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Viperin—taken down with a pinch of salt

dc.contributor.authorGhosh, Soumi
dc.contributor.authorMarsh, E Neil G
dc.date.accessioned2022-01-06T15:51:46Z
dc.date.available2023-02-06 10:51:46en
dc.date.available2022-01-06T15:51:46Z
dc.date.issued2022-01-05
dc.identifier.citationGhosh, Soumi; Marsh, E Neil G (2022). "Viperin—taken down with a pinch of salt." EMBO reports (1): n/a-n/a.
dc.identifier.issn1469-221X
dc.identifier.issn1469-3178
dc.identifier.urihttps://hdl.handle.net/2027.42/171233
dc.publisherWiley Periodicals, Inc.
dc.titleViperin—taken down with a pinch of salt
dc.typeArticle
dc.rights.robotsIndexNoFollow
dc.subject.hlbsecondlevelMolecular, Cellular and Developmental Biology
dc.subject.hlbtoplevelHealth Sciences
dc.description.peerreviewedPeer Reviewed
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/171233/1/embr202154258_am.pdf
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/171233/2/embr202154258.pdf
dc.identifier.doi10.15252/embr.202154258
dc.identifier.sourceEMBO reports
dc.identifier.citedreferenceMeyer H, Bug M, Bremer S ( 2012 ) Emerging functions of the VCP/p97 AAA‐ATPase in the ubiquitin system. Nat Cell Biol 14: 117 – 123
dc.identifier.citedreferencePatel AM, Marsh ENG ( 2021 ) Viperin activates protein ubiquitination by the e3 ubiquitin ligase, traf6. J Am Chem Soc 143: 4910 – 4914
dc.identifier.citedreferenceBernheim A, Millman A, Ofir G, Meitav G, Avraham C, Shomar H, Rosenberg MM, Tal N, Melamed S, Amitai G et al ( 2021 ) Prokaryotic viperins produce diverse antiviral molecules. Nature 589: 120 – 230
dc.identifier.citedreferenceBroderick JB, Duffus BR, Duschene KS, Shepard EM ( 2014 ) Radical s‐adenosylmethionine enzymes. Chem Rev 114: 4229 – 4317
dc.identifier.citedreferenceChin KC, Cresswell P ( 2001 ) Viperin (cig5), an IFN‐inducible antiviral protein directly induced by human cytomegalovirus. Proc Natl Acad Sci USA 98: 15125 – 15130
dc.identifier.citedreferenceGhosh S, Marsh ENG ( 2020 ) Viperin: an ancient radical SAM enzyme finds its place in modern cellular metabolism and innate immunity. J Biol Chem 295: 11513 – 11528
dc.identifier.citedreferenceGizzi AS, Grove TL, Arnold JJ, Jose J, Jangra RK, Garforth SJ, Du Q, Cahill SM, Dulyaninova NG, Love JD et al ( 2018 ) A naturally occurring antiviral ribonucleotide encoded by the human genome. Nature 558: 610 – 614
dc.identifier.citedreferenceHelbig KJ, Beard MR ( 2014 ) The role of viperin in the innate antiviral response. J Mol Biol 426: 1210 – 1219
dc.identifier.citedreferenceYuan YK, Miao Y, Ren T, Huang F, Qian L, Chen X, Zuo Y, Zhang HG, He J, Qiao C et al ( 2022 ) High salt activates p97 to reduce host antiviral immunity by restricting Viperin induction. EMBO Rep 23: e53466
dc.identifier.citedreferenceYuan Y, Miao Y, Qian L, Zhang Y, Liu C, Liu J, Zuo Y, Feng Q, Guo T, Zhang L et al ( 2020 ) Targeting UBE4A revives viperin protein in epithelium to enhance host antiviral defense. Mol Cell 77: 734 – 747
dc.working.doiNOen
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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