Now showing items 1-10 of 220
Λ-Dynamics free energy simulation methods
(Wiley Subscription Services, Inc., A Wiley Company, 2009-08)
Free energy calculations are fundamental to obtaining accurate theoretical estimates of many important biological phenomena including hydration energies, protein-ligand binding affinities and energetics of conformational ...
7 th HUPO World Congress of Proteomics: Launching the Second Phase of the HUPO Plasma Proteome Project (PPP-2) 16–20 August 2008, Amsterdam, The Netherlands
(WILEY-VCH Verlag, 2009-01)
The HUPO Plasma Proteome Project new phase, PPP-2, held its initial workshop on 17 August, 2008, at the 7 th World Congress of Proteomics in Amsterdam. Technology platforms, data repositories, informatics, and engagement ...
Effect of Coadsorbed Water on Deep Oxidation Mechanisms: Temperature-Programmed Reactions of Benzene and Hydroxyl on the Pt(111) Surface
(Kluwer Academic Publishers; Plenum Publishing Corporation ; Springer Science+Business Media, 2004-03)
The deep oxidation of benzene by preadsorbed hydroxyl on the Pt(111) surface has been characterized using temperature-programmed reaction spectroscopy. A mechanism for benzene oxidation in the presence of coadsorbed water ...
2-(3-Pyrrolin-1-yl)-1,4-naphthoquinones: Photoactivated Alkylating Agents
(WILEY-VCH Verlag, 2008-09)
The preparation of 2-(3-pyrrolin-1-yl)-1,4-naphthoquinones and a study of their use as photoactivated alkylating agents is reported. The title compounds were easily synthesized by conjugate addition of the corresponding ...
Vapor-based polymer coatings for potential biomedical applications
(John Wiley & Sons, Ltd., 2006-12)
Over the last decade, biology and biotechnology have witnessed an extraordinary development spanning genomics, proteomics, and metabolics. This progress was so rapid and definite that it not only changed the face of modern ...
Proteomics FASTA Archive and Reference Resource
(WILEY-VCH Verlag, 2008-05)
A FASTA file archive and reference resource has been added to ProteomeCommons.org. Motivation for this new functionality derives from two primary sources. The first is the recent FASTA standardization work done by the Human ...
Synthesis of flexible ligands for assembling two metals in close proximity. Magnetic, electrochemical and spectral properties of binuclear copper (II) complexes with different exogenous bridging motifs
(Kluwer Academic Publishers; Springer Science+Business Media, 2003-04)
Binuclear Cu II complexes having new flexible heptadentate ligands 2,6-bis{[bis(3,3′- N , N -dimethylaminopropyl)amino]methyl}-4-bromophenol [HL 1 ], 2,6-bis(3,3′- N , N -dimethylaminopropyl)amino]methyl}-4-methylphenol ...
Role of conformational dynamics in sequence-specific autoantibody•ssDNA recognition
(Wiley Subscription Services, Inc., A Wiley Company, 2007-04-05)
11F8 is a sequence-specific monoclonal anti-ssDNA autoantibody isolated from a lupus prone mouse that forms pathogenic complexes with ssDNA, resulting in kidney damage. Prior studies show that specificity is mediated by a ...
Characterization of nucleic acid higher order structure by gas-phase H/D exchange in a quadrupole-FT-ICR mass spectrometer
(Wiley Subscription Services, Inc., A Wiley Company, 2009-04)
Nucleic acid higher order structure is of intense interest in antisense and antigene strategies toward novel chemotherapeutic agents. Understanding how structural characteristics affect solution-phase properties is essential ...