Interproximal implant thread exposure after initial bone remodeling as a risk indicator for peri-implantitis
dc.contributor.author | Ravidà, Andrea | |
dc.contributor.author | Samal, Ankita | |
dc.contributor.author | Qazi, Musa | |
dc.contributor.author | Webber, Liana Preto | |
dc.contributor.author | Wang, Hom-Lay | |
dc.contributor.author | Galindo-Moreno, Pablo | |
dc.contributor.author | Borgnakke, Wenche S. | |
dc.contributor.author | Saleh, Muhammad H. A. | |
dc.date.accessioned | 2023-07-14T13:57:11Z | |
dc.date.available | 2024-07-14 09:57:10 | en |
dc.date.available | 2023-07-14T13:57:11Z | |
dc.date.issued | 2023-06 | |
dc.identifier.citation | Ravidà, Andrea ; Samal, Ankita; Qazi, Musa; Webber, Liana Preto; Wang, Hom-Lay ; Galindo-Moreno, Pablo ; Borgnakke, Wenche S.; Saleh, Muhammad H. A. (2023). "Interproximal implant thread exposure after initial bone remodeling as a risk indicator for peri- implantitis." Journal of Periodontology 94(6): 751-764. | |
dc.identifier.issn | 0022-3492 | |
dc.identifier.issn | 1943-3670 | |
dc.identifier.uri | https://hdl.handle.net/2027.42/177267 | |
dc.description.abstract | BackgroundDue to the clinical challenges involved in successfully treating peri-implantitis, it is imperative to identify patient- and implant-level risk factors for its prevention. The main goal of this retrospective longitudinal radiographic and clinical study was to investigate whether interproximal radiographic implant thread exposure after physiological bone remodeling may be a risk factor for peri-implantitis. The secondary goal was to evaluate several other potential risk indicators.MethodsOf 4325 active dental school patients having implants placed, 165 partially edentulous adults (77 men, 88 women) aged 30–91 with ≥2 years of follow-up upon implant restoration were included. Implants with ≥1 interproximal thread exposed (no bone-to-implant contact) (n = 98, 35%) constituted the test group and those without exposed threads (n = 182, 65%) the control group. Descriptive, binary, and multivariate regression analyses were evaluated for goodness of fit. Wald tests were used to evaluate for significance set at 0.05.ResultsOf the 280 implants (98 test, 182 control), 8 (2.9%) failed over a mean follow-up period of 7.67 (±2.63) years, and 27 implants (19 test, 8 control) developed peri-implantitis, with the exposed group having eight-fold (7.82 times) adjusted greater odds than the non-exposed. The risk increased four-fold (3.77 times) with each thread exposed. No other patient- or implant-related potentially confounding risk factors were identified.ConclusionsExposed interproximal implant threads after physiologic bone remodeling may be an independent risk indicator for incident peri-implantitis. Hence, clinicians should closely monitor patients with implant threads that have no bone-to-implant contact for incident peri-implantitis. | |
dc.publisher | Wiley Periodicals, Inc. | |
dc.subject.other | bone resorption | |
dc.subject.other | periodontics | |
dc.subject.other | radiography | |
dc.subject.other | tooth loss | |
dc.subject.other | dental implants | |
dc.title | Interproximal implant thread exposure after initial bone remodeling as a risk indicator for peri-implantitis | |
dc.type | Article | |
dc.rights.robots | IndexNoFollow | |
dc.subject.hlbsecondlevel | Dentistry | |
dc.subject.hlbtoplevel | Health Sciences | |
dc.description.peerreviewed | Peer Reviewed | |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/177267/1/jper11049.pdf | |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/177267/2/jper11049_am.pdf | |
dc.identifier.doi | 10.1002/JPER.22-0499 | |
dc.identifier.source | Journal of Periodontology | |
dc.identifier.citedreference | World Medical Association. World Medical Association Declaration of Helsinki: ethical principles for medical research involving human subjects. JAMA. 2013; 310: 2191 - 2194. doi: 10.1001/jama.2013.281053 | |
dc.identifier.citedreference | Buser D, Sennerby L, De Bruyn H. Modern implant dentistry based on osseointegration: 50 years of progress, current trends and open questions. Periodontol 2000. 2017; 73: 7 - 21. doi: 10.1111/prd.12185 | |
dc.identifier.citedreference | Abuhussein H, Pagni G, Rebaudi A, Wang HL. The effect of thread pattern upon implant osseointegration. Clin Oral Implants Res. 2010; 21: 129 - 136. doi: 10.1111/j.1600-0501.2009.01800.x | |
