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Falls are an underappreciated driver of morbidity and mortality in cirrhosis
dc.contributor.authorHa, Albert
dc.contributor.authorSaleh, Zachary M.
dc.contributor.authorSerper, Marina
dc.contributor.authorTapper, Elliot B.
dc.date.accessioned2022-12-05T16:40:25Z
dc.date.available2023-12-05 11:40:24en
dc.date.available2022-12-05T16:40:25Z
dc.date.issued2022-11
dc.identifier.citationHa, Albert; Saleh, Zachary M.; Serper, Marina; Tapper, Elliot B. (2022). "Falls are an underappreciated driver of morbidity and mortality in cirrhosis." Clinical Liver Disease (5): 146-150.
dc.identifier.issn2046-2484
dc.identifier.issn2046-2484
dc.identifier.urihttps://hdl.handle.net/2027.42/175216
dc.publisherWiley Periodicals, Inc.
dc.titleFalls are an underappreciated driver of morbidity and mortality in cirrhosis
dc.typeArticle
dc.rights.robotsIndexNoFollow
dc.subject.hlbsecondlevelGastroenterology
dc.subject.hlbtoplevelHealth Sciences
dc.description.peerreviewedPeer Reviewed
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/175216/1/cld1246.pdf
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/175216/2/cld1246_am.pdf
dc.identifier.doi10.1002/cld.1246
dc.identifier.sourceClinical Liver Disease
dc.identifier.citedreferenceMurphy SL, Richardson JK, Blackwood J, Martinez B, Tapper EB. Neurocognitive and muscular capacities are associated with frailty in adults with cirrhosis. Dig Dis Sci. 2020; 65 ( 12 ): 3734 – 43. https://doi.org/10.1007/s10620-020-06099-4
dc.identifier.citedreferenceTapper EB, Zhao Z, Winder GS, Parikh ND. Deprescribing zolpidem reduces falls and fractures in patients with cirrhosis. JHEP Rep. 2022; 4: 100478. https://doi.org/10.1016/j.jhepr.2022.100478
dc.identifier.citedreferenceMoon AM, Singal AG, Tapper EB. Contemporary epidemiology of chronic liver disease and cirrhosis. Clin Gastroenterol Hepatol. 2020; 18 ( 12 ): 2650 – 66. https://doi.org/10.1016/j.cgh.2019.07.060
dc.identifier.citedreferenceRomán E, Córdoba J, Torrens M, Torras X, Villanueva C, Vargas V, et al. Minimal hepatic encephalopathy is associated with falls. Am J Gastroenterol. 2011; 106 ( 3 ): 476 – 82. https://doi.org/10.1038/ajg.2010.413
dc.identifier.citedreferenceSoriano G, Román E, Córdoba J, Torrens M, Poca M, Torras X, et al. Cognitive dysfunction in cirrhosis is associated with falls: a prospective study. Hepatology. 2012; 55 ( 6 ): 1922 – 30. https://doi.org/10.1002/hep.25554
dc.identifier.citedreferenceTapper EB, Nikirk S, Parikh ND, Zhao L. Falls are common, morbid, and predictable in patients with cirrhosis. J Hepatol. 2021; 75 ( 3 ): 582 – 8. https://doi.org/10.1016/j.jhep.2021.04.012
dc.identifier.citedreferenceTapper EB, Risech-Neyman Y, Sengupta N. Psychoactive medications increase the risk of falls and fall-related injuries in hospitalized patients with cirrhosis. Clin Gastroenterol Hepatol. 2015; 13 ( 9 ): 1670 – 5. https://doi.org/10.1016/j.cgh.2015.03.019
dc.identifier.citedreferenceEzaz G, Murphy SL, Mellinger J, Tapper EB. Increased morbidity and mortality associated with falls among patients with cirrhosis. Am J Med. 2018; 131 ( 6 ): 645 – 50.e2. https://doi.org/10.1016/j.amjmed.2018.01.026
dc.identifier.citedreferenceOtete H, Deleuran T, Fleming KM, Card T, Aithal GP, Jepsen P, et al. Hip fracture risk in patients with alcoholic cirrhosis: a population-based study using English and Danish data. J Hepatol. 2018; 69 ( 3 ): 697 – 704. https://doi.org/10.1016/j.jhep.2018.04.002
dc.identifier.citedreferenceTsai CF, Liu CJ, Chen TJ, Chu CJ, Lin HC, Lee FY, et al. Increased incidence of orthopedic fractures in cirrhotic patients: a nationwide population-based study. J Hepatol. 2013; 58 ( 4 ): 706 – 14. https://doi.org/10.1016/j.jhep.2012.12.001
dc.identifier.citedreferenceCohen SM, Te HS, Levitsky J. Operative risk of total hip and knee arthroplasty in cirrhotic patients. J Arthroplasty. 2005; 20 ( 4 ): 460 – 6. https://doi.org/10.1016/j.arth.2004.05.004
dc.identifier.citedreferenceTapper EB, Baki J, Parikh ND, Lok AS. Frailty, psychoactive medications, and cognitive dysfunction are associated with poor patient-reported outcomes in cirrhosis. Hepatology. 2019; 69 ( 4 ): 1676 – 85. https://doi.org/10.1002/hep.30336
dc.identifier.citedreferenceMurphy SL, Tapper EB, Blackwood J, Richardson JK. Why do individuals with cirrhosis fall? A mechanistic model for fall assessment, treatment, and research. Dig Dis Sci. 2019; 64 ( 2 ): 316 – 23. https://doi.org/10.1007/s10620-018-5333-8
dc.identifier.citedreferenceUrios A, Mangas-Losada A, Gimenez-Garzó C, González-López O, Giner-Durán R, Serra MA, et al. Altered postural control and stability in cirrhotic patients with minimal hepatic encephalopathy correlate with cognitive deficits. Liver Int. 2017; 37 ( 7 ): 1013 – 22. https://doi.org/10.1111/liv.13345
dc.working.doiNOen
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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