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The effect of memory blocking antibiotics and their analogs on acetylcholinesterase
dc.contributor.authorSpringer, Alan D.en_US
dc.contributor.authorSchacht, Jochenen_US
dc.contributor.authorAgranoff, Bernard W.en_US
dc.date.accessioned2006-04-07T16:27:28Z
dc.date.available2006-04-07T16:27:28Z
dc.date.issued1976-07en_US
dc.identifier.citationSpringer, Alan D., Schacht, J., Agranoff, B. W. (1976/07)."The effect of memory blocking antibiotics and their analogs on acetylcholinesterase." Pharmacology Biochemistry and Behavior 5(1): 1-3. <http://hdl.handle.net/2027.42/21729>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6T0N-475J5NX-19K/2/cdebc92b8dc2ae45038d956f51dc4e46en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/21729
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=996038&dopt=citationen_US
dc.description.abstractThe ability of antibiotics to inhibit acetylcholinesterase was measured in homogenates of goldfish brain. Puromycin aminonucleoside was the most potent inhibitor followed by puromycin, cycloheximide and acetoxycycloheximide. Puromycin effectively impaired retention of active-avoidance learning in goldfish when injected either immediately before or after training, while puromycin aminonucleoside did not regardless of injection time. These results suggest that the known amnestic effects of puromycin, cycloheximide and acetoxycycloheximide are not a consequence of interference with acetylcholinesterase.en_US
dc.format.extent220112 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titleThe effect of memory blocking antibiotics and their analogs on acetylcholinesteraseen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelBiological Chemistryen_US
dc.subject.hlbtoplevelScienceen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumNeuroscience Laboratory University of Michigan, Ann Arbor, MI 48109, USAen_US
dc.contributor.affiliationumKresge Hearing Research Institute, University of Michigan, Ann Arbor, MI 48109, USA: Neuroscience Laboratory University of Michigan, Ann Arbor, MI 48109, USAen_US
dc.contributor.affiliationumNeuroscience Laboratory University of Michigan, Ann Arbor, MI 48109, USAen_US
dc.identifier.pmid996038en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/21729/1/0000121.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/0091-3057(76)90278-1en_US
dc.identifier.sourcePharmacology Biochemistry and Behavioren_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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