dc.identifier.citedreference | Tirone F, Salzano S, Rodi D, Pozzatti L. Three-year evaluation of the influence of implant surfaces on implant failure and peri-implantitis: a double-blind randomized controlled trial with split-mouth design. Int J Oral Maxillofac Implants. 2021; 36: e23 - e30. 10.11607/jomi.8538 | |
dc.identifier.citedreference | Derks J, Schaller D, Håkansson J, Wennström JL, Tomasi C, Berglundh T. Effectiveness of implant therapy analyzed in a Swedish population: prevalence of peri-implantitis. J Dent Res. 2016; 95: 43 - 49. doi: 10.1177/0022034515608832 | |
dc.identifier.citedreference | Rakasevic D, Lazic Z, Soldatovic I, Scepanovic M, Gabric D. Influence of titanium implant macrodesign on peri-implantitis occurrence: a cross-sectional study. Clin Oral Investig. 2022; 26: 5237 - 5246. doi: 10.1007/s00784-022-04492-z | |
dc.identifier.citedreference | Romanos G, Damouras M, Veis AA, Hess P, Schwarz F, Brandt S. Comparison of histomorphometry and microradiography of different implant designs to assess primary implant stability. Clin Implant Dent Relat Res. 2020; 22: 373 - 379. doi: 10.1111/cid.12915 | |
dc.identifier.citedreference | Kligman S, Ren Z, Chung CH, et al. The impact of dental implant surface modifications on osseointegration and biofilm formation. J Clin Med. 2021; 10: 1641. doi: 10.3390/jcm10081641 | |
dc.identifier.citedreference | Aljateeli M, Wang HL. Implant microdesigns and their impact on osseointegration. Implant Dent. 2013; 22: 127 - 132. doi: 10.1097/ID.0b013e318278a90b | |
dc.identifier.citedreference | Stavropoulos A, Bertl K, Winning L, Polyzois I. What is the influence of implant surface characteristics and/or implant material on the incidence and progression of peri-implantitis? a systematic literature review. Clin Oral Implants Res. 2021; 32 (Suppl 21 ): 203 - 229. doi: 10.1111/clr.13859 | |
dc.identifier.citedreference | Do JH. Peri-Implantitis and concomitant perigraftitis of an implant placed in a site that had alveolar ridge preservation three decades earlier: a case report with human histology. Clin Adv Periodontics. 2022; 12: 44 - 50. doi: 10.1002/cap.10181 | |
dc.identifier.citedreference | Jung RE, Herzog M, Wolleb K, Ramel CF, Thoma DS, Hämmerle CH. A randomized controlled clinical trial comparing small buccal dehiscence defects around dental implants treated with guided bone regeneration or left for spontaneous healing. Clin Oral Implants Res. 2017; 28: 348 - 354. doi: 10.1111/clr.12806 | |
dc.identifier.citedreference | World Medical Association. Declaration of Helsinki: recommendations guiding doctors in clinical research; adopted by the 18th World Medical Assembly, Helsinki, Finland, June 1964. https://www.wma.net/wp-content/uploads/2018/07/DoH-Jun1964.pdf | |
dc.identifier.citedreference | World Medical Association. Declaration of Helsinki: recommendations guiding medical doctors in biomedical research involving human subjects; adopted by the 18th World Medical Assembly, Helsinki, Finland, June 1964 and as revised by the 29th World Medical Assembly, Tokyo, Japan, October 1975. https://www.wma.net/wp-content/uploads/2018/07/DoH-Oct1975.pdf | |
dc.identifier.citedreference | Tonetti MS, Greenwell H, Kornman KS. Staging and grading of periodontitis: framework and proposal of a new classification and case definition. J Periodontol. 2018; 89: S159 - S172. doi: 10.1002/jper.18-0006 | |
dc.identifier.citedreference | Albrektsson T, Wennerberg A. Oral implant surfaces: part 1– review focusing on topographic and chemical properties of different surfaces and in vivo responses to them. Int J Prosthodont. 2004; 17: 536 - 543. | |
dc.identifier.citedreference | Doornewaard R, Christiaens V, De Bruyn H, et al. Long-term effect of surface roughness and patients’ factors on crestal bone loss at dental implants; a systematic review and meta-analysis. Clin Implant Dent Relat Res. 2017; 19 ( 2 ): 372 - 399. doi: 10.1111/cid.12457 | |
dc.identifier.citedreference | Pimentel SP, Shiota R, Cirano FR, et al. Occurrence of peri-implant diseases and risk indicators at the patient and implant levels: a multilevel cross-sectional study. J Periodontol. 2018; 89: 1091 - 1100. doi: 10.1002/JPER.17-0599 | |
