Immunochemical studies on methyl [alpha]- and methyl [beta]-glucosaminide-azoprotein conjugates
dc.contributor.author | Allen, Peter Z. | en_US |
dc.contributor.author | Buss, David H. | en_US |
dc.contributor.author | Goldstein, Irwin J. | en_US |
dc.date.accessioned | 2006-04-07T16:26:02Z | |
dc.date.available | 2006-04-07T16:26:02Z | |
dc.date.issued | 1976-09 | en_US |
dc.identifier.citation | Allen, Peter Z., Buss, David H., Goldstein, Irwin J. (1976/09)."Immunochemical studies on methyl [alpha]- and methyl [beta]-glucosaminide-azoprotein conjugates." Archives of Biochemistry and Biophysics 176(1): 244-249. <http://hdl.handle.net/2027.42/21681> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6WB5-4DN458K-TS/2/f9a8e96754b34a472978bf77103211a3 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/21681 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=823874&dopt=citation | en_US |
dc.description.abstract | Conjugates consisting of methyl 2(p-azobenzamido)2-deoxy-[alpha]--glucopyranoside and methyl 2(p-azobenzamido)-2-[beta]--glucopyranoside coupled to bovine serum albumin were used as synthetic antigens. Rabbits immunized with artificial antigen provided specific anti-methyl [alpha]-glucosaminide or anti-methyl [beta]-glucosaminide anti-hapten sera. Quantitative hapten inhibition was employed to elucidate the specificity of anti-hapten combining sites and to evaluate some structural and configurational features contributing to the immunochemical interaction with the antibody. It is shown that the configuration at the anomeric carbon atom makes a major contribution to the immunochemical specificity of the anti-hapten antibodies against [alpha]- and [beta]-methyl glycosides. | en_US |
dc.format.extent | 501841 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | Immunochemical studies on methyl [alpha]- and methyl [beta]-glucosaminide-azoprotein conjugates | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Public Health | en_US |
dc.subject.hlbsecondlevel | Chemistry | en_US |
dc.subject.hlbsecondlevel | Chemical Engineering | en_US |
dc.subject.hlbsecondlevel | Biological Chemistry | en_US |
dc.subject.hlbtoplevel | Engineering | en_US |
dc.subject.hlbtoplevel | Science | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Biological Chemistry, The University of Michigan, Ann Arbor, Michigan, USA | en_US |
dc.contributor.affiliationother | Department of Microbiology, University of Rochester Medical Center, Rochester, New York, USA | en_US |
dc.contributor.affiliationother | Department of Microbiology, University of Rochester Medical Center, Rochester, New York, USA | en_US |
dc.identifier.pmid | 823874 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/21681/1/0000071.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0003-9861(76)90162-4 | en_US |
dc.identifier.source | Archives of Biochemistry and Biophysics | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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