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Biomimetic antimicrobial polymers—Design, characterization, antimicrobial, and novel applications
dc.contributor.authorTakahashi, Haruko
dc.contributor.authorSovadinova, Iva
dc.contributor.authorYasuhara, Kazuma
dc.contributor.authorVemparala, Satyavani
dc.contributor.authorCaputo, Gregory A.
dc.contributor.authorKuroda, Kenichi
dc.date.accessioned2023-06-01T20:47:30Z
dc.date.available2024-06-01 16:47:27en
dc.date.available2023-06-01T20:47:30Z
dc.date.issued2023-05
dc.identifier.citationTakahashi, Haruko; Sovadinova, Iva; Yasuhara, Kazuma; Vemparala, Satyavani; Caputo, Gregory A.; Kuroda, Kenichi (2023). "Biomimetic antimicrobial polymers—Design, characterization, antimicrobial, and novel applications." Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology 15(3): n/a-n/a.
dc.identifier.issn1939-5116
dc.identifier.issn1939-0041
dc.identifier.urihttps://hdl.handle.net/2027.42/176805
dc.description.abstractBiomimetic antimicrobial polymers have been an area of great interest as the need for novel antimicrobial compounds grows due to the development of resistance. These polymers were designed and developed to mimic naturally occurring antimicrobial peptides in both physicochemical composition and mechanism of action. These antimicrobial peptide mimetic polymers have been extensively investigated using chemical, biophysical, microbiological, and computational approaches to gain a deeper understanding of the molecular interactions that drive function. These studies have helped inform SARs, mechanism of action, and general physicochemical factors that influence the activity and properties of antimicrobial polymers. However, there are still lingering questions in this field regarding 3D structural patterning, bioavailability, and applicability to alternative targets. In this review, we present a perspective on the development and characterization of several antimicrobial polymers and discuss novel applications of these molecules emerging in the field.This article is categorized under:Therapeutic Approaches and Drug Discovery > Emerging TechnologiesTherapeutic Approaches and Drug Discovery > Nanomedicine for Infectious DiseaseThis review article provides an update on the status of antimicrobial peptide-mimetic polymers and new targets and new methods in the studies of these polymers.
dc.publisherJohn Wiley & Sons, Inc.
dc.subject.othersimulations
dc.subject.otherantimicrobial polymers
dc.subject.othercancer
dc.subject.othercyanobacteria
dc.subject.otherliposome
dc.titleBiomimetic antimicrobial polymers—Design, characterization, antimicrobial, and novel applications
dc.typeArticle
dc.rights.robotsIndexNoFollow
dc.subject.hlbsecondlevelBiomedical Engineering
dc.subject.hlbtoplevelHealth Sciences
dc.description.peerreviewedPeer Reviewed
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/176805/1/wnan1866.pdf
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/176805/2/wnan1866_am.pdf
dc.identifier.doi10.1002/wnan.1866
dc.identifier.sourceWiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology
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