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Pronounced squamous cell contamination in biliary tract cytology: A diagnostic pitfall
dc.contributor.authorTomm, Nicole K.
dc.contributor.authorLamps, Laura W.
dc.contributor.authorKo, Christopher
dc.contributor.authorKwon, Richard S.
dc.contributor.authorCantley, Richard
dc.contributor.authorPantanowitz, Liron
dc.date.accessioned2022-10-05T15:52:44Z
dc.date.available2023-12-05 11:52:42en
dc.date.available2022-10-05T15:52:44Z
dc.date.issued2022-11
dc.identifier.citationTomm, Nicole K.; Lamps, Laura W.; Ko, Christopher; Kwon, Richard S.; Cantley, Richard; Pantanowitz, Liron (2022). "Pronounced squamous cell contamination in biliary tract cytology: A diagnostic pitfall." Diagnostic Cytopathology 50(11): E320-E324.
dc.identifier.issn8755-1039
dc.identifier.issn1097-0339
dc.identifier.urihttps://hdl.handle.net/2027.42/174946
dc.description.abstractSquamous cells are rarely found in biliary tract cytology specimens, and when present are typically scant in quantity. Over an 8-year time period, two cases at our institution reporting abundant squamous cells were identified. Both patients underwent endoscopic retrograde cholangiopancreatography with bile duct brushings and removal of a migrated biliary stent. The migrated stents were retrieved using rat toothed forceps and required removal of the endoscope through the esophagus with the stent exposed to esophageal and oral mucosa outside of the endoscope. Cytologic examination of the accompanying biliary stent material accordingly revealed abundant benign squamous cells. However, bile duct brushings showed benign ductal epithelial cells without squamous cells. Prior and subsequent cytology and bile duct surgical pathology specimens did not show squamous metaplasia. Migrated biliary stents that require endoscopic withdrawal increase the risk of contaminating samples with squamous cells. Recognition of this unique scenario is important, as the differential diagnosis includes squamous metaplasia and squamous neoplasia.
dc.publisherJohn Wiley & Sons, Inc.
dc.subject.otherbile duct
dc.subject.othercontamination
dc.subject.othercytology
dc.subject.otherendoscopy
dc.subject.othermetaplasia
dc.subject.othersquamous cells
dc.titlePronounced squamous cell contamination in biliary tract cytology: A diagnostic pitfall
dc.typeArticle
dc.rights.robotsIndexNoFollow
dc.subject.hlbsecondlevelPathology
dc.subject.hlbtoplevelHealth Sciences
dc.description.peerreviewedPeer Reviewed
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/174946/1/dc25008_am.pdf
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/174946/2/dc25008.pdf
dc.identifier.doi10.1002/dc.25008
dc.identifier.sourceDiagnostic Cytopathology
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dc.working.doiNOen
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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