dc.identifier.citedreference | Chrcanovic BR, Albrektsson T, Wennerberg A. Reasons for failures of oral implants. J Oral Rehabil. 2014; 41: 443 - 476. doi: 10.1111/joor.12157 | |
dc.identifier.citedreference | Monje A, Aranda L, Diaz KT, et al. Impact of maintenance therapy for the prevention of peri-implant diseases: a systematic review and meta-analysis. J Dent Res. 2016; 95: 372 - 379. doi: 10.1177/0022034515622432 | |
dc.identifier.citedreference | de Souza Batista VE, Verri FR, Lemos CAA, et al. Should the restoration of adjacent implants be splinted or nonsplinted? A systematic review and meta-analysis. J Prosthet Dent. 2019; 121: 41 - 51. doi: 10.1016/j.prosdent.2018.03.004 | |
dc.identifier.citedreference | Ravidà A, Tattan M, Askar H, Barootchi S, Tavelli L, Wang HL. Comparison of three different types of implant-supported fixed dental prostheses: a long-term retrospective study of clinical outcomes and cost-effectiveness. Clin Oral Implants Res. 2019; 30: 295 - 305. doi: 10.1111/clr.13415 | |
dc.identifier.citedreference | Dreyer H, Grischke J, Tiede C, et al. Epidemiology and risk factors of peri-implantitis: a systematic review. J Periodontal Res. 2018; 53: 657 - 681. doi: 10.1111/jre.12562 | |
dc.identifier.citedreference | Gunpinar S, Meraci B, Karas M. Analysis of risk indicators for prevalence of peri-implant diseases in Turkish population. Int J Implant Dent. 2020; 6: 19. doi: 10.1186/s40729-020-00215-9 | |
dc.identifier.citedreference | Papi P, Di Murro B, Pranno N, et al. Prevalence of peri-implant diseases among an Italian population of patients with metabolic syndrome: a cross-sectional study. J Periodontol. 2019; 90: 1374 - 1382. doi: 10.1002/JPER.19-0077 | |
dc.identifier.citedreference | Da Silva JD, Kazimiroff J, Papas A, et al. Outcomes of implants and restorations placed in general dental practices: a retrospective study by the Practitioners Engaged in Applied Research and Learning (PEARL) Network. J Am Dent Assoc. 2014; 145: 704 - 713. 10.14219/jada.2014.27 | |
dc.identifier.citedreference | Saleh MH, Galli M, Siqueira R, Vera M, Wang HL, Ravidà A. The prosthetic-biologic connection and its influence on peri-implant health: an overview of the current evidence. Int J Oral Maxillofac Implants. 2022; 37: 690 - 699. doi: 10.11607/jomi.9523 | |
dc.identifier.citedreference | Schwarz F, Derks J, Monje A, Wang HL. Peri-implantitis. J Periodontol. 2018; 89 (Suppl 1 ): S267 - S290. doi: 10.1002/jper.16-0350 | |
dc.identifier.citedreference | Berglundh T, Armitage G, Araujo MG, et al. Peri-implant diseases and conditions: consensus report of Workgroup 4 of the 2017 World Workshop on the classification of periodontal and peri-implant diseases and conditions. J Periodontol. 2018; 89 (Suppl 1 ): S313 - S318. doi: 10.1002/jper.17-0739 | |
dc.identifier.citedreference | Monje A, Kan JY, Borgnakke WS. Impact of local predisposing/precipitating factors and systemic drivers on peri-implant diseases. Clin Implant Dent Relat Res. 2023. doi: 10.1111/cid.13155. In press. | |
dc.identifier.citedreference | Rokaya D, Srimaneepong V, Wisitrasameewon W, Humagain M, Thunyakitpisal P. Peri-implantitis update: risk indicators, diagnosis, and treatment. Eur J Dent. 2020; 14: 672 - 682. doi: 10.1055/s-0040-1715779 | |
dc.identifier.citedreference | Derks J, Tomasi C. Peri-implant health and disease: a systematic review of current epidemiology. J Clin Periodontol. 2015; 42: S158 - S171. doi: 10.1111/jcpe.12334 | |
dc.identifier.citedreference | Diaz P, Gonzalo E, Villagra LJG, Miegimolle B, Suarez MJ. What is the prevalence of peri-implantitis? A systematic review and meta-analysis. BMC Oral Health. 2022; 22: 449. doi: 10.1186/s12903-022-02493-8 | |
dc.identifier.citedreference | Rakic M, Galindo-Moreno P, Monje A, et al. How frequent does peri-implantitis occur? A systematic review and meta-analysis. Clin Oral Investig. 2018; 22: 1805 - 1816. doi: 10.1007/s00784-017-2276-y | |
dc.identifier.citedreference | Renvert S, Hirooka H, Polyzois I, Kelekis-Cholakis A, Wang HL, Working Group 3. Diagnosis and non-surgical treatment of peri-implant diseases and maintenance care of patients with dental implants – consensus report of Working group 3. Int Dent J. 2019; 69 (Suppl 2 ): 12 - 17. doi: 10.1111/idj.12490 | |
