Relationship of glucose to prevalence of ECG abnormalities at baseline and to 6-yr mortality in Scottish males aged 45-64 yr

Abstract

A community study of more than 3000 persons screened in the Burgh of Renfrew, Scotland, included 1134 men age 45-64 whose baseline casual glucose level was measured in 1972 and who were followed for 6 yr to determine mortality rate. A positive association was found, in univariate analysis, between baseline glucose level and prevalence of ECG abnormalities as defined both by the London Whitehall Study and the U.S. Pooling Project Study. In multivariate analyses of these cross-sectional data, an association was seen for Whitehall but not Pooling Project abnormalities. No association was found between asymptomatic hyperglycemia and coronary mortality at 6 yr, either in univariate, bivariate or multivariate analyses. The clinically-observed excess in coronary mortality among those with symptomatic diabetes mellitus was not in evidence among those with asymptomatic hyperglycemia in this group of middle-aged men.