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Energy-linked reactions in hypothyroid rat liver submitochondrial vesicles
dc.contributor.authorEvans, Timothy C.en_US
dc.contributor.authorHoch, Frederic L.en_US
dc.date.accessioned2006-04-07T16:29:26Z
dc.date.available2006-04-07T16:29:26Z
dc.date.issued1976-04-05en_US
dc.identifier.citationEvans, Timothy C., Hoch, Frederic L. (1976/04/05)."Energy-linked reactions in hypothyroid rat liver submitochondrial vesicles." Biochemical and Biophysical Research Communications 69(3): 635-640. <http://hdl.handle.net/2027.42/21791>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6WBK-4DN95FH-WV/2/0958bb491424bd250ad8605e25853cd7en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/21791
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=1267809&dopt=citationen_US
dc.description.abstractProcesses in submitochondrial vesicles obtained from the liver mitochondria of hypothyroid rats were compared at 25-30[deg] with those from normal rats. Hypothyroidism did not alter the rates of oxidation of succinate or [beta]-hydroxybutyrate, or energy-independent transhydrogenation of pyridine nucleotides. Energy-dependent transhydrogenation supported either by added ATP or by succinate oxidation was doubled in the vesicles of hypothyroid rats, whereas ATP-supported reversed electron-flow was unchanged. Hormone injection corrected the abnormal rate. Since submitochondrial vesicles phosphorylate ADP slowly at 30[deg] in hypothyroidism (5), these data suggest that the thyroid state controls the use rather than the supply of available energy potential.en_US
dc.format.extent367346 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titleEnergy-linked reactions in hypothyroid rat liver submitochondrial vesiclesen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelNatural Resources and Environmenten_US
dc.subject.hlbsecondlevelMolecular, Cellular and Developmental Biologyen_US
dc.subject.hlbsecondlevelEcology and Evolutionary Biologyen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.subject.hlbtoplevelScienceen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartments of Biological Chemistry and Internal Medicine The University of Michigan Medical Center, Ann Arbor, Michigan, USAen_US
dc.contributor.affiliationumDepartments of Biological Chemistry and Internal Medicine The University of Michigan Medical Center, Ann Arbor, Michigan, USAen_US
dc.identifier.pmid1267809en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/21791/1/0000186.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/0006-291X(76)90923-2en_US
dc.identifier.sourceBiochemical and Biophysical Research Communicationsen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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