Effects of previous curare-immobilization on Pavlovian conditioned heart decelerations in the curarized rat
dc.contributor.author | Wilson, J. Roger | en_US |
dc.contributor.author | DiCara, Leo V. | en_US |
dc.date.accessioned | 2006-04-07T16:39:25Z | |
dc.date.available | 2006-04-07T16:39:25Z | |
dc.date.issued | 1975-03 | en_US |
dc.identifier.citation | Wilson, J. Roger, Dicara, Leo V. (1975/03)."Effects of previous curare-immobilization on Pavlovian conditioned heart decelerations in the curarized rat." Physiology & Behavior 14(3): 259-264. <http://hdl.handle.net/2027.42/22116> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6T0P-484M9K5-2D/2/03ac2820609ad4a30b6feaadae6f54ec | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/22116 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=124442&dopt=citation | en_US |
dc.description.abstract | Recent evidence indicates that mechanisms other than the vagal-blocking properties of d-tubocurarine chloride (dTC) or inadequate respiration may account for the reports of invariant heart rate (HR) in curarized rats. Two experiments were conducted to determine if repeated dTC-paralysis facilitate acquisition of a Pavlovian HR conditioning in the dTC-paralyzed rat. In Experiment 1, Pavlovian HR conditioning was examined in curarized rats which had (1) experience with dTC-induced immobilization before conditioning, or (2) no experience with dTC-induced immobilization. The results showed that pronounced conditioned HR decelerations were observed only for the curare-experienced animals. Experiment 2 was conducted to determine if repeated curarization influenced tolerance to dTC-induced neuromuscular paralysis. No group differences in basal electromyographic (EMG) activity or time to recover from paralysis were found between the Non-Curare Adapted (NCA), and the Curare Adapted (CA) groups. The implications of the results are discussed in terms of the role of immobilization-induced stress on acquiring stimulus control over autonomic responses. | en_US |
dc.format.extent | 606929 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | Effects of previous curare-immobilization on Pavlovian conditioned heart decelerations in the curarized rat | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Public Health | en_US |
dc.subject.hlbsecondlevel | Psychology | en_US |
dc.subject.hlbsecondlevel | Neurosciences | en_US |
dc.subject.hlbsecondlevel | Molecular, Cellular and Developmental Biology | en_US |
dc.subject.hlbtoplevel | Social Sciences | en_US |
dc.subject.hlbtoplevel | Science | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Psychiatry, Mental Health Research Institute, University of Michigan Medical Center, The University of Michigan, Ann Arbor, Michigan 48104, USA | en_US |
dc.contributor.affiliationum | Department of Psychiatry, Mental Health Research Institute, University of Michigan Medical Center, The University of Michigan, Ann Arbor, Michigan 48104, USA | en_US |
dc.identifier.pmid | 124442 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/22116/1/0000543.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0031-9384(75)90031-1 | en_US |
dc.identifier.source | Physiology & Behavior | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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