Peptide F (pro-enkephalin fragment) : Radioimmunoassay, and stress-induced changes in adrenal
dc.contributor.author | Alessi, Norman E. | en_US |
dc.contributor.author | Taylor, L. | en_US |
dc.contributor.author | Akil, Huda | en_US |
dc.date.accessioned | 2006-04-07T17:47:26Z | |
dc.date.available | 2006-04-07T17:47:26Z | |
dc.date.issued | 2006-04-07T17:47:26Z | |
dc.identifier.citation | Alessi, N., Taylor, L., Akil, H. ()."Peptide F (pro-enkephalin fragment) : Radioimmunoassay, and stress-induced changes in adrenal." Life Sciences 31(16-17): 1875-1878. <http://hdl.handle.net/2027.42/23838> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6T99-478B4R6-24N/2/4c8fadd378e71cf131620ced638479b7 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/23838 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=7154840&dopt=citation | en_US |
dc.description.abstract | Utilizing a nine amino-acid (Asp-Glu-Leu-Tyr-Pro-Leu-Glu-Val-Glu) non-enkephalin containing fragment of Peptide F from the pro-enkephalin molecule, a radioimmunoassay was developed. Extraction of bovine, rat, and guinea pig adrenomedullary preparations demonstrated this fragment to be present and apparently partially conserved across species. In rats, acute inescapable foot-shock stress led to a significant decrease of the immunoreactive material in the adrenal medulla. Chronic daily stress for two weeks resulted in an inability of the adrenals to alter F levels upon subsequent stress. The existence of F-like immunoreactivity and its alteration by environmental manipulation, suggest that it may play a unique physiological role. | en_US |
dc.format.extent | 216084 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | Peptide F (pro-enkephalin fragment) : Radioimmunoassay, and stress-induced changes in adrenal | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Natural Resources and Environment | en_US |
dc.subject.hlbsecondlevel | Molecular, Cellular and Developmental Biology | en_US |
dc.subject.hlbsecondlevel | Ecology and Evolutionary Biology | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.subject.hlbtoplevel | Science | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Mental Health Research Institute University of Michigan, Ann Arbor, Michigan 48109, USA | en_US |
dc.contributor.affiliationum | Mental Health Research Institute University of Michigan, Ann Arbor, Michigan 48109, USA | en_US |
dc.contributor.affiliationother | Lafayette Clinic, Detroit, Michigan, USA | en_US |
dc.identifier.pmid | 7154840 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/23838/1/0000077.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0024-3205(82)90232-6 | en_US |
dc.identifier.source | Life Sciences | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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