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Dual control of lysogeny by bacteriophage P22: An antirepressor locus and its controlling elements

dc.contributor.authorLevine, Myronen_US
dc.contributor.authorTruesdell, Susanen_US
dc.contributor.authorRamakrishnan, T.en_US
dc.contributor.authorBronson, Morley J.en_US
dc.date.accessioned2006-04-07T16:39:38Z
dc.date.available2006-04-07T16:39:38Z
dc.date.issued1975-02-05en_US
dc.identifier.citationLevine, Myron, Truesdell, Susan, Ramakrishnan, T., Bronson, Morley J. (1975/02/05)."Dual control of lysogeny by bacteriophage P22: An antirepressor locus and its controlling elements." Journal of Molecular Biology 91(4): 421-438. <http://hdl.handle.net/2027.42/22123>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6WK7-4DPBWW0-70/2/88912b7812d4222bb9e6217601d5149een_US
dc.identifier.urihttps://hdl.handle.net/2027.42/22123
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=1097696&dopt=citationen_US
dc.description.abstractTwo distantly linked clusters of genes on the Salmonella typhimurium phage P22 chromosome are involved in the control of lysogeny and superinfection immunity. One cluster consists of genes c1, c2, and c3, which are primarily responsible for the establishment and maintenance of lysogeny. It has been proposed that the second cluster consists of three loci which are responsible for the synthesis and control of an antirepressor substance which overcomes the repression mediated by the c2 gene product. This paper reports the isolation of mutants in a locus designated "ant" having characteristics expected of antirepressor mutants. Evidence is presented that the other loci in this second immunity region, mnt and virA, control the expression of the ant gene as represser and promoter/operator, respectively. The interactions of these three loci with each other and with the other immunity region are discussed.en_US
dc.format.extent1490637 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titleDual control of lysogeny by bacteriophage P22: An antirepressor locus and its controlling elementsen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelNatural Resources and Environmenten_US
dc.subject.hlbsecondlevelMolecular, Cellular and Developmental Biologyen_US
dc.subject.hlbsecondlevelEcology and Evolutionary Biologyen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.subject.hlbtoplevelScienceen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Human Genetics University of Michigan, Ann Arbor, Mich. 48104, U.S.A.en_US
dc.contributor.affiliationumDepartment of Human Genetics University of Michigan, Ann Arbor, Mich. 48104, U.S.A.en_US
dc.contributor.affiliationumDepartment of Human Genetics University of Michigan, Ann Arbor, Mich. 48104, U.S.A.en_US
dc.contributor.affiliationumDepartment of Human Genetics University of Michigan, Ann Arbor, Mich. 48104, U.S.A.en_US
dc.identifier.pmid1097696en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/22123/1/0000550.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/0022-2836(75)90270-3en_US
dc.identifier.sourceJournal of Molecular Biologyen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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