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A Highly Ordered, Nanostructured Fluorinated CaP‐Coated Melt Electrowritten Scaffold for Periodontal Tissue Regeneration

dc.contributor.authorDaghrery, Arwa
dc.contributor.authorFerreira, Jessica A.
dc.contributor.authorDe Souza Araújo, Isaac J.
dc.contributor.authorClarkson, Brian H.
dc.contributor.authorEckert, George J.
dc.contributor.authorBhaduri, Sarit B.
dc.contributor.authorMalda, Jos
dc.contributor.authorBottino, Marco C.
dc.date.accessioned2021-12-02T02:29:15Z
dc.date.available2022-12-01 21:29:13en
dc.date.available2021-12-02T02:29:15Z
dc.date.issued2021-11
dc.identifier.citationDaghrery, Arwa; Ferreira, Jessica A.; De Souza Araújo, Isaac J. ; Clarkson, Brian H.; Eckert, George J.; Bhaduri, Sarit B.; Malda, Jos; Bottino, Marco C. (2021). "A Highly Ordered, Nanostructured Fluorinated CaP‐Coated Melt Electrowritten Scaffold for Periodontal Tissue Regeneration." Advanced Healthcare Materials 10(21): n/a-n/a.
dc.identifier.issn2192-2640
dc.identifier.issn2192-2659
dc.identifier.urihttps://hdl.handle.net/2027.42/170974
dc.description.abstractPeriodontitis is a chronic inflammatory, bacteria‐triggered disorder affecting nearly half of American adults. Although some level of tissue regeneration is realized, its low success in complex cases demands superior strategies to amplify regenerative capacity. Herein, highly ordered scaffolds are engineered via Melt ElectroWriting (MEW), and the effects of strand spacing, as well as the presence of a nanostructured fluorinated calcium phosphate (F/CaP) coating on the adhesion/proliferation, and osteogenic differentiation of human‐derived periodontal ligament stem cells, are investigated. Upon initial cell‐scaffold interaction screening aimed at defining the most suitable design, MEW poly(ε‐caprolactone) scaffolds with 500 µm strand spacing are chosen. Following an alkali treatment, scaffolds are immersed in a pre‐established solution to allow for coating formation. The presence of a nanostructured F/CaP coating leads to a marked upregulation of osteogenic genes and attenuated bacterial growth. In vivo findings confirm that the F/CaP‐coated scaffolds are biocompatible and lead to periodontal regeneration when implanted in a rat mandibular periodontal fenestration defect model. In aggregate, it is considered that this work can contribute to the development of personalized scaffolds capable of enabling tissue‐specific differentiation of progenitor cells, and thus guide simultaneous and coordinated regeneration of soft and hard periodontal tissues, while providing antimicrobial protection.This work can contribute to the development of personalized biocompatible and biodegradable scaffolds capable of enabling tissue‐specific differentiation of resident progenitor cells, and thus guide simultaneous and coordinated regeneration of soft and hard periodontal tissues, while providing antimicrobial protection.
dc.publisherWiley Periodicals, Inc.
dc.publisherHumana Press
dc.subject.otherbones
dc.subject.other3D printing
dc.subject.otherscaffolds
dc.subject.othermelt electrowriting
dc.subject.otherperiodontal regeneration
dc.subject.otherperiodontitis
dc.titleA Highly Ordered, Nanostructured Fluorinated CaP‐Coated Melt Electrowritten Scaffold for Periodontal Tissue Regeneration
dc.typeArticle
dc.rights.robotsIndexNoFollow
dc.subject.hlbsecondlevelMaterials Science and Engineering
dc.subject.hlbtoplevelEngineering
dc.description.peerreviewedPeer Reviewed
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/170974/1/adhm202101152.pdf
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/170974/2/adhm202101152_am.pdf
dc.identifier.doi10.1002/adhm.202101152
dc.identifier.sourceAdvanced Healthcare Materials
dc.identifier.citedreferenceD. Perera‐Costa, J. M. Bruque, M. L. González‐Martín, A. C. Gómez‐García, V. Vadillo‐Rodríguez, Langmuir 2014, 30, 4633.
dc.identifier.citedreferenceN. Eliaz, N. Metoki‐Shlubsky, Materials 2017, 10, 334.
dc.identifier.citedreferenceF. Tamimi, Z. Sheikh, J. Barralet, Acta Biomater. 2012, 8, 474.
