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Integration of avian sarcoma virus specific DNA in mammalian chromatin
dc.contributor.authorDe La Maza, L. M.en_US
dc.contributor.authorFaras, Anthony J.en_US
dc.contributor.authorVarmus, Harold E.en_US
dc.contributor.authorVogt, P. K.en_US
dc.contributor.authorYunis, J. J.en_US
dc.date.accessioned2006-04-07T16:36:43Z
dc.date.available2006-04-07T16:36:43Z
dc.date.issued1975-07en_US
dc.identifier.citationDe La Maza, L. M., Faras, A., Varmus, H., Vogt, P. K., Yunis, J. J. (1975/07)."Integration of avian sarcoma virus specific DNA in mammalian chromatin." Experimental Cell Research 93(2): 484-487. <http://hdl.handle.net/2027.42/22031>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6WFC-4DVNKPC-CK/2/79bc9c625b3289f0b4951216c83dace8en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/22031
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=169136&dopt=citationen_US
dc.description.abstractConstitutive heterochromatin and euchromatin fractions from normal and avian sarcoma virus transformed cells of Mus musculur and Microtus agrestis were isolated in order to characterize the site of integration of the viral specific DNA sequences. The transformed mouse (BALB/c 3T3-B77) and M. agrestis (UMMA-RSV-21) cell lines, as well as a revertant clone of the M. agrestis (UMMA-RSV-R-4) were found to have integrated 1-2 viral copies per diploid genome. The number of viral copies was studied by the technique of DNA-DNA hybridization in solution, and in all cases the viral sequences were located in the euchromatin fraction.en_US
dc.format.extent342246 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titleIntegration of avian sarcoma virus specific DNA in mammalian chromatinen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelMolecular, Cellular and Developmental Biologyen_US
dc.subject.hlbtoplevelScienceen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumUniversity of Michigan, Ann Arbor, MI, USAen_US
dc.contributor.affiliationotherMedical Genetics Division, Department of Laboratory Medicine and Pathology, Mayo Memorial Building, University of Minnesota, Minneapolis, MN 55455, USAen_US
dc.contributor.affiliationotherUniversity of California, San Francisco, CA 94370, USAen_US
dc.contributor.affiliationotherUniversity of Southern California, Los Angeles, CA 94024, USAen_US
dc.contributor.affiliationotherUniversity of Minnesota, Minneapolis, MN 55455, USAen_US
dc.identifier.pmid169136en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/22031/1/0000449.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/0014-4827(75)90477-2en_US
dc.identifier.sourceExperimental Cell Researchen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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