Dynorphin (1-17): Lack of analgesia but evidence for non-opiate electrophysiological and motor effects
dc.contributor.author | Walker, J. Michael | en_US |
dc.contributor.author | Moises, Hylan C. | en_US |
dc.contributor.author | Coy, David H. | en_US |
dc.contributor.author | Young, Elizabeth A. | en_US |
dc.contributor.author | Watson, Stanley J. | en_US |
dc.contributor.author | Akil, Huda | en_US |
dc.date.accessioned | 2006-04-07T17:47:20Z | |
dc.date.available | 2006-04-07T17:47:20Z | |
dc.date.issued | 2006-04-07T17:47:20Z | |
dc.identifier.citation | Walker, J. Michael, Moises, Hylan C., Coy, David H., Young, Elizabeth A., Watson, Stanley J., Akil, Huda ()."Dynorphin (1-17): Lack of analgesia but evidence for non-opiate electrophysiological and motor effects." Life Sciences 31(16-17): 1821-1824. <http://hdl.handle.net/2027.42/23835> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6T99-478B4R6-246/2/5e1d9619f390e0b1e02c7022596673a3 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/23835 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=6130448&dopt=citation | en_US |
dc.description.abstract | Dynorphin and an opiate-inactive fragment des-Tyr-dynorphin produced similar effects on EEG, motor function and hippocampal unit firing. Naloxone had no effect on the actions of dynorphin in these systems and dynorphin failed to produce analgesia upon central administration. These results suggest that dynorphin has a pharmacological character that differs significantly from the classic narcotics. | en_US |
dc.format.extent | 248748 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | Dynorphin (1-17): Lack of analgesia but evidence for non-opiate electrophysiological and motor effects | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Natural Resources and Environment | en_US |
dc.subject.hlbsecondlevel | Molecular, Cellular and Developmental Biology | en_US |
dc.subject.hlbsecondlevel | Ecology and Evolutionary Biology | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.subject.hlbtoplevel | Science | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Physiology University of Michigan, Ann Arbor, Michigan 48109, USA; Mental Health Research Institute, Ann Arbor, Michigan 48109, USA. | en_US |
dc.contributor.affiliationum | Department of Physiology University of Michigan, Ann Arbor, Michigan 48109, USA; Mental Health Research Institute, Ann Arbor, Michigan 48109, USA. | en_US |
dc.contributor.affiliationum | Department of Physiology University of Michigan, Ann Arbor, Michigan 48109, USA; Mental Health Research Institute, Ann Arbor, Michigan 48109, USA. | en_US |
dc.contributor.affiliationum | Department of Physiology University of Michigan, Ann Arbor, Michigan 48109, USA; Mental Health Research Institute, Ann Arbor, Michigan 48109, USA. | en_US |
dc.contributor.affiliationum | Department of Physiology University of Michigan, Ann Arbor, Michigan 48109, USA; Mental Health Research Institute, Ann Arbor, Michigan 48109, USA. | en_US |
dc.contributor.affiliationum | Department of Physiology University of Michigan, Ann Arbor, Michigan 48109, USA; Mental Health Research Institute, Ann Arbor, Michigan 48109, USA. | en_US |
dc.identifier.pmid | 6130448 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/23835/1/0000074.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0024-3205(82)90219-3 | en_US |
dc.identifier.source | Life Sciences | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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