Near‐Infrared Multilayer MoS2 Photoconductivity‐Enabled Ultrasensitive Homogeneous Plasmonic Colorimetric Biosensing
dc.contributor.author | Park, Younggeun | |
dc.contributor.author | Ryu, Byunghoon | |
dc.contributor.author | Ki, Seung Jun | |
dc.contributor.author | Liang, Xiaogan | |
dc.contributor.author | Kurabayashi, Katsuo | |
dc.date.accessioned | 2022-01-06T15:50:45Z | |
dc.date.available | 2023-01-06 10:50:43 | en |
dc.date.available | 2022-01-06T15:50:45Z | |
dc.date.issued | 2021-12 | |
dc.identifier.citation | Park, Younggeun; Ryu, Byunghoon; Ki, Seung Jun; Liang, Xiaogan; Kurabayashi, Katsuo (2021). "Near‐Infrared Multilayer MoS2 Photoconductivity‐Enabled Ultrasensitive Homogeneous Plasmonic Colorimetric Biosensing." Advanced Materials Interfaces 8(24): n/a-n/a. | |
dc.identifier.issn | 2196-7350 | |
dc.identifier.issn | 2196-7350 | |
dc.identifier.uri | https://hdl.handle.net/2027.42/171210 | |
dc.description.abstract | The ability to detect low‐abundance proteins in human body fluids plays a critical role in proteomic research to achieve a comprehensive understanding of protein functions and early‐stage disease diagnosis to reduce mortality rates. Ultrasensitive (sub‐fM), rapid, simple “mix‐and‐read” plasmonic colorimetric biosensing of large‐size (≈180 kDa) proteins in biofluids using an ultralow‐noise multilayer molybdenum disulfide (MoS2) photoconducting channel is reported here. With its out‐of‐plane structure optimized to minimize carrier scattering, the multilayer MoS2 channel operated under near‐infrared illumination enables the detection of a subtle plasmonic extinction shift caused by antigen‐induced nanoprobe aggregation. The demonstrated biosensing strategy allows quantifying carcinoembryonic antigen in unprocessed whole blood with a dynamic range of 106, a sample‐to‐answer time of 10 min, and a limit of detection of 0.1–3 pg mL−1, which is ≈100‐fold more sensitive than the clinical‐standard enzyme‐linked immunosorbent assays. The biosensing methodology can be broadly used to realize timely personalized diagnostics and physiological monitoring of diseases in point‐of‐care settings.A plasmonic colorimetric biosensing platform for rapid and ultrasensitive detection of cancer biomarkers in biofluids is developed using an ultralow‐noise multilayer molybdenum disulfide (MoS2) photoconducting channel. Near‐infrared operation of the multilayer MoS2 channel coupled with a nanoparticle aggregation‐based assay enables user‐friendly homogeneous on‐chip immunosensing that is poised for point‐of‐care testing. | |
dc.publisher | Wiley Periodicals, Inc. | |
dc.subject.other | localized surface plasmon resonance | |
dc.subject.other | point‐of‐care immunoassay | |
dc.subject.other | plasmonic colorimetric biosensors | |
dc.subject.other | carcinoembryonic antigen detection | |
dc.subject.other | multilayer MoS2 | |
dc.title | Near‐Infrared Multilayer MoS2 Photoconductivity‐Enabled Ultrasensitive Homogeneous Plasmonic Colorimetric Biosensing | |
dc.type | Article | |
dc.rights.robots | IndexNoFollow | |
dc.subject.hlbsecondlevel | Materials Science and Engineering | |
dc.subject.hlbtoplevel | Engineering | |
dc.description.peerreviewed | Peer Reviewed | |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/171210/1/admi202101291_am.pdf | |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/171210/2/admi202101291.pdf | |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/171210/3/admi202101291-sup-0001-SuppMat.pdf | |
dc.identifier.doi | 10.1002/admi.202101291 | |
dc.identifier.source | Advanced Materials Interfaces | |