dc.identifier.citedreferenceN. J. Hogrebe, J. W. Reinhardt, K. J. Gooch, J. Biomed. Mater. Res., Part A 2017, 105, 640.
dc.identifier.citedreferenceA. Daghrery, Z. Aytac, N. Dubey, L. Mei, A. Schwendeman, M. C. Bottino, Colloids Surf., B 2020, 191, 111011.
dc.identifier.citedreferenceC. Vaquette, S. Ivanovski, S. M. Hamlet, D. W. Hutmacher, Biomaterials 2013, 34, 5538.
dc.identifier.citedreferenceX. Ge, Y. Leng, C. Bao, S. L. Xu, R. Wang, F. Ren, J. Biomed. Mater. Res., Part A 2010, 95A, 588.
dc.identifier.citedreferenceM. Kargar, Y.‐R., K. Chang, H. Hoseinabad, A. Pruden, W. A. Ducker, ACS Biomater. Sci. Eng. 2016, 2, 1039.
dc.identifier.citedreferenceS. M. Kelleher, O. Habimana, J. Lawler, B. O’ Reilly, S. Daniels, E. Casey, A. Cowley, ACS Appl. Mater. Interfaces 2016, 8, 14966.
dc.identifier.citedreferenceK. Manabe, S. Nishizawa, S. Shiratori, ACS Appl. Mater. Interfaces 2013, 5, 11900.
dc.identifier.citedreferenceM. Abrigo, P. Kingshott, S. L. McArthur, ACS Appl. Mater. Interfaces 2015, 7, 7644.
dc.identifier.citedreferenceL. D. Renner, D. B. Weibel, MRS Bull. 2011, 36, 347.
dc.identifier.citedreferenceA. G. Gristina, P. Naylor, Q. Myrvik, Med. Prog. Technol. 1988, 14, 205.
dc.identifier.citedreferenceY. L. Jeyachandran, S. K. Narayandass, D. Mangalaraj, C. Y. Bao, W. Li, Y. M. Liao, C. L. Zhang, L. Y. Xiao, W. C. Chen, Surf. Coat. Technol. 2006, 201, 3462.
dc.identifier.citedreferenceA. Aguirre, A. González, M. Navarro, O. Castaño, J. A. Planell, E. Engel, Eur. Cells Mater. 2012, 24, 90.
dc.identifier.citedreferenceM. Barbeck, T. Serra, P. Booms, S. Stojanovic, S. Najman, E. Engel, R. Sader, C. J. Kirkpatrick, M. Navarro, S. Ghanaati, Bioact. Mater. 2017, 2, 208.
dc.identifier.citedreferenceH. Dan, C. Vaquette, A. G. Fisher, S. M. Hamlet, Y. Xiao, D. W. Hutmacher, S. Ivanovski, Biomaterials 2014, 35, 113.
dc.identifier.citedreferenceG. Pellegrini, Y. J. Seol, R. Gruber, W. Giannobile, J. Dent. Res. 2009, 88, 1065.
dc.identifier.citedreferenceM. Padial‐Molina, J. T. Marchesan, A. D. Taut, Q. Jin, W. V. Giannobile, H. F. Rios, in Odontogenesis: Methods and Protocols, (Ed: C. Kioussi ), Humana Press, Totowa, NJ, 2012, pp. 135 – 148.
dc.identifier.citedreferenceN. Abbasi, R. S. B. Lee, S. Ivanovski, R. M. Love, S. Hamlet, Biomater. Res. 2020, 24, 17.
dc.identifier.citedreferenceS. Ivanovski, C. Vaquette, S. Gronthos, D. W. Hutmacher, P. M. Bartold, J. Dent. Res. 2014, 93, 1212.
dc.identifier.citedreferenceG. Criscenti, A. Longoni, A. D. Luca, C. D. Maria, C. A. van Blitterswijk, G. Vozzi, L. Moroni, Biofabrication 2016, 8, 015009.
dc.identifier.citedreferenceS.‐S. D. Carter, P. F. Costa, C. Vaquette, S. Ivanovski, D. W. Hutmacher, J. Malda, Ann. Biomed. Eng. 2017, 45, 12.
dc.identifier.citedreferenceJ. Visser, F. P. W. Melchels, J. E. Jeon, E. M. van Bussel, L. S. Kimpton, H. M. Byrne, W. J. A. Dhert, P. D. Dalton, D. W. Hutmacher, J. Malda, Nat. Commun. 2015, 6, 6933.
