View Item 

Show simple item record

Neurotization of the radial forearm free flap improves swallowing outcomes in hemiglossectomy defects
dc.contributor.authorMarchiano, Emily
dc.contributor.authorKana, Lulia
dc.contributor.authorBellile, Emily
dc.contributor.authorSmith, Joshua D.
dc.contributor.authorCasper, Keith A.
dc.contributor.authorMalloy, Kelly M.
dc.contributor.authorChinn, Steven B.
dc.contributor.authorStucken, Chaz L.
dc.contributor.authorPrince, Mark E. P.
dc.contributor.authorChepeha, Douglas B.
dc.contributor.authorRosko, Andrew J.
dc.contributor.authorSpector, Matthew E.
dc.date.accessioned2023-04-04T17:38:39Z
dc.date.available2024-05-04 13:38:38en
dc.date.available2023-04-04T17:38:39Z
dc.date.issued2023-04
dc.identifier.citationMarchiano, Emily; Kana, Lulia; Bellile, Emily; Smith, Joshua D.; Casper, Keith A.; Malloy, Kelly M.; Chinn, Steven B.; Stucken, Chaz L.; Prince, Mark E. P.; Chepeha, Douglas B.; Rosko, Andrew J.; Spector, Matthew E. (2023). "Neurotization of the radial forearm free flap improves swallowing outcomes in hemiglossectomy defects." Head & Neck 45(4): 798-805.
dc.identifier.issn1043-3074
dc.identifier.issn1097-0347
dc.identifier.urihttps://hdl.handle.net/2027.42/176014
dc.description.abstractBackgroundWe examined the effect of free tissue neurotization on speech and swallowing outcomes for patients undergoing reconstruction of hemiglossectomy defects with a radial forearm free flap (RFFF).MethodsA retrospective study was performed in patients with oral cavity squamous cell carcinoma undergoing a hemiglossectomy and reconstruction with a RFFF. Functional outcomes including nutritional mode, range of liquids and solids, and speech understandability were analyzed 1-year post-treatment.ResultsEighty-four patients were included in this analysis, 41 of whom had neurotized flaps (49%). No significant differences in demographic or clinical variables were seen between the neurotized and non-neurotized groups. On multivariate analysis controlling for BMI, flap area, and N-classification, patients with neurotized flaps were significantly more likely to have normal range of liquids and solids and less likely to have a G-tube.ConclusionsNeurotization of RFFF reconstructing hemiglossectomy defects results in decreased G-tube dependence and improved range of liquids and solids.
dc.publisherJohn Wiley & Sons, Inc.
dc.subject.otheroral cavity
dc.subject.otherneurotization of free flap
dc.subject.otherhemiglossectomy
dc.subject.othernerve graft
dc.subject.othersensate radial forearm free flap
dc.titleNeurotization of the radial forearm free flap improves swallowing outcomes in hemiglossectomy defects
dc.typeArticle
dc.rights.robotsIndexNoFollow
dc.subject.hlbsecondlevelOtolaryngology
dc.subject.hlbtoplevelHealth Sciences
dc.description.peerreviewedPeer Reviewed
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/176014/1/hed27290_am.pdf
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/176014/2/hed27290.pdf
dc.identifier.doi10.1002/hed.27290
dc.identifier.sourceHead & Neck
dc.identifier.citedreferenceChepeha DB, Teknos TN, Shargorodsky J, et al. Rectangle tongue template for reconstruction of the hemiglossectomy defect. Arch Otolaryngol Head Neck Surg. 2008; 134 ( 9 ): 993 - 998.
dc.identifier.citedreferenceEngel H, Huang JJ, Lin CY, et al. A strategic approach for tongue reconstruction to achieve predictable and improved functional and aesthetic outcomes. Plast Reconstr Surg. 2010; 126 ( 6 ): 1967 - 1977.
dc.identifier.citedreferenceBaas M, Duraku LS, Corten EM, Mureau MA. A systematic review on the sensory reinnervation of free flaps for tongue reconstruction: Does improved sensibility imply functional benefits? J Plast Reconstr Aesthet Surg. 2015; 68 ( 8 ): 1025 - 1035.
dc.identifier.citedreferenceChepeha DB, Spector ME, Chinn SB, et al. Hemiglossectomy tongue reconstruction: modeling of elevation, protrusion, and functional outcome using receiver operator characteristic curve. Head Neck. 2016; 38 ( 7 ): 1066 - 1073.
dc.identifier.citedreferenceUrken ML, Weinberg H, Vickery C, Biller HF. The neurofasciocutaneous radial forearm flap in head and neck reconstruction: a preliminary report. Laryngoscope. 1990; 100 ( 2 Pt 1 ): 161 - 173.
dc.identifier.citedreferencePipkorn P, Rosenquist K, Zenga J. Functional considerations in oral cavity reconstruction. Curr Opin Otolaryngol Head Neck Surg. 2018; 26 ( 5 ): 326 - 333.