dc.identifier.citedreference | K. F. Mak, C. Lee, J. Hone, J. Shan, T. F. Heinz, Phys. Rev. Lett. 2010, 105, 136805. | |
dc.identifier.citedreference | P. Moitra, M. Alafeef, K. Dighe, M. B. Frieman, D. Pan, ACS Nano 2020, 14, 7617. | |
dc.identifier.citedreference | R. de la Rica, M. M. Stevens, Nat. Nanotechnol. 2012, 7, 821. | |
dc.identifier.citedreference | Y. Park, B. Ryu, Q. Deng, B. Pan, Y. Song, Y. Tian, H. B. Alam, Y. Li, X. Liang, K. Kurabayashi, Small 2020, 16, 1905611. | |
dc.identifier.citedreference | Y. Park, B. Ryu, S. J. Ki, B. McCracken, A. Pennington, K. R. Ward, X. Liang, K. Kurabayashi, ACS Nano 2021, 15, 7722. | |
dc.identifier.citedreference | Y. Park, B. Ryu, B.‐R. Oh, Y. Song, X. Liang, K. Kurabayashi, ACS Nano 2017, 11, 5697. | |
dc.identifier.citedreference | L. Britnell, R. M. Ribeiro, A. Eckmann, R. Jalil, B. D. Belle, A. Mishchenko, Y.‐J. Kim, R. V. Gorbachev, T. Georgiou, S. V. Morozov, A. N. Grigorenko, A. K. Geim, C. Casiraghi, A. H. C. Neto, K. S. Novoselov, Science 2013, 340, 1311. | |
dc.identifier.citedreference | S. Wi, M. Chen, H. Nam, A. C. Liu, E. Meyhofer, X. Liang, Appl. Phys. Lett. 2014, 104, 232103. | |
dc.identifier.citedreference | A. Splendiani, L. Sun, Y. Zhang, T. Li, J. Kim, C.‐Y. Chim, G. Galli, F. Wang, Nano Lett. 2010, 10, 1271. | |
dc.identifier.citedreference | S. Lebègue, O. Eriksson, Phys. Rev. B 2009, 79, 115409. | |
dc.identifier.citedreference | K. F. Mak, J. Shan, Nat. Photonics 2016, 10, 216. | |
dc.identifier.citedreference | J. D. Cohen, L. Li, Y. Wang, C. Thoburn, B. Afsari, L. Danilova, C. Douville, A. A. Javed, F. Wong, A. Mattox, R. H. Hruban, C. L. Wolfgang, M. G. Goggins, M. Dal Molin, T.‐L. Wang, R. Roden, A. P. Klein, J. Ptak, L. Dobbyn, J. Schaefer, N. Silliman, M. Popoli, J. T. Vogelstein, J. D. Browne, R. E. Schoen, R. E. Brand, J. Tie, P. Gibbs, H.‐L. Wong, A. S. Mansfield, J. Jen, S. M. Hanash, M. Falconi, P. J. Allen, S. Zhou, C. Bettegowda, L. A. Diaz, C. Tomasetti, K. W. Kinzler, B. Vogelstein, A. M. Lennon, N. Papadopoulos, Science 2018, 359, 926. | |
dc.identifier.citedreference | D. Aili, M. M. Stevens, Chem. Soc. Rev. 2010, 39, 3358. | |
dc.identifier.citedreference | P. L. Wei, L. T. Lee, L. M. Tseng, K. W. Huang, Sci. Rep. 2018, 8, 10002. | |
dc.identifier.citedreference | X. Yuan, T. Bian, J. Liu, H. Ke, J. Feng, Q. Zhang, L. Qian, X. Li, Y. Liu, J. Zhang, Oncotarget 2017, 8, 59324. | |
dc.identifier.citedreference | G. M. Saied, W. H. El‐Metenawy, M. S. Elwan, N. R. Dessouki, World J. Surg. Oncol. 2007, 5, 4. | |
dc.identifier.citedreference | J. Zheng, L. Sun, W. Yuan, J. Xu, X. Yu, F. Wang, L. Sun, Y. Zeng, Journal of oral pathology & medicine: official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2018, 47, 830. | |
dc.identifier.citedreference | M. Retout, H. Valkenier, E. Triffaux, T. Doneux, K. Bartik, G. Bruylants, ACS Sens. 2016, 1, 929. | |
dc.identifier.citedreference | D. Aili, R. Selegard, L. Baltzer, K. Enander, B. Liedberg, Small 2009, 5, 2445. | |
dc.identifier.citedreference | C. C. Huang, Y. F. Huang, Z. H. Cao, W. H. Tan, H. T. Chang, Anal. Chem. 2005, 77, 5735. | |
dc.identifier.citedreference | H. Wei, B. L. Li, J. Li, E. K. Wang, S. J. Dong, Chem. Commun. 2007, 3735. | |
dc.identifier.citedreference | H. Q. Liu, P. F. Rong, H. W. Jia, J. Yang, B. Dong, Q. Dong, C. J. Yang, P. Z. Hu, W. Wang, H. T. Liu, D. B. Liu, Theranostics 2016, 6, 54. | |
dc.identifier.citedreference | M. Grzelczak, J. Pérez‐Juste, P. Mulvaney, L. M. Liz‐Marzán, Chem. Soc. Rev. 2008, 37, 1783. | |
