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The genome of the sea urchin Strongylocentrotus purpuratus
dc.contributor.authorSodergren, E
dc.contributor.authorWeinstock, GM
dc.contributor.authorDavidson, EH
dc.contributor.authorCameron, RA
dc.contributor.authorGibbs, RA
dc.contributor.authorAngerer, RC
dc.contributor.authorAngerer, LM
dc.contributor.authorArnone, MI
dc.contributor.authorBurgess, DR
dc.contributor.authorBurke, RD
dc.contributor.authorCoffman, JA
dc.contributor.authorDean, M
dc.contributor.authorElphick, MR
dc.contributor.authorEttensohn, CA
dc.contributor.authorFoltz, KR
dc.contributor.authorHamdoun, A
dc.contributor.authorHynes, RO
dc.contributor.authorKlein, WH
dc.contributor.authorMarzluff, W
dc.contributor.authorMcClay, DR
dc.contributor.authorMorris, RL
dc.contributor.authorMushegian, A
dc.contributor.authorRast, JP
dc.contributor.authorSmith, LC
dc.contributor.authorThorndyke, MC
dc.contributor.authorVacquier, VD
dc.contributor.authorWessel, GM
dc.contributor.authorWray, G
dc.contributor.authorZhang, L
dc.contributor.authorElsik, CG
dc.contributor.authorErmolaeva, O
dc.contributor.authorHlavina, W
dc.contributor.authorHofmann, G
dc.contributor.authorKitts, P
dc.contributor.authorLandrum, MJ
dc.contributor.authorMackey, AJ
dc.contributor.authorMaglott, D
dc.contributor.authorPanopoulou, G
dc.contributor.authorPoustka, AJ
dc.contributor.authorPruitt, K
dc.contributor.authorSapojnikov, V
dc.contributor.authorSong, X
dc.contributor.authorSouvorov, A
dc.contributor.authorSolovyev, V
dc.contributor.authorWei, Z
dc.contributor.authorWhittaker, CA
dc.contributor.authorWorley, K
dc.contributor.authorDurbin, KJ
dc.contributor.authorShen, Y
dc.contributor.authorFedrigo, O
dc.contributor.authorGarfield, D
dc.contributor.authorHaygood, R
dc.contributor.authorPrimus, A
dc.contributor.authorSatija, R
dc.contributor.authorSeverson, T
dc.contributor.authorGonzalez-Garay, ML
dc.contributor.authorJackson, AR
dc.contributor.authorMilosavljevic, A
dc.contributor.authorTong, M
dc.contributor.authorKillian, CE
dc.contributor.authorLivingston, BT
dc.contributor.authorWilt, FH
dc.contributor.authorAdams, N
dc.contributor.authorBellé, R
dc.contributor.authorCarbonneau, S
dc.contributor.authorCheung, R
dc.contributor.authorCormier, P
dc.contributor.authorCosson, B
dc.contributor.authorCroce, J
dc.contributor.authorFernandez-Guerra, A
dc.contributor.authorGenevière, AM
dc.contributor.authorGoel, M
dc.contributor.authorKelkar, H
dc.contributor.authorMorales, J
dc.contributor.authorMulner-Lorillon, O
dc.contributor.authorRobertson, AJ
dc.contributor.authorGoldstone, JV
dc.contributor.authorCole, B
dc.contributor.authorEpel, D
dc.contributor.authorGold, B
dc.contributor.authorHahn, ME
dc.contributor.authorHoward-Ashby, M
dc.contributor.authorScally, M
dc.contributor.authorStegeman, JJ
dc.contributor.authorAllgood, EL
dc.contributor.authorCool, J
dc.contributor.authorJudkins, KM
dc.contributor.authorMcCafferty, SS
dc.contributor.authorMusante, AM
dc.contributor.authorObar, RA
dc.contributor.authorRawson, AP
dc.contributor.authorRossetti, BJ
