View Item 

Show simple item record

Large unit red cell cryopreservation with hydroxyethyl starch
dc.contributor.authorAllen, Edward D.en_US
dc.contributor.authorWeatherbee, Leeen_US
dc.contributor.authorSpencer, H. H. (Herbert H.)en_US
dc.contributor.authorLindenauer, S. Martinen_US
dc.contributor.authorPermoad, P. A.en_US
dc.date.accessioned2006-04-07T16:25:45Z
dc.date.available2006-04-07T16:25:45Z
dc.date.issued1976-10en_US
dc.identifier.citationAllen, E. D., Weatherbee, L., Spencer, H. H., Lindenauer, S. M., Permoad, P. A. (1976/10)."Large unit red cell cryopreservation with hydroxyethyl starch." Cryobiology 13(5): 500-506. <http://hdl.handle.net/2027.42/21672>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6WD5-4F1RW9F-BR/2/77131e8a01a09dd8f154c281c8e58b5cen_US
dc.identifier.urihttps://hdl.handle.net/2027.42/21672
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=61834&dopt=citationen_US
dc.description.abstractFull units of red blood cells frozen with 14% hydroxyethyl starch (HES) yield cell recoveries near 97% and saline stabilities greater than 80%. Potassium leaves the cells during the freeze-thaw cycle and increases the extracellular concentration of this ion to near 35 meq/l. Unwashed cells (those with plasma present) and saline washed cells yield similar results. Storage of the thawed red cells at 4 [deg]C for up to 48 hr causes little change in the cells.Examination by electron microscopy of samples from thawed units reveals some red cells with portions of their membrane missing. We believe this represents damage from the freeze-thaw cycle and also that all free supernatant hemoglobin does not arise from completely lysed cells.en_US
dc.format.extent3939193 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titleLarge unit red cell cryopreservation with hydroxyethyl starchen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelPublic Healthen_US
dc.subject.hlbsecondlevelStatistics and Numeric Dataen_US
dc.subject.hlbsecondlevelNatural Resources and Environmenten_US
dc.subject.hlbsecondlevelMathematicsen_US
dc.subject.hlbsecondlevelEcology and Evolutionary Biologyen_US
dc.subject.hlbsecondlevelBiological Chemistryen_US
dc.subject.hlbtoplevelSocial Sciencesen_US
dc.subject.hlbtoplevelScienceen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumMedical Research, Veterans Administration Hospital and University of Michigan Medical Center, Ann Arbor, Michigan 48105, USAen_US
dc.contributor.affiliationumMedical Research, Veterans Administration Hospital and University of Michigan Medical Center, Ann Arbor, Michigan 48105, USAen_US
dc.contributor.affiliationumMedical Research, Veterans Administration Hospital and University of Michigan Medical Center, Ann Arbor, Michigan 48105, USAen_US
dc.contributor.affiliationumMedical Research, Veterans Administration Hospital and University of Michigan Medical Center, Ann Arbor, Michigan 48105, USAen_US
dc.contributor.affiliationumMedical Research, Veterans Administration Hospital and University of Michigan Medical Center, Ann Arbor, Michigan 48105, USAen_US
dc.identifier.pmid61834en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/21672/1/0000060.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/0011-2240(76)90143-7en_US
dc.identifier.sourceCryobiologyen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


Files in this item

Name:
0000060.pdf
Size:
3.756MB
Format:
PDF
View/Open

Show simple item record

Remediation of Harmful Language

The University of Michigan Library aims to describe library materials in a way that respects the people and communities who create, use, and are represented in our collections. Report harmful or offensive language in catalog records, finding aids, or elsewhere in our collections anonymously through our metadata feedback form. More information at Remediation of Harmful Language.

Accessibility

If you are unable to use this file in its current format, please select the Contact Us link and we can modify it to make it more accessible to you.