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Sex differences and estrous cycle dependent variation in rotational behavior elicited by electrical stimulation of the mesostriatal dopamine system

dc.contributor.authorRobinson, Terry E.en_US
dc.contributor.authorCamp, Dianne M.en_US
dc.contributor.authorJacknow, Dale S.en_US
dc.contributor.authorBecker, Jill B.en_US
dc.date.accessioned2006-04-07T17:46:40Z
dc.date.available2006-04-07T17:46:40Z
dc.date.issued1982-11en_US
dc.identifier.citationRobinson, Terry E., Camp, Dianne M., Jacknow, Dale S., Becker, Jill B. (1982/11)."Sex differences and estrous cycle dependent variation in rotational behavior elicited by electrical stimulation of the mesostriatal dopamine system." Behavioural Brain Research 6(3): 273-287. <http://hdl.handle.net/2027.42/23814>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6SYP-484F2XK-3H/2/67db26551633f7991f0db6115b832093en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/23814
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=6890843&dopt=citationen_US
dc.description.abstractIn this study electrical stimulation-induced rotational behavior was used as a behavioral index of mesostriatal dopamine (DA) activity to investigate gender and hormonal influences on the DA system. In female rats we found estrous cycle related variations in electrical stimulation-induced rotational behavior. A constant electrical stimulus produced significantly more turning on the day of estrus, than it did 24 h later, on diestrus 1. Gonadectomy attenuated contraversive rotational behavior in female, but not male rats. In contrast, ovariectomy had no effect on the ipsiversive rotational behavior produced by stimulation of the reticular formation. This evidence supports the idea that endogenous changes in gonadal hormone levels influence the functional activity of the mesostriatal DA system in a sexually dimorphic manneren_US
dc.format.extent901571 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titleSex differences and estrous cycle dependent variation in rotational behavior elicited by electrical stimulation of the mesostriatal dopamine systemen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelPublic Healthen_US
dc.subject.hlbsecondlevelPsychologyen_US
dc.subject.hlbsecondlevelNeurosciencesen_US
dc.subject.hlbsecondlevelMolecular, Cellular and Developmental Biologyen_US
dc.subject.hlbtoplevelSocial Sciencesen_US
dc.subject.hlbtoplevelScienceen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumPsychology Department and Neuroscience Laboratory, University of Michigan, Ann Arbor, MI 48109, U.S.A.en_US
dc.contributor.affiliationumPsychology Department and Neuroscience Laboratory, University of Michigan, Ann Arbor, MI 48109, U.S.A.en_US
dc.contributor.affiliationumPsychology Department and Neuroscience Laboratory, University of Michigan, Ann Arbor, MI 48109, U.S.A.en_US
dc.contributor.affiliationumPsychology Department and Neuroscience Laboratory, University of Michigan, Ann Arbor, MI 48109, U.S.A.en_US
dc.identifier.pmid6890843en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/23814/1/0000053.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/0166-4328(82)90028-6en_US
dc.identifier.sourceBehavioural Brain Researchen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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