The course of autoimmune disease in parous NZB/NZW mice
dc.contributor.author | Castor, Rebecca | en_US |
dc.contributor.author | Walker, Sara Ellen | en_US |
dc.date.accessioned | 2006-04-07T17:14:14Z | |
dc.date.available | 2006-04-07T17:14:14Z | |
dc.date.issued | 1977-01 | en_US |
dc.identifier.citation | Castor, Rebecca, Walker, Sara Ellen (1977/01)."The course of autoimmune disease in parous NZB/NZW mice." Journal of Comparative Pathology 87(1): 35-42. <http://hdl.handle.net/2027.42/23016> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6WHW-4DCW252-KC/2/03eb56dbfcb9cd14f2e7a582172964d3 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/23016 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=300081&dopt=citation | en_US |
dc.description.abstract | In a study designed to investigate the effects of pregnancy and parturition on spontaneous lupus-like disease in NZB/NZW mice, 24 female mice were allowed to breed repeatedly with male NZB/NZW mice. Control female mice were caged separately without male mice. Seven months after the study began, the extent of autoimmune disease in parous and control animals was determined by assessing anti-DNA antinuclear antibodies, and the severity of renal lesions. Disease activity in both groups of mice was the same, indicating that pregnancy and parturition had no influence on autoantibody levels or severity of renal disease. It was concluded that bearing young had no effect on the course of autoimmune disease in NZB/NZW mice. | en_US |
dc.format.extent | 1764152 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | The course of autoimmune disease in parous NZB/NZW mice | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Pathology | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Rackham Arthritis Research Unit, Department of Internal Medicine, The University of Michigan Medical School, Ann Arbor, Michigan 48109, USA | en_US |
dc.contributor.affiliationum | Rackham Arthritis Research Unit, Department of Internal Medicine, The University of Michigan Medical School, Ann Arbor, Michigan 48109, USA | en_US |
dc.identifier.pmid | 300081 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/23016/1/0000585.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0021-9975(77)90077-9 | en_US |
dc.identifier.source | Journal of Comparative Pathology | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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