Show simple item record

Center variations in patient selection for simultaneous heart-kidney transplantation

dc.contributor.authorShaw, Brian I.
dc.contributor.authorSamoylova, Marya L.
dc.contributor.authorBarbas, Andrew S.
dc.contributor.authorCheng, Xingxing S.
dc.contributor.authorLu, Yee
dc.contributor.authorMcElroy, Lisa M.
dc.contributor.authorSanoff, Scott
dc.date.accessioned2022-06-01T20:31:18Z
dc.date.available2023-06-01 16:31:17en
dc.date.available2022-06-01T20:31:18Z
dc.date.issued2022-05
dc.identifier.citationShaw, Brian I.; Samoylova, Marya L.; Barbas, Andrew S.; Cheng, Xingxing S.; Lu, Yee; McElroy, Lisa M.; Sanoff, Scott (2022). "Center variations in patient selection for simultaneous heart-kidney transplantation." Clinical Transplantation 36(5): n/a-n/a.
dc.identifier.issn0902-0063
dc.identifier.issn1399-0012
dc.identifier.urihttps://hdl.handle.net/2027.42/172855
dc.description.abstractThere are no established regulations governing patient selection for simultaneous heart-kidney (SHK) transplantation, creating the potential for significant center-level variations in clinical practice.MethodsUsing the United Network for Organ Sharing (UNOS) Standard Transplant Analysis and Research (STAR) file, we examined practice trends and variations in patient selection for SHK at the center level between January 1, 2004 and March 31, 2019.ResultsOverall, SHK is becoming more common with most centers performing heart transplants also performing SHK. Among patients who underwent heart transplant who were receiving dialysis, the rate of SHK varied from 22% to 86% at the center level. Among patients not on dialysis, the median estimated glomerular filtration rate (eGFR) of patients receiving SHK varied between 19 and 59 mL/min/1.73 m2. When adjusting for other factors, the odds of SHK varied 57-fold between the highest and lowest SHK performing centers.ConclusionVariation in SHK at the center level suggests the need for national guidelines around the selection of patients for SHK.
dc.publisherWiley Periodicals, Inc.
dc.subject.otherwaitlist management
dc.subject.otherUnited Network for Organ Sharing
dc.subject.otherorgan allocation
dc.subject.othermulti-organ transplant
dc.titleCenter variations in patient selection for simultaneous heart-kidney transplantation
dc.typeArticle
dc.rights.robotsIndexNoFollow
dc.subject.hlbsecondlevelMedicine (General)
dc.subject.hlbtoplevelHealth Sciences
dc.description.peerreviewedPeer Reviewed
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/172855/1/ctr14619.pdf
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/172855/2/ctr14619_am.pdf
dc.identifier.doi10.1111/ctr.14619
dc.identifier.sourceClinical Transplantation
dc.identifier.citedreferenceMehra MR, Canter CE, Hannan MM, et al. The 2016 International Society for Heart Lung Transplantation listing criteria for heart transplantation: a 10-year update. J Heart Lung Transplant. 2016; 35 ( 1 ): 1 – 23. https://doi.org/10.1016/j.healun.2015.10.023
dc.identifier.citedreferenceHalpern SE, McConnell A, Peskoe SB, et al. A three-tier system for evaluation of organ procurement organizations’ willingness to pursue and utilize nonideal donor lungs. Am J Transplant. 2021; 21 ( 3 ): 1269 – 1277. https://doi.org/10.1111/ajt.16347
dc.identifier.citedreferenceChoi AY, Mulvihill MS, Lee H-J, et al. Transplant center variability in organ offer acceptance and mortality among US patients on the heart transplant waitlist. JAMA Cardiol. 2020; 5 ( 6 ): 660 – 668. https://doi.org/10.1001/jamacardio.2020.0659
dc.identifier.citedreferenceLuo X, Massie AB, Haugen CE, et al. Baseline and center-level variation in simultaneous liver-kidney listing in the United States. Transplantation. 2018; 102 ( 4 ): 609 – 615. https://doi.org/10.1097/tp.0000000000001984
dc.identifier.citedreferenceUNOS/OPTN. Simultaneous Liver Kidney (SLK) Policy. https://optn.transplant.hrsa.gov/media/1192/0815-12_SLK_Allocation.pdf. Accessed February 24, 2022.
