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RNA splicing: Advantages of parallel processing
dc.contributor.authorvon Heijne, Gunnaren_US
dc.contributor.authorSavageau, Michael A.en_US
dc.date.accessioned2006-04-07T17:47:09Z
dc.date.available2006-04-07T17:47:09Z
dc.date.issued1982-10-21en_US
dc.identifier.citationvon Heijne, Gunnar, Savageau, Michael A. (1982/10/21)."RNA splicing: Advantages of parallel processing." Journal of Theoretical Biology 98(4): 563-574. <http://hdl.handle.net/2027.42/23829>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6WMD-4F1J831-BH/2/6e0a08eff02f64e9f5ff0e147de0b05fen_US
dc.identifier.urihttps://hdl.handle.net/2027.42/23829
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=7154689&dopt=citationen_US
dc.description.abstractParallel and sequential modes of RNA processing are systematically compared by an analysis of the relevant kinetic reaction schemes. The parallel mode is shown to be superior in the sense that it allows molecules to be processed with larger numbers of introns, smaller losses of immature intermediates, and shorter processing times. It also is more sensitive to variations in the rate constants for individual splice-reactions, and hence more amenable to evolutionary refinements. Quantitatively, the parallel mode agrees well with published experimental data.en_US
dc.format.extent605053 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titleRNA splicing: Advantages of parallel processingen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelNatural Resources and Environmenten_US
dc.subject.hlbsecondlevelMolecular, Cellular and Developmental Biologyen_US
dc.subject.hlbsecondlevelEcology and Evolutionary Biologyen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.subject.hlbtoplevelScienceen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Microbiology and Immunology, The University of Michigan Medical School, Ann Arbor, Michigan 48109, U.S.A.en_US
dc.contributor.affiliationotherResearch Group for Theoretical Biophysics, Department of Theoretical Physics, Royal Institute of Technology, S-100 44, Stockholm, Swedenen_US
dc.identifier.pmid7154689en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/23829/1/0000068.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/0022-5193(82)90138-2en_US
dc.identifier.sourceJournal of Theoretical Biologyen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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