dc.identifier.citedreference | Renvert S, Persson GR, Pirih FQ, Camargo PM. Peri-implant health, peri-implant mucositis, and peri-implantitis: case definitions and diagnostic considerations. J Periodontol. 2018; 89 (Suppl 1 ): S304 - S312. doi: 10.1002/JPER.17-0588 | |
dc.identifier.citedreference | Albrektsson T, Dahlin C, Reinedahl D, Tengvall P, Trindade R, Wennerberg A. An imbalance of the immune system instead of a disease behind marginal bone loss around oral implants: position paper. Int J Oral Maxillofac Implants. 2020; 35: 495 - 502. 10.11607/jomi.8218 | |
dc.identifier.citedreference | Roos-Jansåker AM, Renvert H, Lindahl C, Renvert S. Nine- to fourteen-year follow-up of implant treatment. part III: factors associated with peri-implant lesions. J Clin Periodontol. 2006; 33: 296 - 301. doi: 10.1111/j.1600-051X.2006.00908.x | |
dc.identifier.citedreference | Ferreira SD, Silva GL, Cortelli JR, Costa JE, Costa FO. Prevalence and risk variables for peri-implant disease in Brazilian subjects. J Clin Periodontol. 2006; 33: 929 - 935. doi: 10.1111/j.1600-051X.2006.01001.x | |
dc.identifier.citedreference | Pontoriero R, Tonelli MP, Carnevale G, Mombelli A, Nyman SR, Lang NP. Experimentally induced peri-implant mucositis. a clinical study in humans. Clin Oral Implants Res. 1994; 5: 254 - 259. doi: 10.1034/j.1600-0501.1994.050409.x | |
dc.identifier.citedreference | Ravidà A, Siqueira R, Di Gianfilippo R, et al. Prognostic factors associated with implant loss, disease progression or favorable outcomes after peri-implantitis surgical therapy. Clin Implant Dent Relat Res. 2022; 24: 222 - 232. doi: 10.1111/cid.13074 | |
dc.identifier.citedreference | Ravidà A, Rodriguez MV, Saleh MHA, et al. The correlation between history of periodontitis according to staging and grading and the prevalence/severity of peri-implantitis in patients enrolled in maintenance therapy. J Periodontol. 2021; 92: 1522 - 1535. doi: 10.1002/JPER.21-0012 | |
dc.identifier.citedreference | Frisch E, Vach K, Ratka-Krueger P. Impact of supportive implant therapy on peri-implant diseases: a retrospective 7-year study. J Clin Periodontol. 2020; 47: 101 - 109. doi: 10.1111/jcpe.13206 | |
dc.identifier.citedreference | Costa FO, Takenaka-Martinez S, Cota LO, Ferreira SD, Silva GL, Costa JE. Peri-implant disease in subjects with and without preventive maintenance: a 5-year follow-up. J Clin Periodontol. 2012; 39: 173 - 181. doi: 10.1111/j.1600-051X.2011.01819.x | |
dc.identifier.citedreference | Roccuzzo M, Layton DM, Roccuzzo A, Heitz-Mayfield LJ. Clinical outcomes of peri-implantitis treatment and supportive care: a systematic review. Clin Oral Implants Res. 2018; 29 (Suppl 16 ): 331 - 350. doi: 10.1111/clr.13287 | |
dc.identifier.citedreference | Xue T, Attarilar S, Liu S, et al. Surface modification techniques of titanium and its alloys to functionally optimize their biomedical properties: thematic review. Front Bioeng Biotechnol. 2020; 8: 603072. doi: 10.3389/fbioe.2020.603072 | |
dc.identifier.citedreference | Berger MB, Slosar P, Schwartz Z, et al. A review of biomimetic topographies and their role in promoting bone formation and osseointegration: implications for clinical use. Biomimetics (Basel). 2022; 7. doi: 10.3390/biomimetics7020046 | |
dc.identifier.citedreference | Sanz-Martin I, Paeng K, Park H, Cha JK, Jung UW, Sanz M. Significance of implant design on the efficacy of different peri-implantitis decontamination protocols. Clin Oral Investig. 2021; 25: 3589 - 3597. doi: 10.1007/s00784-020-03681-y | |
dc.identifier.citedreference | Bosshardt DD, Chappuis V, Buser D. Osseointegration of titanium, titanium alloy and zirconia dental implants: current knowledge and open questions. Periodontol 2000. 2017; 73: 22 - 40. doi: 10.1111/prd.12179 | |
dc.working.doi | NO | en |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
Files in this item
Remediation of Harmful Language
The University of Michigan Library aims to describe its collections in a way that respects the people and communities who create, use, and are represented in them. We encourage you to Contact Us anonymously if you encounter harmful or problematic language in catalog records or finding aids. More information about our policies and practices is available at Remediation of Harmful Language.
Accessibility
If you are unable to use this file in its current format, please select the Contact Us link and we can modify it to make it more accessible to you.