dc.identifier.citedreferenceT. Guo, Y. Li, G. Cao, Z. Zhang, S. Chang, A. Czajka‐Jakubowska, J. E. Nör, B. H. Clarkson, J. Liu, J. Dent. Res. 2014, 93, 1290.
dc.identifier.citedreferenceC. Grove, D. A. Jerram, Comput. Geosci. 2011, 37, 1850.
dc.identifier.citedreferenceH. Liu, Y. Du, J.‐P. St‐Pierre, M. S. Bergholt, H. Autefage, J. Wang, M. Cai, G. Yang, M. M. Stevens, S. Zhang, Sci. Adv. 2020, 6, eaay7608.
dc.identifier.citedreferenceT. Kokubo, H. Takadama, Biomaterials 2006, 27, 2907.
dc.identifier.citedreferenceL. Ji, W. Wang, D. Jin, S. Zhou, X. Song, Mater. Sci. Eng., C 2015, 46, 1.
dc.identifier.citedreferenceS. Yeasmin, J. Ceccarelli, M. Vigen, B. Carrion, A. J. Putnam, S. A. Tarle, D. Kaigler, Tissue Eng., Part A 2014, 20, 1188.
dc.identifier.citedreferenceA. Oyane, M. Uchida, C. Choong, J. Triffitt, J. Jones, A. Ito, Biomaterials 2005, 26, 2407.
dc.identifier.citedreferenceA. A. Zadpoor, Mater. Sci. Eng., C 2014, 35, 134.
dc.identifier.citedreferenceF. Verisqa, S. Triaminingsih, J. E. M. Corputty, J. Phys.: Conf. Ser. 2017, 884, 012035.
dc.identifier.citedreferenceC. J. S. Ibsen, D. Chernyshov, H. Birkedal, Chem. – Eur. J. 2016, 22, 12347.
dc.identifier.citedreferenceE. A. Münchow, M. T. P. Albuquerque, B. Zero, K. Kamocki, E. Piva, R. L. Gregory, M. C. Bottino, Dent. Mater. 2015, 31, 1038.
dc.identifier.citedreferenceE. A. Münchow, D. Pankajakshan, M. T. P. Albuquerque, K. Kamocki, E. Piva, R. L. Gregory, M. C. Bottino, Clin. Oral Investig. 2016, 20, 1921.
dc.identifier.citedreferenceA. Bužarovska, J. Mater. Sci. 2017, 52, 12067.
dc.identifier.citedreferenceN. Montazeri, R. Jahandideh, E. Biazar, Int. J. Nanomed. 2011, 6, 197.
dc.identifier.citedreferenceB. T. Bennett, J. P. Beck, K. Papangkorn, J. S. Colombo, K. N. Bachus, J. Agarwal, J. F. Shieh, S. Jeyapalina, Mater. Sci. Eng., C 2019, 100, 665.
dc.identifier.citedreferenceM. U. Hashmi, S. A. Shah, Prog. Nat. Sci.: Mater. Int. 2014, 24, 354.
dc.identifier.citedreferenceP. I. Eke, B. A. Dye, L. Wei, G. D. Slade, G. O. Thornton‐Evans, W. S. Borgnakke, G. W. Taylor, R. C. Page, J. D. Beck, R. J. Genco, J. Periodontol. 2015, 86, 611.
dc.identifier.citedreferenceM. C. Bottino, V. Thomas, G. Schmidt, Y. K. Vohra, T.‐M. G. Chu, M. J. Kowolik, G. M. Janowski, Dent. Mater. 2012, 28, 703.
dc.identifier.citedreferenceM. M. Hasani‐Sadrabadi, P. Sarrion, N. Nakatsuka, T. D. Young, N. Taghdiri, S. Ansari, T. Aghaloo, S. Li, A. Khademhosseini, P. S. Weiss, A. Moshaverinia, ACS Nano 2019, 13, 3830.
dc.identifier.citedreferenceJ. Tan, M. Zhang, Z. Hai, C. Wu, J. Lin, W. Kuang, H. Tang, Y. Huang, X. Chen, G. Liang, ACS Nano 2019, 13, 5616.
dc.identifier.citedreferenceZ. Aytac, N. Dubey, A. Daghrery, J. A. Ferreira, I. J. Araújo, S. de, M. Castilho, J. Malda, M. C. Bottino, Int. Mater. Rev. 2021, https://doi.org/10.1080/09506608.2021.1946236.