dc.identifier.citedreferenceThe Final Rule. Accessed April 30, 2021. https://www.ecfr.gov/cgi-bin/text-idx?SID=bb60e0a7222f4086a88c31211cac77d1&mc=true&node=pt42.1.121&rgn=div5
dc.identifier.citedreferenceKobashigawa J, Dadhania DM, Farr M, et al. Consensus conference on heart-kidney transplantation. Am J Transplant. 2021; 21 ( 7 ): 2459 – 2467. https://doi.org/10.1111/ajt.16512
dc.identifier.citedreferenceShaw BI, Sudan DL, Boulware LE, McElroy LM. Striking a balance in simultaneous heart kidney transplant: optimizing outcomes for all wait-listed patients. J Am Soc Nephrol. 2020; 31 ( 8 ): 1661 – 1664. https://doi.org/10.1681/asn.2020030336
dc.identifier.citedreferenceShaw BI, Samoylova ML, Sanoff S, et al. Need for improvements in simultaneous heart-kidney allocation: the limitation of pretransplant glomerular filtration rate. Am J Transplant. 2020; 21 ( 7 ): 2468 – 2478. https://doi.org/10.1111/ajt.16466
dc.identifier.citedreferenceCheng XS, Han J, Stedman MR, Chertow GM, Tan JC. And then there were three: effects of pretransplant dialysis on multiorgan transplantation. Transplant Direct. 2021; 7 ( 2 ): e657. https://doi.org/10.1097/txd.0000000000001112
dc.identifier.citedreferenceRecipients SRoT. FAQs: For Transplant Professionals: Program Specific Report Methodology – Posttransplant. Accessed December 4, 2021, https://www.srtr.org/faqs/for-transplant-center-professionals/#ptxcohortlisting
dc.identifier.citedreferenceOPTN. Policy 6: Allocation of Hearts and Heart-Lungs. Accessed December 4, 2021, https://optn.transplant.hrsa.gov/media/eavh5bf3/optn_policies.pdf
dc.identifier.citedreferenceReese PP, Veatch RM, Abt PL, Amaral S. Revisiting multi-organ transplantation in the setting of scarcity. Am J Transpl. 2014; 14 ( 1 ): 21 – 26. https://doi.org/10.1111/ajt.12557
dc.identifier.citedreferenceWestphal SG, Langewisch ED, Robinson AM, et al. The impact of multi-organ transplant allocation priority on waitlisted kidney transplant candidates. Am J Transpl. 2021; 21 ( 6 ): 2161 – 2174. https://doi.org/10.1111/ajt.16390
dc.identifier.citedreferenceWilk AR, Booker SE, Stewart DE, et al. Developing simultaneous liver-kidney transplant medical eligibility criteria while providing a safety net: a 2-year review of the OPTN’s allocation policy. Am J Transpl. 2021; 21 ( 11 ): 3593 – 3607. https://doi.org/10.1111/ajt.16761
dc.identifier.citedreferenceSamoylova ML, Wegermann K, Shaw BI, et al. The impact of the 2017 kidney allocation policy change on simultaneous liver-kidney utilization and outcomes. Liver Transpl. 2021; 27 ( 8 ): 1106 – 1115. https://doi.org/10.1002/lt.26053
dc.identifier.citedreferenceNagai S, Suzuki Y, Kitajima T, et al. Paradigm change in liver transplantation practice after the implementation of the liver-kidney allocation policy. Liver Transpl. 2021; 27 ( 11 ): 1563 – 1576. https://doi.org/10.1002/lt.26107
dc.identifier.citedreferenceBatra RK, Ariyamuthu VK, MacConmara MP, Gupta G, Gungor AB, Tanriover B. Outcomes of simultaneous liver-kidney transplant using kidneys of deceased donors with acute kidney injury. Liver Transpl. 2022. https://doi.org/10.1002/lt.26406
dc.identifier.citedreferenceInker LA, Eneanya ND, Coresh J, et al. New creatinine- and cystatin C-based equations to estimate GFR without race. N Engl J Med. 2021; 385 ( 19 ): 1737 – 1749. https://doi.org/10.1056/NEJMoa2102953
dc.identifier.citedreferenceGander JC, Zhang X, Ross K, et al. Association between dialysis facility ownership and access to kidney transplantation. JAMA. 2019; 322 ( 10 ): 957 – 973. https://doi.org/10.1001/jama.2019.12803
dc.identifier.citedreferenceGander JC, Zhang X, Plantinga L, et al. Racial disparities in preemptive referral for kidney transplantation in Georgia. Clin Transplant. 2018; 32 ( 9 ): e13380. https://doi.org/10.1111/ctr.13380
