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The course of autoimmune disease in parous NZB/NZW mice

dc.contributor.authorCastor, Rebeccaen_US
dc.contributor.authorWalker, Sara Ellenen_US
dc.date.accessioned2006-04-07T17:14:14Z
dc.date.available2006-04-07T17:14:14Z
dc.date.issued1977-01en_US
dc.identifier.citationCastor, Rebecca, Walker, Sara Ellen (1977/01)."The course of autoimmune disease in parous NZB/NZW mice." Journal of Comparative Pathology 87(1): 35-42. <http://hdl.handle.net/2027.42/23016>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6WHW-4DCW252-KC/2/03eb56dbfcb9cd14f2e7a582172964d3en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/23016
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=300081&dopt=citationen_US
dc.description.abstractIn a study designed to investigate the effects of pregnancy and parturition on spontaneous lupus-like disease in NZB/NZW mice, 24 female mice were allowed to breed repeatedly with male NZB/NZW mice. Control female mice were caged separately without male mice. Seven months after the study began, the extent of autoimmune disease in parous and control animals was determined by assessing anti-DNA antinuclear antibodies, and the severity of renal lesions. Disease activity in both groups of mice was the same, indicating that pregnancy and parturition had no influence on autoantibody levels or severity of renal disease. It was concluded that bearing young had no effect on the course of autoimmune disease in NZB/NZW mice.en_US
dc.format.extent1764152 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titleThe course of autoimmune disease in parous NZB/NZW miceen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelPathologyen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumRackham Arthritis Research Unit, Department of Internal Medicine, The University of Michigan Medical School, Ann Arbor, Michigan 48109, USAen_US
dc.contributor.affiliationumRackham Arthritis Research Unit, Department of Internal Medicine, The University of Michigan Medical School, Ann Arbor, Michigan 48109, USAen_US
dc.identifier.pmid300081en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/23016/1/0000585.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/0021-9975(77)90077-9en_US
dc.identifier.sourceJournal of Comparative Pathologyen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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