Now showing items 11-20 of 1362
Synthesis of N2‐Substituted Deoxyguanosine Nucleosides from 2‐Fluoro‐6‐O‐(Trimethylsilylethyl)‐2′‐Deoxyinosine
(Wiley Periodicals, Inc.Aldrich Chemical Co., 2000-02)
Syntheses of N2‐substituted nucleosides have been studied for many years, primarily with ribonucleosides. However, the primary route to these compounds requires acidic conditions that are too vigorous for the acid‐labile ...
The severity of osteogenesis imperfecta: A comparison to the relative free energy differences of collagen model peptides
(Wiley Subscription Services, Inc., A Wiley Company, 2011-03)
Molecular dynamics simulations were carried out to calculate free energy differences between the folded and unfolded states of wild type and mutant collagen model peptides. The calculated stability of the collagen models ...
Computational analysis of unassigned high-quality MS/MS spectra in proteomic data sets
(WILEY-VCH Verlag, 2010-07)
In a typical shotgun proteomics experiment, a significant number of high-quality MS/MS spectra remain “unassigned.” The main focus of this work is to improve our understanding of various sources of unassigned high-quality ...
Effect of Coadsorbed Water on Deep Oxidation Mechanisms: Temperature-Programmed Reactions of Benzene and Hydroxyl on the Pt(111) Surface
(Kluwer Academic Publishers; Plenum Publishing Corporation ; Springer Science+Business Media, 2004-03)
The deep oxidation of benzene by preadsorbed hydroxyl on the Pt(111) surface has been characterized using temperature-programmed reaction spectroscopy. A mechanism for benzene oxidation in the presence of coadsorbed water ...
A Structural Model for the Iron–Nitrosyl Adduct of Gentisate Dioxygenase
(Wiley Periodicals, Inc.Oxford University Press, 2018-12-02)
2-(3-Pyrrolin-1-yl)-1,4-naphthoquinones: Photoactivated Alkylating Agents
(WILEY-VCH Verlag, 2008-09)
The preparation of 2-(3-pyrrolin-1-yl)-1,4-naphthoquinones and a study of their use as photoactivated alkylating agents is reported. The title compounds were easily synthesized by conjugate addition of the corresponding ...
Studies on the Biosynthesis of the Stephacidin and Notoamide Natural Products: A Stereochemical and Genetic Conundrum
(WILEY-VCH Verlag, 2011-04)
The stephacidin and notoamide natural products belong to a group of prenylated indole alkaloids containing a bicyclo[2.2.2]diazaoctane core. Biosynthetically, this bicyclic core is believed to be the product of an ...
Molecular Design Approach Managing Molecular Orbital Superposition for High Efficiency without Color Shift in Thermally Activated Delayed Fluorescent Organic Lightâ Emitting Diodes
(Wiley Periodicals, Inc., 2019-02-01)
Molecular design principles of thermally activated delayed fluorescent (TADF) emitters having a high quantum efficiency and a color tuning capability was investigated by synthesizing three TADF emitters with donors at ...