dc.identifier.citedreferenceM. C. Bottino, V. Thomas, G. M. Janowski, Acta Biomater. 2011, 7, 216.
dc.identifier.citedreferenceB. A. Blakeney, A. Tambralli, J. M. Anderson, A. Andukuri, D.‐J. Lim, D. R. Dean, H.‐W. Jun, Biomaterials 2011, 32, 1583.
dc.identifier.citedreferenceG. Rasperini, S. P. Pilipchuk, C. L. Flanagan, C. H. Park, G. Pagni, S. J. Hollister, W. V. Giannobile, J. Dent. Res. 2015, 94, 153S.
dc.identifier.citedreferenceN. Abbasi, S. Hamlet, V. T. Dau, N.‐T. Nguyen, J. Sci.: Adv. Mater. Devices 2020, 5, 30.
dc.identifier.citedreferenceJ. Liu, T. Jin, S. Chang, A. Czajka‐Jakubowska, Z. Zhang, J. E. Nör, B. H. Clarkson, Tissue Eng., Part A 2010, 16, 2977.
dc.identifier.citedreferenceP. Sikder, Y. Ren, S. B. Bhaduri, J. Mater. Res. 2019, 34, 3766.
dc.identifier.citedreferenceU. Little, F. Buchanan, E. Harkin‐Jones, B. Graham, B. Fox, A. Boyd, B. Meenan, G. Dickson, Acta Biomater. 2009, 5, 2025.
dc.identifier.citedreferenceN. Abbasi, A. Abdal‐hay, S. Hamlet, E. Graham, S. Ivanovski, ACS Biomater. Sci. Eng. 2019, 5, 3448.
dc.identifier.citedreferenceN. Dubey, J. A. Ferreira, A. Daghrery, Z. Aytac, J. Malda, S. B. Bhaduri, M. C. Bottino, Acta Biomater. 2020, 113, 164.
dc.identifier.citedreferenceN. Abbasi, S. Ivanovski, K. Gulati, R. M. Love, S. Hamlet, Biomater. Res. 2020, 24, 2.
dc.identifier.citedreferenceC. Xie, Q. Gao, P. Wang, L. Shao, H. Yuan, J. Fu, W. Chen, Y. He, Mater. Des. 2019, 181, 108092.
dc.identifier.citedreferenceA. Fuchs, A. Youssef, A. Seher, G. Hochleitner, P. D. Dalton, S. Hartmann, R. C. Brands, U. D. A. Müller‐Richter, C. Linz, BMC Oral Health 2019, 19, 28.
dc.identifier.citedreferenceA. Fuchs, A. Youssef, A. Seher, S. Hartmann, R. C. Brands, U. D. A. Müller‐Richter, A. C. Kübler, C. Linz, J. Cranio‐Maxillofac. Surg. 2019, 47, 695.
dc.identifier.citedreferenceH. Shi, W. Zong, X. Xu, J. Chen, Am. J. Transl. Res. 2018, 10, 4030.
dc.identifier.citedreferenceE. Babaie, S. B. Bhaduri, ACS Biomater. Sci. Eng. 2018, 4, 1.
dc.identifier.citedreferenceJ. M. Fernandez, M. S. Molinuevo, M. S. Cortizo, A. M. Cortizo, J. Tissue Eng. Regener. Med. 2011, 5, e126.
dc.identifier.citedreferenceH. L. Jang, G. B. Zheng, J. Park, H. D. Kim, H.‐R. Baek, H. K. Lee, K. Lee, H. N. Han, C.‐K. Lee, N. S. Hwang, J. H. Lee, K. T. Nam, Adv. Healthcare Mater. 2016, 5, 128.
dc.identifier.citedreferenceA. Ogose, T. Hotta, H. Kawashima, N. Kondo, W. Gu, T. Kamura, N. Endo, J. Biomed. Mater. Res., Part B 2005, 72B, 94.
dc.identifier.citedreferenceJ.‐W. Kim, K.‐H. Shin, Y.‐H. Koh, M. J. Hah, J. Moon, H.‐E. Kim, Materials 2017, 10, 1123.
dc.identifier.citedreferenceG. Chouzouri, M. Xanthos, Acta Biomater. 2007, 3, 745.
dc.working.doiNOen
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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