Visualization of opiate receptors and opioid peptides in sequential brain sections
dc.contributor.author | Lewis, Michael E. | en_US |
dc.contributor.author | Khachaturian, Henry | en_US |
dc.contributor.author | Watson, Stanley J. | en_US |
dc.date.accessioned | 2006-04-07T17:49:01Z | |
dc.date.available | 2006-04-07T17:49:01Z | |
dc.date.issued | 1982-09 | en_US |
dc.identifier.citation | Lewis, Michael E., Khachaturian, Henry, Watson, Stanley J. (1982/09)."Visualization of opiate receptors and opioid peptides in sequential brain sections." Life Sciences 31(12-13): 1347-1350. <http://hdl.handle.net/2027.42/23888> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6T99-47CMW11-30/2/2e5359e99b594d9aab717b5eee758192 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/23888 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=6292628&dopt=citation | en_US |
dc.description.abstract | Autoradiographic and immunocytochemical studies were carried out on adjacent sections from formaldehyde-perfused rat brains in order to directly correlate the distribution of opiate receptors and opioid peptides. Perfusion fixation of the brains resulted in a partial loss of specific [3H]naloxone binding with essentially no change in the pharmacological properties of the remaining sites. When the distribution of sites was compared to that of enkaphalin immunoreactivity in adjacent sections, striking correlations were observed in a number of areas throughout the neuraxis. Adjacent section autoradiography-immunocytochemistry should provide a useful tool for relating the anatomical distribution of opiate receptor subtypes to different opioid peptide neuronal systems. | en_US |
dc.format.extent | 392827 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | Visualization of opiate receptors and opioid peptides in sequential brain sections | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Natural Resources and Environment | en_US |
dc.subject.hlbsecondlevel | Molecular, Cellular and Developmental Biology | en_US |
dc.subject.hlbsecondlevel | Ecology and Evolutionary Biology | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.subject.hlbtoplevel | Science | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Mental Health Research Institute University of Michigan, Ann Arbor, Michigan 48109, USA | en_US |
dc.contributor.affiliationum | Mental Health Research Institute University of Michigan, Ann Arbor, Michigan 48109, USA | en_US |
dc.contributor.affiliationum | Mental Health Research Institute University of Michigan, Ann Arbor, Michigan 48109, USA | en_US |
dc.identifier.pmid | 6292628 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/23888/1/0000127.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0024-3205(82)90378-2 | en_US |
dc.identifier.source | Life Sciences | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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