The timing of erf-mediated recombination in replication, lysogenization, and the formation of recombinant progeny by Salmonella phage P22
dc.contributor.author | Weaver, Steven | en_US |
dc.contributor.author | Levine, Myron | en_US |
dc.date.accessioned | 2006-04-07T17:14:05Z | |
dc.date.available | 2006-04-07T17:14:05Z | |
dc.date.issued | 1977-01 | en_US |
dc.identifier.citation | Weaver, Steven, Levine, Myron (1977/01)."The timing of erf-mediated recombination in replication, lysogenization, and the formation of recombinant progeny by Salmonella phage P22." Virology 76(1): 19-28. <http://hdl.handle.net/2027.42/23011> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6WXR-4BNVHWH-J4/2/eb80ac271af515053677c81effe659bd | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/23011 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=319593&dopt=citation | en_US |
dc.description.abstract | Following infection, the development of phage P22 by either the lytic or the lysogenic pathways requires recombination, mediated either by the phage erf system or by the bacterial rec system [Botstein, D., and Matz, M. J. (1970) J. Mol. Biol. 54, 417-440]. We have investigated the timing of the essential recombinational processes with temperature-shift experiments using a temperature-sensitive erf mutant. In rec- cells, erf function appears to be required early in the infection to complete some essential step, the timing of which is the same in both the lytic and lysogenic circumstances. Once the step has taken place, subsequent development can occur without further erf function. However, the bulk of recombinant progeny arising in lytic crosses in rec- cells result from nonessential erf action late in the infection, after the time of the required early step. | en_US |
dc.format.extent | 932224 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | The timing of erf-mediated recombination in replication, lysogenization, and the formation of recombinant progeny by Salmonella phage P22 | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Public Health | en_US |
dc.subject.hlbsecondlevel | Biological Chemistry | en_US |
dc.subject.hlbtoplevel | Science | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Human Genetics, The University of Michigan, Ann Arbor, Michigan 48109, USA | en_US |
dc.contributor.affiliationum | Department of Human Genetics, The University of Michigan, Ann Arbor, Michigan 48109, USA | en_US |
dc.identifier.pmid | 319593 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/23011/1/0000580.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0042-6822(77)90277-X | en_US |
dc.identifier.source | Virology | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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