dc.contributor.authorGibbons, IR
dc.contributor.authorHoffman, MP
dc.contributor.authorLeone, A
dc.contributor.authorIstrail, S
dc.contributor.authorMaterna, SC
dc.contributor.authorSamanta, MP
dc.contributor.authorStolc, V
dc.contributor.authorTongprasit, W
dc.coverage.spatialUnited States
dc.date.accessioned2023-01-09T19:21:38Z
dc.date.available2023-01-09T19:21:38Z
dc.date.issued2006-11-10
dc.identifier.issn0036-8075
dc.identifier.issn1095-9203
dc.identifier.urihttps://www.ncbi.nlm.nih.gov/pubmed/17095691
dc.identifier.urihttps://hdl.handle.net/2027.42/175382en
dc.description.abstractWe report the sequence and analysis of the 814-megabase genome of the sea urchin Strongylocentrotus purpuratus, a model for developmental and systems biology. The sequencing strategy combined whole-genome shotgun and bacterial artificial chromosome (BAC) sequences. This use of BAC clones, aided by a pooling strategy, overcame difficulties associated with high heterozygosity of the genome. The genome encodes about 23,300 genes, including many previously thought to be vertebrate innovations or known only outside the deuterostomes. This echinoderm genome provides an evolutionary outgroup for the chordates and yields insights into the evolution of deuterostomes.
dc.format.mediumPrint
dc.languageeng
dc.publisherAmerican Association for the Advancement of Science (AAAS)
dc.subjectAnimals
dc.subjectCalcification, Physiologic
dc.subjectCell Adhesion Molecules
dc.subjectComplement Activation
dc.subjectComputational Biology
dc.subjectEmbryonic Development
dc.subjectEvolution, Molecular
dc.subjectGene Expression Regulation, Developmental
dc.subjectGenes
dc.subjectGenome
dc.subjectImmunity, Innate
dc.subjectImmunologic Factors
dc.subjectMale
dc.subjectNervous System Physiological Phenomena
dc.subjectProteins
dc.subjectSequence Analysis, DNA
dc.subjectSignal Transduction
dc.subjectStrongylocentrotus purpuratus
dc.subjectTranscription Factors
dc.titleThe genome of the sea urchin Strongylocentrotus purpuratus
dc.typeArticle
dc.identifier.pmid17095691
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/175382/2/nihms-240032.pdf
dc.identifier.doi10.1126/science.1133609
dc.identifier.doihttps://dx.doi.org/10.7302/6763
dc.identifier.sourceScience
dc.description.versionPublished version
dc.date.updated2023-01-09T19:21:37Z
dc.description.filedescriptionDescription of nihms-240032.pdf : Published version
dc.identifier.volume314
dc.identifier.issue5801
dc.identifier.startpage941
dc.identifier.endpage952
dc.identifier.name-orcidSodergren, E
dc.identifier.name-orcidWeinstock, GM
dc.identifier.name-orcidDavidson, EH
dc.identifier.name-orcidCameron, RA
dc.identifier.name-orcidGibbs, RA
dc.identifier.name-orcidAngerer, RC
dc.identifier.name-orcidAngerer, LM
dc.identifier.name-orcidArnone, MI
dc.identifier.name-orcidBurgess, DR
dc.identifier.name-orcidBurke, RD
dc.identifier.name-orcidCoffman, JA
dc.identifier.name-orcidDean, M
dc.identifier.name-orcidElphick, MR
dc.identifier.name-orcidEttensohn, CA
dc.identifier.name-orcidFoltz, KR
dc.identifier.name-orcidHamdoun, A
