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Social network characteristics moderate associations between cortical thickness and cognitive functioning in older adults

dc.contributor.authorSharifian, Neika
dc.contributor.authorZaheed, Afsara B.
dc.contributor.authorMorris, Emily P.
dc.contributor.authorSol, Ketlyne
dc.contributor.authorManly, Jennifer J.
dc.contributor.authorSchupf, Nicole
dc.contributor.authorMayeux, Richard
dc.contributor.authorBrickman, Adam M.
dc.contributor.authorZahodne, Laura B.
dc.date.accessioned2022-04-08T18:06:15Z
dc.date.available2023-03-08 14:06:13en
dc.date.available2022-04-08T18:06:15Z
dc.date.issued2022-02
dc.identifier.citationSharifian, Neika; Zaheed, Afsara B.; Morris, Emily P.; Sol, Ketlyne; Manly, Jennifer J.; Schupf, Nicole; Mayeux, Richard; Brickman, Adam M.; Zahodne, Laura B. (2022). "Social network characteristics moderate associations between cortical thickness and cognitive functioning in older adults." Alzheimer’s & Dementia 18(2): 339-347.
dc.identifier.issn1552-5260
dc.identifier.issn1552-5279
dc.identifier.urihttps://hdl.handle.net/2027.42/172061
dc.description.abstractIntroductionPrior research suggests that the strength of association between Alzheimer’s disease (AD) pathology and lower cognitive performance is influenced by modifiable psychosocial factors, such as social network size. However, little is known about distinct social relationship types.MethodsThe current cross‐sectional study used data from the Washington Heights‐Inwood Columbia Aging Project to examine whether social network characteristics (i.e., total size, spouse/partner, number of children, other relatives, friends) moderate associations between cortical thickness in regions implicated in AD and cognitive performance.ResultsLower cortical thickness was associated with worse global cognition among individuals with smaller friend networks, but not among individuals with larger friend networks. This pattern of results was most prominent for language and speed/executive functioning.DiscussionLongitudinal and intervention studies are needed to determine whether these cross‐sectional findings reflect a protective effect of later‐life friendships for maintaining cognitive performance in the context of poorer brain health.
dc.publisherPsychological Assessment Resources, Inc.
dc.publisherWiley Periodicals, Inc.
dc.subject.othercognitive reserve
dc.subject.otherpsychosocial
dc.subject.othersocial relations
dc.subject.othercognitive aging
dc.titleSocial network characteristics moderate associations between cortical thickness and cognitive functioning in older adults
dc.typeArticle
dc.rights.robotsIndexNoFollow
dc.subject.hlbsecondlevelNeurology and Neurosciences
dc.subject.hlbtoplevelHealth Sciences
dc.description.peerreviewedPeer Reviewed
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/172061/1/alz12383_am.pdf
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/172061/2/alz12383.pdf
dc.identifier.doi10.1002/alz.12383
dc.identifier.sourceAlzheimer’s & Dementia
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dc.working.doiNOen
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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