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Discriminative stimulus effects of monohydroxylated phencyclidine metabolites in rhesus monkeys

dc.contributor.authorSolomon, Robert E.en_US
dc.contributor.authorHerling, Seymoreen_US
dc.contributor.authorWoods, James H.en_US
dc.date.accessioned2006-04-07T17:49:11Z
dc.date.available2006-04-07T17:49:11Z
dc.date.issued1982-08-27en_US
dc.identifier.citationSolomon, Robert E., Herling, Seymore, Woods, James H. (1982/08/27)."Discriminative stimulus effects of monohydroxylated phencyclidine metabolites in rhesus monkeys." European Journal of Pharmacology 82(3-4): 233-237. <http://hdl.handle.net/2027.42/23893>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6T1J-4746KJ6-1NT/2/44d4c5d1738a6cf48e2a0db873aa19d9en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/23893
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=7128690&dopt=citationen_US
dc.description.abstractRhesus monkeys were trained to discriminate saline from an injection of ketamine. In tests of stimulus generalization, phencyclidine (PCP) produced dose-related ketamine-appropriate responding in each monkey. Two monohydroxylated PCP metabolites also produced ketamine-like discriminative effects, although only at considerably higher doses than did PCP. A third monohydroxylated PCP metabolite produced only sham-appropriate responding. The results suggest that these PCP metabolites contribute little to the behavioral actions of PCP in the monkey.en_US
dc.format.extent369979 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titleDiscriminative stimulus effects of monohydroxylated phencyclidine metabolites in rhesus monkeysen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelPharmacy and Pharmacologyen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartments of Pharmacology and Psychology, University of Michigan, Ann Arbor, Michigan 48109, U.S.A.en_US
dc.contributor.affiliationumDepartments of Pharmacology and Psychology, University of Michigan, Ann Arbor, Michigan 48109, U.S.A.en_US
dc.contributor.affiliationumDepartments of Pharmacology and Psychology, University of Michigan, Ann Arbor, Michigan 48109, U.S.A.en_US
dc.identifier.pmid7128690en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/23893/1/0000132.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/0014-2999(82)90520-9en_US
dc.identifier.sourceEuropean Journal of Pharmacologyen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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