dc.identifier.name-orcidHynes, RO
dc.identifier.name-orcidKlein, WH
dc.identifier.name-orcidMarzluff, W
dc.identifier.name-orcidMcClay, DR
dc.identifier.name-orcidMorris, RL
dc.identifier.name-orcidMushegian, A
dc.identifier.name-orcidRast, JP
dc.identifier.name-orcidSmith, LC
dc.identifier.name-orcidThorndyke, MC
dc.identifier.name-orcidVacquier, VD
dc.identifier.name-orcidWessel, GM
dc.identifier.name-orcidWray, G
dc.identifier.name-orcidZhang, L
dc.identifier.name-orcidElsik, CG
dc.identifier.name-orcidErmolaeva, O
dc.identifier.name-orcidHlavina, W
dc.identifier.name-orcidHofmann, G
dc.identifier.name-orcidKitts, P
dc.identifier.name-orcidLandrum, MJ
dc.identifier.name-orcidMackey, AJ
dc.identifier.name-orcidMaglott, D
dc.identifier.name-orcidPanopoulou, G
dc.identifier.name-orcidPoustka, AJ
dc.identifier.name-orcidPruitt, K
dc.identifier.name-orcidSapojnikov, V
dc.identifier.name-orcidSong, X
dc.identifier.name-orcidSouvorov, A
dc.identifier.name-orcidSolovyev, V
dc.identifier.name-orcidWei, Z
dc.identifier.name-orcidWhittaker, CA
dc.identifier.name-orcidWorley, K
dc.identifier.name-orcidDurbin, KJ
dc.identifier.name-orcidShen, Y
dc.identifier.name-orcidFedrigo, O
dc.identifier.name-orcidGarfield, D
dc.identifier.name-orcidHaygood, R
dc.identifier.name-orcidPrimus, A
dc.identifier.name-orcidSatija, R
dc.identifier.name-orcidSeverson, T
dc.identifier.name-orcidGonzalez-Garay, ML
dc.identifier.name-orcidJackson, AR
dc.identifier.name-orcidMilosavljevic, A
dc.identifier.name-orcidTong, M
dc.identifier.name-orcidKillian, CE
dc.identifier.name-orcidLivingston, BT
dc.identifier.name-orcidWilt, FH
dc.identifier.name-orcidAdams, N
dc.identifier.name-orcidBellé, R
dc.identifier.name-orcidCarbonneau, S
dc.identifier.name-orcidCheung, R
dc.identifier.name-orcidCormier, P
dc.identifier.name-orcidCosson, B
dc.identifier.name-orcidCroce, J
dc.identifier.name-orcidFernandez-Guerra, A
dc.identifier.name-orcidGenevière, AM
dc.identifier.name-orcidGoel, M
dc.identifier.name-orcidKelkar, H
dc.identifier.name-orcidMorales, J
dc.identifier.name-orcidMulner-Lorillon, O
dc.identifier.name-orcidRobertson, AJ
dc.identifier.name-orcidGoldstone, JV
dc.identifier.name-orcidCole, B
dc.identifier.name-orcidEpel, D
dc.identifier.name-orcidGold, B
dc.identifier.name-orcidHahn, ME
dc.identifier.name-orcidHoward-Ashby, M
dc.identifier.name-orcidScally, M
dc.identifier.name-orcidStegeman, JJ
dc.identifier.name-orcidAllgood, EL
dc.identifier.name-orcidCool, J
dc.identifier.name-orcidJudkins, KM
dc.identifier.name-orcidMcCafferty, SS
dc.identifier.name-orcidMusante, AM
dc.identifier.name-orcidObar, RA
dc.identifier.name-orcidRawson, AP
dc.identifier.name-orcidRossetti, BJ
dc.identifier.name-orcidGibbons, IR
dc.identifier.name-orcidHoffman, MP
dc.identifier.name-orcidLeone, A
dc.identifier.name-orcidIstrail, S
dc.identifier.name-orcidMaterna, SC
dc.identifier.name-orcidSamanta, MP
dc.identifier.name-orcidStolc, V
dc.identifier.name-orcidTongprasit, W
dc.working.doi10.7302/6763en
dc.owningcollnameInternal Medicine, Department of


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