dc.identifier.citedreferenceLaskey HL, Schomaker N, Hung KW, et al. Predicting renal recovery after liver transplant with severe pretransplant subacute kidney injury: the impact of warm ischemia time. Liver Transpl. 2016; 22 ( 8 ): 1085 – 1091. https://doi.org/10.1002/lt.24488
dc.identifier.citedreferenceWesselman H, Ford CG, Leyva Y, et al. Social determinants of health and race disparities in kidney transplant. Clin J Am Soc Nephrol. 2021; 16 ( 2 ): 262 – 274. https://doi.org/10.2215/cjn.04860420
dc.identifier.citedreferenceNg Y-H, Pankratz VS, Leyva Y, et al. Does racial disparity in kidney transplant waitlisting persist after accounting for social determinants of health? Transplantation. 2020; 104 ( 7 ): 1445 – 1455.
dc.identifier.citedreferenceGoldstein BA, Thomas L, Zaroff JG, Nguyen J, Menza R, Khush KK. Assessment of heart transplant waitlist time and pre- and post-transplant failure: a mixed methods approach. Epidemiology. 2016; 27 ( 4 ): 469 – 476. https://doi.org/10.1097/ede.0000000000000472
dc.identifier.citedreferenceGoldberg DS, French B, Lewis JD, et al. Liver transplant center variability in accepting organ offers and its impact on patient survival. J Hepatol. 2016; 64 ( 4 ): 843 – 851.
dc.identifier.citedreferenceNazzal M, Lentine KL, Naik AS, et al. Center-driven and clinically driven variation in US liver transplant maintenance immunosuppression therapy: a national practice patterns analysis. Transpl Direct. 2018; 4 ( 7 ): e364. https://doi.org/10.1097/txd.0000000000000800
dc.identifier.citedreferenceKwong AJ, Flores A, Saracino G, et al. Center variation in intention-to-treat survival among patients listed for liver transplant. Liver Transpl. 2020; 26 ( 12 ): 1582 – 1593. https://doi.org/10.1002/lt.25852
dc.identifier.citedreferenceMooney JJ, Weill D, Boyd JH, Nicolls MR, Bhattacharya J, Dhillon GS. Effect of transplant center volume on cost and readmissions in medicare lung transplant recipients. Ann Am Thorac Soc. 2016; 13 ( 7 ): 1034 – 1041. https://doi.org/10.1513/AnnalsATS.201601-017OC
dc.identifier.citedreferenceThabut G, Christie JD, Kremers WK, Fournier M, Halpern SD. Survival differences following lung transplantation among US transplant centers. JAMA. 2010; 304 ( 1 ): 53 – 60. https://doi.org/10.1001/jama.2010.885
dc.identifier.citedreferenceTsampalieros A, Knoll GA, Fergusson N, Bennett A, Taljaard M, Fergusson D. Center variation and the effect of center and provider characteristics on clinical outcomes in kidney transplantation: a systematic review of the evidence. Can J Kidney Health Dis. 2017; 4: 2054358117735523. https://doi.org/10.1177/2054358117735523
dc.identifier.citedreferenceKing KL, Husain SA, Schold JD, et al. Major variation across local transplant centers in probability of kidney transplant for wait-listed patients. J Am Soc Nephrol. 2020; 31 ( 12 ): 2900 – 2911. https://doi.org/10.1681/asn.2020030335
dc.identifier.citedreferenceParker WF, Anderson AS, Hedeker D, et al. Geographic variation in the treatment of U.S. adult heart transplant candidates. J Am Coll Cardiol. 2018; 71 ( 16 ): 1715 – 1725. https://doi.org/10.1016/j.jacc.2018.02.030
dc.identifier.citedreferenceAkintoye E, Shin D, Alvarez P, Briasoulis A. State-level variation in waitlist mortality and transplant outcomes among patients listed for heart transplantation in the US from 2011 to 2016. JAMA Netw Open. 2020; 3 ( 12 ): e2028459.
dc.working.doiNOen
dc.owningcollnameInterdisciplinary and Peer-Reviewed


Files in this item

Show simple item record

Remediation of Harmful Language

The University of Michigan Library aims to describe library materials in a way that respects the people and communities who create, use, and are represented in our collections. Report harmful or offensive language in catalog records, finding aids, or elsewhere in our collections anonymously through our metadata feedback form. More information at Remediation of Harmful Language.

Accessibility

If you are unable to use this file in its current format, please select the Contact Us link and we can modify it to make it more accessible to you.