The kinetics and mechanisms of reactions of human tooth enamel in buffered solutions of high fluoride concentrations
dc.contributor.author | Higuchi, William I. | en_US |
dc.contributor.author | Valvani, S. C. | en_US |
dc.contributor.author | Hefferren, John J. | en_US |
dc.date.accessioned | 2006-04-07T16:44:49Z | |
dc.date.available | 2006-04-07T16:44:49Z | |
dc.date.issued | 1974-09 | en_US |
dc.identifier.citation | Higuchi, W. I., Valvani, S. C., Hefferren, J. J. (1974/09)."The kinetics and mechanisms of reactions of human tooth enamel in buffered solutions of high fluoride concentrations." Archives of Oral Biology 19(9): 737-746. <http://hdl.handle.net/2027.42/22291> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6T4J-4BWHMSV-1XX/2/336db570e142db54a23707f6a1fe1b0d | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/22291 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=4533725&dopt=citation | en_US |
dc.description.abstract | The experimental results were quantitatively compared with the theory based on a physical model representing the reaction and with the experiments involving synthetic hydroxyapatite discs. The experimental initial rates self-consistently compared well with the theoretical predictions. An analysis of the experimental initial rate data yielded a reaction constant, [kappa], for the reaction representing apatite dissolution and calcium fluoride precipitation. It is proposed that the value for [kappa] is a result of both supersaturation with respect to calcium fluoride and undersaturation with respect to apatite at the apatite-calcium fluoride reaction sites. This finding is also consistent with the analysis of the experiments with synthetic apatite discs.Important similarities and significant differences were found between the experiments with the enamel sections and with synthetic apatite discs. The experiments with the synthetic apatite discs were reported to proceed "normally" as predicted by the physical model over the entire course of the reaction. In contrast to these findings, while the initial rates of the enamel-fluoride reaction were found to proceed relatively rapidly and according to the theoretical predictions, the rates at later times were drastically reduced. This "choking off" was observed to be most severe in the experiments at low pH and high fluoride concentrations, and little or no "choking oft" was observed at low fluoride concentrations and high pH. | en_US |
dc.format.extent | 948128 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | The kinetics and mechanisms of reactions of human tooth enamel in buffered solutions of high fluoride concentrations | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Dentistry | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | College of Pharmacy, University of Michigan, Ann Arbor, Mich. 48104; American Dental Association, Chicago, Ill. 60611, U.S.A. | en_US |
dc.contributor.affiliationum | College of Pharmacy, University of Michigan, Ann Arbor, Mich. 48104; American Dental Association, Chicago, Ill. 60611, U.S.A. | en_US |
dc.contributor.affiliationum | College of Pharmacy, University of Michigan, Ann Arbor, Mich. 48104; American Dental Association, Chicago, Ill. 60611, U.S.A. | en_US |
dc.identifier.pmid | 4533725 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/22291/1/0000731.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0003-9969(74)90160-5 | en_US |
dc.identifier.source | Archives of Oral Biology | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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