Inhibition of rat mixed lymphocyte cultures by suppressor macrophages
dc.contributor.author | Oehler, J. Ronald | en_US |
dc.contributor.author | Herberman, Ronald B. | en_US |
dc.contributor.author | Campbell, Jr. , Darrell A. | en_US |
dc.contributor.author | Djeu, Julie Y. | en_US |
dc.date.accessioned | 2006-04-07T17:12:28Z | |
dc.date.available | 2006-04-07T17:12:28Z | |
dc.date.issued | 1977-03-15 | en_US |
dc.identifier.citation | Oehler, J. Ronald, Herberman, Ronald B., Campbell, Jr., Darrell A., Djeu, Julie Y. (1977/03/15)."Inhibition of rat mixed lymphocyte cultures by suppressor macrophages." Cellular Immunology 29(2): 238-250. <http://hdl.handle.net/2027.42/22959> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6WCF-4F8KJSB-6Y/2/4fc0a894a18cfaa6cbae264a8d909ae5 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/22959 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=140766&dopt=citation | en_US |
dc.description.abstract | Normal rat spleens contain suppressor cells which can inhibit proliferative and cytotoxic responses of lymphocytes to alloantigens in vitro. The suppressor cells are adherent, phagocytic, resistant to treatment with ATS and C, radioresistant, resistant to treatment with mitomycin C, apparently absent from the thymus, and found in very high concentrations in peritoneal exudates. These characteristics indicate that the suppressor cell is a macrophages and not a T cell. When suppressor cells were removed from spleen cell suspensions, strong in vitro proliferative and cytotoxic responses to alloantigens could consistently be observed. | en_US |
dc.format.extent | 887224 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | Inhibition of rat mixed lymphocyte cultures by suppressor macrophages | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Public Health | en_US |
dc.subject.hlbsecondlevel | Biological Chemistry | en_US |
dc.subject.hlbtoplevel | Science | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Laboratory of Immunodiagnosis, National Cancer Institute, Bethesda, Maryland 20014, U.S.A.; Department of General Surgery, University of Michigan Hospital, Ann Arbor, Michigan 48104, U.S.A. | en_US |
dc.contributor.affiliationum | Department of General Surgery, University of Michigan Hospital, Ann Arbor, Michigan 48104, U.S.A.; Laboratory of Immunodiagnosis, National Cancer Institute, Bethesda, Maryland 20014, U.S.A. | en_US |
dc.contributor.affiliationother | Laboratory of Immunodiagnosis, National Cancer Institute, Bethesda, Maryland 20014, U.S.A. | en_US |
dc.contributor.affiliationother | Department of Immunology, Litton Bionetics, Inc., 5516 Nicholson Lane, Kensington, Maryland 20795, U.S.A. | en_US |
dc.identifier.pmid | 140766 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/22959/1/0000526.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0008-8749(77)90319-7 | en_US |
dc.identifier.source | Cellular Immunology | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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