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The effect of temperature on cerebrovascular resistance and cerebral metabolism in the primate

dc.contributor.authorGiannotta, Steven L.en_US
dc.contributor.authorRaisis, James E.en_US
dc.contributor.authorMcGillicuddy, John E.en_US
dc.contributor.authorKindt, Glenn W.en_US
dc.date.accessioned2006-04-07T16:59:52Z
dc.date.available2006-04-07T16:59:52Z
dc.date.issued1978-08en_US
dc.identifier.citationGiannotta, Steven L., Raisis, James E., McGillicuddy, John E., Kindt, Glenn W. (1978/08)."The effect of temperature on cerebrovascular resistance and cerebral metabolism in the primate." Journal of Surgical Research 25(2): 105-110. <http://hdl.handle.net/2027.42/22554>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6WM6-4BNF5PG-36F/2/ceb3b37c2825079845b33a46d84795e8en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/22554
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=98668&dopt=citationen_US
dc.description.abstractUsing a primate single carotid perfusion model we studied CVR and A-VO2 differences through a wide range of cerebral temperatures. By keeping cerebral blood flow constant and systemic temperature normal, the influence of systemic blood pressure and low cerebral blood flow was avoided. Our data suggest a direct relationship between temperature and CVR as well as oxygen extraction. A-VO2 differences became less marked below 15[deg]C and are probably negligible when considering hypothermia for most clinical uses.en_US
dc.format.extent457252 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titleThe effect of temperature on cerebrovascular resistance and cerebral metabolism in the primateen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelSurgery and Anesthesiologyen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumUniversity of Michigan Medical Center, Ann Arbor, Michigan 48109, USAen_US
dc.contributor.affiliationumUniversity of Michigan Medical Center, Ann Arbor, Michigan 48109, USAen_US
dc.contributor.affiliationumUniversity of Michigan Medical Center, Ann Arbor, Michigan 48109, USAen_US
dc.contributor.affiliationumUniversity of Michigan Medical Center, Ann Arbor, Michigan 48109, USAen_US
dc.identifier.pmid98668en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/22554/1/0000099.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/0022-4804(78)90062-8en_US
dc.identifier.sourceJournal of Surgical Researchen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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