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DISORDERS OF CHLORIURETIC HORMONE SECRETION
dc.contributor.authorGrekin, Roger J.en_US
dc.contributor.authorPadfield, P. L.en_US
dc.contributor.authorNicholls, M. Garyen_US
dc.date.accessioned2006-04-07T17:34:50Z
dc.date.available2006-04-07T17:34:50Z
dc.date.issued1979-05-26en_US
dc.identifier.citationGrekin, R. J., Padfield, P. L., Nicholls, M. G. (1979/05/26)."DISORDERS OF CHLORIURETIC HORMONE SECRETION." The Lancet 313(8126): 1116-1118. <http://hdl.handle.net/2027.42/23565>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6T1B-49MDKF0-3BS/2/cb23a3a3b17dda5dd4c7961513139b18en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/23565
dc.description.abstractExperimental evidence supports the existence of a circulating substance, natriuretic hormone, which augments electrolyte excretion. Because such a hormone probably acts by inhibiting chloride reabsorption in the thick, ascending limb of the loop of Henle it would more accurately be called chloriuretic hormone. Chloriuretic hormone must have an action which resembles that of loop diuretics such as frusemide and ethacrynic acid. An excess of chloriuretic hormone could explain all the manifestations of Bartter's syndrome, whereas a deficiency could account for Gordon's syndrome. Hyporeninaemic hypoaldosteronism may develop in subjects who are unable to increase chloriuretic hormone concentrations appropriately in response to progressive impairment of renal function.en_US
dc.format.extent396354 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titleDISORDERS OF CHLORIURETIC HORMONE SECRETIONen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelMedicine (General)en_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDivisions of Endocrinology and Metabolism, and Hypertension, Department of Internal Medicine, Veterans Administration Medical Center, and University of Michigan Medical School, Ann Arbor, Michigan 48109, U.S.A.en_US
dc.contributor.affiliationumDivisions of Endocrinology and Metabolism, and Hypertension, Department of Internal Medicine, Veterans Administration Medical Center, and University of Michigan Medical School, Ann Arbor, Michigan 48109, U.S.A.en_US
dc.contributor.affiliationumDivisions of Endocrinology and Metabolism, and Hypertension, Department of Internal Medicine, Veterans Administration Medical Center, and University of Michigan Medical School, Ann Arbor, Michigan 48109, U.S.A.en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/23565/1/0000525.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/S0140-6736(79)91794-Xen_US
dc.identifier.sourceThe Lanceten_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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