Regeneration following denervation of minced gastrocnemius muscles in mice
dc.contributor.author | Mufti, Shahzad A. | en_US |
dc.date.accessioned | 2006-04-07T17:09:25Z | |
dc.date.available | 2006-04-07T17:09:25Z | |
dc.date.issued | 1977-08 | en_US |
dc.identifier.citation | Mufti, Shahzad A. (1977/08)."Regeneration following denervation of minced gastrocnemius muscles in mice." Journal of the Neurological Sciences 33(1-2): 251-266. <http://hdl.handle.net/2027.42/22862> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6T06-482R9DM-7T/2/4257636438b1b1d7624a872b6c11d39f | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/22862 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=143509&dopt=citation | en_US |
dc.description.abstract | Gastrocnemius muscles in mice were minced and orthotopically implanted. At the same time all nervous supply to this muscle was completely removed. It was observed that initially the pattern of muscle regeneration was similar to what was observed in a normally innervated implant. But by day 6, distinct degeneration of regenerated muscle fibres sets in, which continues unabated so that by about 3 weeks there usually remains only a thin band of connective tissue in place of the implant.Histochemically, there is a gradual loss of SDH, myofibrillar ATPase and cholinesterase activities within the degenerating muscle fibres and a corresponding appearance of these enzymes in the regenerating fibres. In the denervated implants, with the onset of degeneration of the regenerating fibres, the enzymatic activities were also lost. Histochemical fibre typing was not achieved within the regenerating fibres.The regeneration and degeneration pattern of the denervated muscle observed in the present study is compared with the one observed in other animals. | en_US |
dc.format.extent | 1973994 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | Regeneration following denervation of minced gastrocnemius muscles in mice | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Psychiatry | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Zoology, University of the Punjab, New Campus, Lahore, Pakistan.; Department of Anatomy, University of Michigan, Ann Arbor, Mich. 48104, U.S.A. | en_US |
dc.identifier.pmid | 143509 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/22862/1/0000424.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0022-510X(77)90198-8 | en_US |
dc.identifier.source | Journal of the Neurological Sciences | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
Files in this item
Remediation of Harmful Language
The University of Michigan Library aims to describe library materials in a way that respects the people and communities who create, use, and are represented in our collections. Report harmful or offensive language in catalog records, finding aids, or elsewhere in our collections anonymously through our metadata feedback form. More information at Remediation of Harmful Language.
Accessibility
If you are unable to use this file in its current format, please select the Contact Us link and we can modify it to make it more accessible to you.