli: A neurophysiological correlate of behavioral inhibition in young children
dc.typeArticle
dc.rights.robotsIndexNoFollow
dc.subject.hlbsecondlevelEcology and Evolutionary Biology
dc.subject.hlbtoplevelScience
dc.description.peerreviewedPeer Reviewed
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/169324/1/dev22120_am.pdf
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/169324/2/dev22120.pdf
dc.identifier.doi10.1002/dev.22120
dc.identifier.sourceDevelopmental Psychobiology
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dc.working.doiNOen
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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