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Practical algorithms for early diagnosis of heart failure and heart stress using NT-proBNP: A clinical consensus statement from the Heart Failure Association of the ESC

dc.contributor.authorBayes-Genis, Antoni
dc.contributor.authorDocherty, Kieran F.
dc.contributor.authorPetrie, Mark C.
dc.contributor.authorJanuzzi, James L.
dc.contributor.authorMueller, Christian
dc.contributor.authorAnderson, Lisa
dc.contributor.authorBozkurt, Biykem
dc.contributor.authorButler, Javed
dc.contributor.authorChioncel, Ovidiu
dc.contributor.authorCleland, John G.F.
dc.contributor.authorChristodorescu, Ruxandra
dc.contributor.authorDel Prato, Stefano
dc.contributor.authorGustafsson, Finn
dc.contributor.authorLam, Carolyn S.P.
dc.contributor.authorMoura, Brenda
dc.contributor.authorPop-Busui, Rodica
dc.contributor.authorSeferovic, Petar
dc.contributor.authorVolterrani, Maurizio
dc.contributor.authorVaduganathan, Muthiah
dc.contributor.authorMetra, Marco
dc.contributor.authorRosano, Giuseppe
dc.date.accessioned2024-01-04T21:58:26Z
dc.date.available2024-12-04 16:58:24en
dc.date.available2024-01-04T21:58:26Z
dc.date.issued2023-11
dc.identifier.citationBayes-Genis, Antoni ; Docherty, Kieran F.; Petrie, Mark C.; Januzzi, James L.; Mueller, Christian; Anderson, Lisa; Bozkurt, Biykem; Butler, Javed; Chioncel, Ovidiu; Cleland, John G.F.; Christodorescu, Ruxandra; Del Prato, Stefano; Gustafsson, Finn; Lam, Carolyn S.P.; Moura, Brenda; Pop-Busui, Rodica ; Seferovic, Petar; Volterrani, Maurizio; Vaduganathan, Muthiah; Metra, Marco; Rosano, Giuseppe (2023). "Practical algorithms for early diagnosis of heart failure and heart stress using NT- proBNP: A clinical consensus statement from the Heart Failure Association of the ESC." European Journal of Heart Failure 25(11): 1891-1898.
dc.identifier.issn1388-9842
dc.identifier.issn1879-0844
dc.identifier.urihttps://hdl.handle.net/2027.42/191833
dc.description.abstractDiagnosing heart failure is often difficult due to the non-specific nature of symptoms, which can be caused by a range of medical conditions. Natriuretic peptides (NPs) have been recognized as important biomarkers for diagnosing heart failure. This document from the Heart Failure Association examines the practical uses of N-terminal pro-B-type natriuretic peptide (NT-proBNP) in various clinical scenarios. The concentrations of NT-proBNP vary according to the patient profile and the clinical scenario, therefore values should be interpreted with caution to ensure appropriate diagnosis. Validated cut-points are provided to rule in or rule out acute heart failure in the emergency department and to diagnose de novo heart failure in the outpatient setting. We also coin the concept of ‘heart stress’ when NT-proBNP levels are elevated in an asymptomatic patient with risk factors for heart failure (i.e. diabetes, hypertension, coronary artery disease), underlying the development of cardiac dysfunction and further increased risk. We propose a simple acronym for healthcare professionals and patients, FIND-HF, which serves as a prompt to consider heart failure: Fatigue, Increased water accumulation, Natriuretic peptide testing, and Dyspnoea. Use of this acronym would enable the early diagnosis of heart failure. Overall, understanding and utilizing NT-proBNP levels will lead to earlier and more accurate diagnoses of heart failure ultimately improving patient outcomes and reducing healthcare costs.
dc.publisherJohn Wiley & Sons, Ltd.
dc.subject.otherNatriuretic peptides
dc.subject.otherNT-proBNP
dc.subject.otherHeart failure
dc.titlePractical algorithms for early diagnosis of heart failure and heart stress using NT-proBNP: A clinical consensus statement from the Heart Failure Association of the ESC
dc.typeArticle
dc.rights.robotsIndexNoFollow
dc.subject.hlbsecondlevelCardiovascular Medicine
dc.subject.hlbtoplevelHealth Sciences
dc.description.peerreviewedPeer Reviewed
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/191833/1/ejhf3036.pdf
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/191833/2/ejhf3036_am.pdf
dc.identifier.doi10.1002/ejhf.3036
dc.identifier.sourceEuropean Journal of Heart Failure
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dc.working.doiNOen
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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