dc.identifier.citedreference | P. Chen, M. T. Chung, W. McHugh, R. Nidetz, Y. Li, J. Fu, T. T. Cornell, T. P. Shanley, K. Kurabayashi, ACS Nano 2015, 9, 4173. | |
dc.identifier.citedreference | B.‐R. Oh, N.‐T. Huang, W. Chen, J. H. Seo, P. Chen, T. T. Cornell, T. P. Shanley, J. Fu, K. Kurabayashi, ACS Nano 2014, 8, 2667. | |
dc.identifier.citedreference | A. K. Mattox, C. Bettegowda, S. Zhou, N. Papadopoulos, K. W. Kinzler, B. Vogelstein, Sci. Transl. Med. 2019, 11, eaay1984. | |
dc.identifier.citedreference | S. Hammarström, Semin. Cancer Biol. 1999, 9, 67. | |
dc.identifier.citedreference | L. Hernández, A. Espasa, C. Fernández, A. Candela, C. MartÍn, S. Romero, Lung Cancer 2002, 36, 83. | |
dc.identifier.citedreference | F. Naghibalhossaini, P. Ebadi, Cancer Lett. 2006, 234, 158. | |
dc.identifier.citedreference | S. P. Prete, L. Rossi, P. P. Correale, M. Turriziani, S. Baier, G. Tamburrelli, L. De Vecchis, E. Bonmassar, A. Aquino, Pharmacol. Res. 2005, 52, 167. | |
dc.identifier.citedreference | E. J. Vankampen, W. G. Zijlstra, Adv. Clin. Chem. 1983, 23, 199. | |
dc.identifier.citedreference | C.‐L. Tsai, J.‐C. Chen, W.‐J. Wang, Journal of Medical and Biological Engineering 2001, 21, 7. | |
dc.identifier.citedreference | M. Chen, H. Nam, H. Rokni, S. Wi, J. S. Yoon, P. Chen, K. Kurabayashi, W. Lu, X. Liang, ACS Nano 2015, 9, 8773. | |
dc.identifier.citedreference | Y. Zhihao, O. Zhun‐Yong, L. Songlin, X. Jian‐Bin, Z. Gang, Z. Yong‐Wei, S. Yi, W. Xinran, Adv. Funct. Mater. 2017, 27, 1604093. | |
dc.identifier.citedreference | S. Wi, H. Kim, M. Chen, H. Nam, L. J. Guo, E. Meyhofer, X. Liang, ACS Nano 2014, 8, 5270. | |
dc.identifier.citedreference | K. Saha, S. S. Agasti, C. Kim, X. Li, V. M. Rotello, Chem. Rev. 2012, 112, 2739. | |
dc.identifier.citedreference | K. A. Willets, R. P. V. Duyne, Annu. Rev. Phys. Chem. 2007, 58, 267. | |
dc.identifier.citedreference | P. D. Howes, S. Rana, M. M. Stevens, Chem. Soc. Rev. 2014, 43, 3835. | |
dc.identifier.citedreference | L. Tang, J. Li, ACS Sens. 2017, 2, 857. | |
dc.identifier.citedreference | W. Zhou, X. Gao, D. Liu, X. Chen, Chem. Rev. 2015, 115, 10575. | |
dc.identifier.citedreference | Z. Gao, Z. Qiu, M. Lu, J. Shu, D. Tang, Biosens. Bioelectron. 2017, 89, 1006. | |
dc.identifier.citedreference | Z. Gao, M. Xu, L. Hou, G. Chen, D. Tang, Anal. Chem. 2013, 85, 6945. | |
dc.identifier.citedreference | D. A. Giljohann, D. S. Seferos, W. L. Daniel, M. D. Massich, P. C. Patel, C. A. Mirkin, Angew. Chem., Int. Ed. 2010, 49, 3280. | |
dc.identifier.citedreference | R. S. Gaster, D. A. Hall, C. H. Nielsen, S. J. Osterfeld, H. Yu, K. E. Mach, R. J. Wilson, B. Murmann, J. C. Liao, S. S. Gambhir, S. X. Wang, Nat. Med. 2009, 15, 1327. | |
dc.identifier.citedreference | R. M. Nagler, Oral Oncol. 2009, 45, 1006. | |
dc.identifier.citedreference | D. Sidransky, Nat. Rev. Cancer 2002, 2, 210. | |
dc.identifier.citedreference | L. Wu, X. Qu, Chem. Soc. Rev. 2015, 44, 2963. | |
dc.identifier.citedreference | Y. Xianyu, Y. Chen, X. Jiang, Anal. Chem. 2015, 87, 10688. | |
dc.identifier.citedreference | X.‐M. Nie, R. Huang, C.‐X. Dong, L.‐J. Tang, R. Gui, J.‐H. Jiang, Biosens. Bioelectron. 2014, 58, 314. | |
dc.identifier.citedreference | L. Rodríguez‐Lorenzo, R. de la Rica, R. A. Álvarez‐Puebla, L. M. Liz‐Marzán, M. M. Stevens, Nat. Mater. 2012, 11, 604. | |
dc.identifier.citedreference | R. Ren, G. Cai, Z. Yu, D. Tang, Sens. Actuators, B 2018, 265, 174. | |
dc.identifier.citedreference | R. Ren, G. Cai, Z. Yu, Y. Zeng, D. Tang, Anal. Chem. 2018, 90, 11099. | |
dc.working.doi | NO | en |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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