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Outcomes after definitive surgery for mandibular osteoradionecrosis
dc.contributor.authorContrera, Kevin J.
dc.contributor.authorChinn, Steven B.
dc.contributor.authorWeber, Randal S.
dc.contributor.authorRoberts, Dianna
dc.contributor.authorMyers, Jeffery N.
dc.contributor.authorLai, Stephen Y.
dc.contributor.authorLewis, Carol M.
dc.contributor.authorHessel, Amy C.
dc.contributor.authorGillenwater, Ann M.
dc.contributor.authorMulcahy, Collin F.
dc.contributor.authorYu, Peirong
dc.contributor.authorHanasono, Matthew M.
dc.contributor.authorFuller, Clifton D.
dc.contributor.authorChambers, Mark S.
dc.contributor.authorZafereo, Mark E.
dc.date.accessioned2022-05-06T17:25:47Z
dc.date.available2023-07-06 13:25:45en
dc.date.available2022-05-06T17:25:47Z
dc.date.issued2022-06
dc.identifier.citationContrera, Kevin J.; Chinn, Steven B.; Weber, Randal S.; Roberts, Dianna; Myers, Jeffery N.; Lai, Stephen Y.; Lewis, Carol M.; Hessel, Amy C.; Gillenwater, Ann M.; Mulcahy, Collin F.; Yu, Peirong; Hanasono, Matthew M.; Fuller, Clifton D.; Chambers, Mark S.; Zafereo, Mark E. (2022). "Outcomes after definitive surgery for mandibular osteoradionecrosis." Head & Neck 44(6): 1313-1323.
dc.identifier.issn1043-3074
dc.identifier.issn1097-0347
dc.identifier.urihttps://hdl.handle.net/2027.42/172253
dc.description.abstractObjectivesTo analyze charges, complications, survival, and functional outcomes for definitive surgery of mandibular osteoradionecrosis (ORN).Materials and MethodsRetrospective analysis of 76 patients who underwent segmental mandibulectomy with reconstruction from 2000 to 2009.ResultsComplications occurred in 49 (65%) patients and were associated with preoperative drainage (odds ratio [OR] 4.40, 95% confidence interval [CI] 1.01–19.27). The adjusted median charge was $343 000, and higher charges were associated with double flap reconstruction (OR 8.15, 95% CI 2.19–30.29) and smoking (OR 5.91, 95% CI 1.69–20.72). Improved swallow was associated with age <67 years (OR 3.76, 95% CI 1.16–12.17) and preoperative swallow (OR 3.42, 95% CI 1.23–9.51). Five-year ORN-recurrence-free survival was 93% while overall survival was 63% and associated with pulmonary disease (HR [hazard ratio] 3.57, 95% CI 1.43–8.94).ConclusionsAlthough recurrence of ORN is rare, surgical complications are common and charges are high. Poorer outcomes and higher charges are associated with preoperative factors.
dc.publisherJohn Wiley & Sons, Inc.
dc.subject.otheroutcomes
dc.subject.othersurvival
dc.subject.othermandibular
dc.subject.otherosteoradionecrosis
dc.subject.otherhospital charges
dc.titleOutcomes after definitive surgery for mandibular osteoradionecrosis
dc.typeArticle
dc.rights.robotsIndexNoFollow
dc.subject.hlbsecondlevelOtolaryngology
dc.subject.hlbtoplevelHealth Sciences
dc.description.peerreviewedPeer Reviewed
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/172253/1/hed27024_am.pdf
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/172253/2/hed27024.pdf
dc.identifier.doi10.1002/hed.27024
dc.identifier.sourceHead & Neck
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dc.working.doiNOen
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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