dc.identifier.citedreferenceMeyer F, Fortin A, Gélinas M, et al. Health-related quality of life as a survival predictor for patients with localized head and neck cancer treated with radiation therapy. J Clin Oncol. 2009; 27 ( 18 ): 2970 - 2976.
dc.identifier.citedreferenceSalibian AH, Allison GR, Armstrong WB, et al. Functional hemitongue reconstruction with the microvascular ulnar forearm flap. Plast Reconstr Surg. 1999; 104 ( 3 ): 654 - 660.
dc.identifier.citedreferenceUrken ML, Biller HF. A new bilobed design for the sensate radial forearm flap to preserve tongue mobility following significant glossectomy. Arch Otolaryngol Head Neck Surg. 1994; 120 ( 1 ): 26 - 31.
dc.identifier.citedreferenceKimata Y, Uchiyama K, Ebihara S, et al. Comparison of innervated and noninnervated free flaps in oral reconstruction. Plast Reconstr Surg. 1999; 104 ( 5 ): 1307 - 1313.
dc.identifier.citedreferenceOzkan O, Ozkan O, Derin AT, et al. True functional reconstruction of total or subtotal glossectomy defects using a chimeric anterolateral thigh flap with both sensorial and motor innervation. Ann Plast Surg. 2015; 74 ( 5 ): 557 - 564.
dc.identifier.citedreferenceYousif NJ, Warren R, Matloub HS, Sanger JR. The lateral arm fascial free flap: its anatomy and use in reconstruction. Plast Reconstr Surg. 1990; 86 ( 6 ): 1138 - 1145; discussion 1146–1137.
dc.identifier.citedreferenceHenry M, Rosberger Z, Bertrand L, et al. Prevalence and risk factors of suicidal ideation among patients with head and neck cancer: longitudinal study. Otolaryngol Head Neck Surg. 2018; 159 ( 5 ): 843 - 852.
dc.identifier.citedreferenceCallahan CM, Buchanan NN, Stump TE. Healthcare costs associated with percutaneous endoscopic gastrostomy among older adults in a defined community. J Am Geriatr Soc. 2001; 49 ( 11 ): 1525 - 1529.
dc.identifier.citedreferenceBoyd B, Mulholland S, Gullane P, et al. Reinnervated lateral antebrachial cutaneous neurosome flaps in oral reconstruction: Are we making sense? Plast Reconstr Surg. 1994; 93 ( 7 ): 1350 - 1359; discussion 1360–1352.
dc.identifier.citedreferenceKapur KK, Garrett NR, Fischer E. Effects of anaesthesia of human oral structures on masticatory performance and food particle size distribution. Arch Oral Biol. 1990; 35 ( 5 ): 397 - 403.
dc.identifier.citedreferenceNamin AW, Varvares MA. Functional outcomes of sensate versus insensate free flap reconstruction in oral and oropharyngeal reconstruction: a systematic review. Head Neck. 2016; 38 ( 11 ): 1717 - 1721.
dc.identifier.citedreferencePaleri V, Patterson J. Use of gastrostomy in head and neck cancer: a systematic review to identify areas for future research. Clin Otolaryngol. 2010; 35 ( 3 ): 177 - 189.
dc.identifier.citedreferenceRogers SN, Thomson R, O’Toole P, Lowe D. Patients experience with long-term percutaneous endoscopic gastrostomy feeding following primary surgery for oral and oropharyngeal cancer. Oral Oncol. 2007; 43 ( 5 ): 499 - 507.
dc.identifier.citedreferenceLydiatt WM, Moran J, Burke WJ. A review of depression in the head and neck cancer patient. Clin Adv Hematol Oncol. 2009; 7 ( 6 ): 397 - 403.
dc.identifier.citedreferenceSantamaria E, Wei FC, Chen IH, Chuang DC. Sensation recovery on innervated radial forearm flap for hemiglossectomy reconstruction by using different recipient nerves. Plast Reconstr Surg. 1999; 103 ( 2 ): 450 - 457.
dc.identifier.citedreferenceNetscher D, Armenta AH, Meade RA, Alford EL. Sensory recovery of innervated and non-innervated radial forearm free flaps: functional implications. J Reconstr Microsurg. 2000; 16 ( 3 ): 179 - 185.
dc.identifier.citedreferenceLoewen IJ, Boliek CA, Harris J, Seikaly H, Rieger JM. Oral sensation and function: a comparison of patients with innervated radial forearm free flap reconstruction to healthy matched controls. Head Neck. 2010; 32 ( 1 ): 85 - 95.
dc.working.doiNOen
dc.owningcollnameInterdisciplinary and Peer-Reviewed


Files in this item

Name:
hed27290_am.pdf
Size:
490.1KB
Format:
PDF
View/Open
Name:
hed27290.pdf
Size:
1.095MB
Format:
PDF
View/Open

Show simple item record

Remediation of Harmful Language

The University of Michigan Library aims to describe library materials in a way that respects the people and communities who create, use, and are represented in our collections. Report harmful or offensive language in catalog records, finding aids, or elsewhere in our collections anonymously through our metadata feedback form. More information at Remediation of Harmful Language.

Accessibility

If you are unable to use this file in its current format, please select the Contact Us link and we can modify it to make it more accessible to you.